AAT1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AAT1_SCHPO
• UniProt AC: Q9P5N2
• Protein Name: Amino acid transporter 1
• Gene Name: aat1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 579
• Subcellular Localization: Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. When the cells were shifted to a nitrogen-free medium, aat1 was transported from the Golgi apparatus to the plasma membrane within 30 minutes.
• Protein Description: Probable amino acid transporter that may play a role in function in microtubule organization since it causes microtubule defects when overexpressed..
• Protein Sequence: MSAKDYDFDIESVLPEEKAPQVSEAKKDYISQESTVLSGQVDFVEPEHKGFFQNLIDGFKPAREADGNGGPALKRGLSTRHMQLMSIGGAIGSGLYVGSGSALADGGPASVIINYILIGIMMFFVIYALGEMAVAYPVAGSFNTYATRFIDPAWGFAVSWNYFFNYFVTFPFELTTCAITFTFWTDVNCAVWISIFLVVVIGINLFGVRVFGEVEFVLALIKVVATVGFIILAIIINCGGVPTDHRGYIGGSIIKQKPFRHGFKGFCSVYTTAAFSFSGTEIVGLAAAEVGDPRKTLPGAVKQVFWRVAIFYIVSLILIGLLISPDDPKLMGNGSASVSPFVLAIQEANIKGLPSVFNAVIIISVISVTNSSTYTAGRTLHGMANLKQAPAFFKYTDRLGRPLIAMIVVLSFGFFAYINEANNNGNDISDTVFDWLLAISGLSNFFTWGSICLSHIMFRLAFKKQGHSLKELGFVSPMGIWGSVIGLGFNILCLMAEFYVSLFPIGGSPNANDFFQGYLAACITLVFFIGYKIYDRSHIPSLDKLDITTGLKTYEYEETKDSSDTGRFRFFKKIINTVC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSAKDYDFD ------CCCCCCCCC	43.98	29996109
12	Phosphorylation	DYDFDIESVLPEEKA CCCCCHHHCCCCCCC	29.32	24763107
29	Phosphorylation	VSEAKKDYISQESTV CCHHHHHHCCHHHHH	16.02	29996109
31	Phosphorylation	EAKKDYISQESTVLS HHHHHHCCHHHHHHC	22.97	21712547
34	Phosphorylation	KDYISQESTVLSGQV HHHCCHHHHHHCCCC	19.04	21712547
35	Phosphorylation	DYISQESTVLSGQVD HHCCHHHHHHCCCCC	25.39	21712547
38	Phosphorylation	SQESTVLSGQVDFVE CHHHHHHCCCCCCCC	23.89	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AAT1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AAT1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AAT1_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of AAT1_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.