dbPTM

PPIB_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PPIB_SCHPO
UniProt AC	O94273
Protein Name	Peptidyl-prolyl cis-trans isomerase B
Gene Name	cyp4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	201
Subcellular Localization	Endoplasmic reticulum lumen .
Protein Description	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)..
Protein Sequence	MKLFYFSLLFTLFFGLISANRGPKVTDTVYFDLQQGDEFLGRVTIGLFGKTVPKTAENFRALATGEKGFGYEGSIFHRVIPNFMIQGGDITKGDGTGGKSIYGSRFPDENFKLSHQRPGLLSMANAGPDSNGSQFFITTVKTPWLDGHHVVFGEVLSGYDIVKKISKAETDNRDKPLEDVKIIKSGQLSQENVEDDGTDEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
131	N-linked_Glycosylation	ANAGPDSNGSQFFIT CCCCCCCCCCCEEEE	62.61	-
198	Phosphorylation	ENVEDDGTDEL---- CCCCCCCCCCC----	33.04	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PPIB_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PPIB_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PPIB_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCR4_SCHPO	ccr4	genetic	18818364
ALG8_SCHPO	alg8	genetic	22681890
PLR2_SCHPO	SPCC1281.04	genetic	22681890
YEG5_SCHPO	mga2	genetic	22681890
MYO51_SCHPO	myo51	genetic	22681890
NDK_SCHPO	ndk1	genetic	22681890
ALG6_SCHPO	alg6	genetic	22681890
ARP42_SCHPO	arp42	genetic	22681890
MSC1_SCHPO	msc1	genetic	22681890
YJD1_SCHPO	SPCC594.01	genetic	22681890
VPS3_SCHPO	vps3	genetic	22681890
ATP11_SCHPO	atp11	genetic	22681890
PPK16_SCHPO	ppk16	genetic	22681890
TOM70_SCHPO	tom70	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
ASE1_SCHPO	ase1	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PPIB_SCHPO

Related Literatures of Post-Translational Modification