PPK23_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPK23_SCHPO
• UniProt AC: O60145
• Protein Name: Serine/threonine-protein kinase ppk23
• Gene Name: ppk23
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 398
• Subcellular Localization: Nucleus .
• Protein Sequence: MAGSKWETEETNQFAIENQKLEEEWRKKRRLEKKRKRKILEEEEKAEERNIDACRLYLMGNTPELKSCNSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRPKDPKFFPTFPSKAKGESKEKNVFQSFRSASPKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
362	Phosphorylation	EHPYFYESPRPKDPK CCCCCCCCCCCCCCC	18.15	28889911
390	Phosphorylation	KEKNVFQSFRSASPK HHHHHHHHHHHCCCC	15.91	21712547
393	Phosphorylation	NVFQSFRSASPKK-- HHHHHHHHCCCCC--	30.96	21712547
395	Phosphorylation	FQSFRSASPKK---- HHHHHHCCCCC----	38.20	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPK23_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPK23_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPK23_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HIR1_SCHPO	hip1	genetic	18818364
MAD1_SCHPO	mad1	genetic	18818364
FAS1_SCHPO	fas1	physical	23122962
SPT5_SCHPO	spt5	physical	23122962
HSP72_SCHPO	ssa2	physical	23122962
TCPA_SCHPO	cct1	physical	23122962
DED1_SCHPO	sum3	physical	23122962
DBP2_SCHPO	dbp2	physical	23122962
GLYM_SCHPO	shm2	physical	23122962
G3P1_SCHPO	tdh1	physical	23122962
MED10_SCHPO	nut2	physical	23122962
SPT4_SCHPO	spt4	physical	23122962
YFO5_SCHPO	lcp1	physical	23122962
PPK23_SCHPO	cdk11	physical	23122962
MED4_SCHPO	pmc4	physical	23122962
MED27_SCHPO	pmc3	physical	23122962
SSN3_SCHPO	srb10	physical	23122962
SSN2_SCHPO	med13	physical	23122962
MPC2_SCHPO	mpc2	genetic	22681890
HIS4_SCHPO	SPAC3F10.09	genetic	22681890
YCGK_SCHPO	SPCC16C4.20c	genetic	22681890
PROB_SCHPO	SPAC17H9.13c	genetic	22681890
LYS1_SCHPO	lys3	genetic	22681890
YIPL_SCHPO	SPAPJ691.02	genetic	22681890
EFTS_SCHPO	tsf1	genetic	22681890
RS17B_SCHPO	rps1702	genetic	22681890
ARGJ_SCHPO	SPBC1271.14	genetic	22681890
YIW4_SCHPO	SPAC694.04c	genetic	22681890
BST1_SCHPO	bst1	genetic	22681890
NEM1_SCHPO	nem1	genetic	22681890
YGRG_SCHPO	SPBC365.16	genetic	22681890
YE08_SCHPO	SPAC17H9.08	genetic	22681890
OTC_SCHPO	arg3	genetic	22681890
RTF_SCHPO	rtf1	genetic	22681890
DCTD_SCHPO	dcd1	genetic	22681890
ARP42_SCHPO	arp42	genetic	22681890
NAGS_SCHPO	arg6	genetic	22681890
HOSM_SCHPO	lys4	genetic	22681890
LYS4_SCHPO	lys2	genetic	22681890
YL8H_SCHPO	SPAC25B8.17	genetic	22681890
YOI9_SCHPO	SPBC1778.09	genetic	22681890
AATM_SCHPO	SPBC725.01	genetic	22681890
YCF8_SCHPO	SPCC1393.08	genetic	22681890
PYRD_SCHPO	ura3	genetic	22681890
ELP1_SCHPO	elp1	genetic	22681890
ARG56_SCHPO	arg11	genetic	22681890
SPO6_SCHPO	spo6	genetic	22681890
BU107_SCHPO	bun107	genetic	22681890
PPK6_SCHPO	ppk6	genetic	22681890
SPN1_SCHPO	spn1	genetic	22681890
RL19B_SCHPO	rpl1902	genetic	22681890
ASSY_SCHPO	arg12	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.