dbPTM

YNSK_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YNSK_SCHPO
UniProt AC	O60150
Protein Name	Uncharacterized protein C18H10.20c
Gene Name	SPBC18H10.20c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	361
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description
Protein Sequence	MPLKLALPRSTTPKDPARCTLDIRMESPPLVFLGSPETSSGALASGILKLTILHQPFIKVHTLKLQLIKRITVLHPAISHCSACAGSKEVLQTWDLAANTTYRPGTQHWPFSWLFPGSLPASVSNRYIKLEYYLEATLCYGTPEGGISPSKPEVLKFPLQLKRAAIPSPDTIHKRIFPPTNLVANITLPSTLHPHGAALMEVTMTGFAQNDGNDWKINRVTWRLEEHMQFSCQPCERHRDLVKPRPIEEKRILSTQDLQSGWKFIDNQMFLSTQINTSSLREPSCDVEIPAPFSLKVSHHLIFETIVNRKKNVAGNNMGNARILRVSVVQPLTTPAGLGISWDEECPPVFESVGPAPPAYT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
11	Phosphorylation	KLALPRSTTPKDPAR EEECCCCCCCCCCCC	48.69	24763107
12	Phosphorylation	LALPRSTTPKDPARC EECCCCCCCCCCCCC	29.59	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YNSK_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YNSK_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YNSK_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TSC2_SCHPO	tsc2	genetic	23813957
TSC1_SCHPO	tsc1	genetic	23813957
PUB1_SCHPO	pub1	physical	23813957
PUB1_SCHPO	pub1	genetic	23813957
AAT1_SCHPO	aat1	physical	23813957
PUB1_SCHPO	pub1	physical	24876389
PUB1_SCHPO	pub1	genetic	24876389
MCS4_SCHPO	mcs4	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YNSK_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-12, AND MASSSPECTROMETRY.	18257517 [Abstract]