MOS_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOS_HUMAN
• UniProt AC: P00540
• Protein Name: Proto-oncogene serine/threonine-protein kinase mos
• Gene Name: MOS
• Organism: Homo sapiens (Human).
• Sequence Length: 346
• Protein Sequence: MPSPLALRPYLRSEFSPSVDARPCSSPSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAELG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	PYLRSEFSPSVDARP HHHHCCCCCCCCCCC	16.53	10439036
39	Phosphorylation	AKLLLGATLPRAPRL HHHHHCCCCCCCCCC	35.18	24719451
79	Phosphorylation	GSVYKATYRGVPVAI CCCEEEEECCCCEEE	15.38	22817900
93	Phosphorylation	IKQVNKCTKNRLASR EHHHHHHCCCHHHHC	32.72	29083192
99	Phosphorylation	CTKNRLASRRSFWAE HCCCHHHHCHHHHHH	32.58	29083192
234	Phosphorylation	EDLLCFQTPSYPLGG HHHHCCCCCCCCCCC	8.24	30206219
236	Phosphorylation	LLCFQTPSYPLGGTY HHCCCCCCCCCCCCC	42.65	30206219
237	Phosphorylation	LCFQTPSYPLGGTYT HCCCCCCCCCCCCCC	12.04	30206219
242	Phosphorylation	PSYPLGGTYTHRAPE CCCCCCCCCCCCCCH	24.37	30206219
243	Phosphorylation	SYPLGGTYTHRAPEL CCCCCCCCCCCCCHH	12.11	30206219
244	Phosphorylation	YPLGGTYTHRAPELL CCCCCCCCCCCCHHH	12.53	30206219
263	Phosphorylation	VTPKADIYSFAITLW CCCCHHHHHHHHHHH	9.78	22468782
264	Phosphorylation	TPKADIYSFAITLWQ CCCHHHHHHHHHHHH	14.45	22468782
268	Phosphorylation	DIYSFAITLWQMTTK HHHHHHHHHHHHCCC	20.65	22468782
339	Phosphorylation	RLLLVDLTSLKAELG EEEEEEHHHHHHHHC	27.78	-
340	Phosphorylation	LLLVDLTSLKAELG- EEEEEHHHHHHHHC-	34.86	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOS_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOS_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOS_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYOD1_HUMAN	MYOD1	physical	9001211
TRI27_HUMAN	TRIM27	physical	25416956
TRAF1_HUMAN	TRAF1	physical	25416956
HOME3_HUMAN	HOMER3	physical	25416956
SC24C_HUMAN	SEC24C	physical	25416956
CACO2_HUMAN	CALCOCO2	physical	25416956
TRIM1_HUMAN	MID2	physical	25416956
CCDB1_HUMAN	CCNDBP1	physical	25416956
BORC6_HUMAN	C17orf59	physical	25416956
CC136_HUMAN	CCDC136	physical	25416956
MTMR9_HUMAN	MTMR9	physical	25416956
C102B_HUMAN	CCDC102B	physical	25416956
CCD33_HUMAN	CCDC33	physical	25416956
USBP1_HUMAN	USHBP1	physical	25416956
ATRIP_HUMAN	ATRIP	physical	25416956
LZTS2_HUMAN	LZTS2	physical	25416956
ADIP_HUMAN	SSX2IP	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
DYDC1_HUMAN	DYDC1	physical	25416956
SPERT_HUMAN	SPERT	physical	25416956
STK26_HUMAN	STK26	physical	26186194
STK25_HUMAN	STK25	physical	26186194
BIRC6_HUMAN	BIRC6	physical	26186194
CLU_HUMAN	CLUH	physical	26186194
FKBP5_HUMAN	FKBP5	physical	26186194
2A5E_HUMAN	PPP2R5E	physical	26186194
2A5A_HUMAN	PPP2R5A	physical	26186194
HOME3_HUMAN	HOMER3	physical	21516116
FKBP5_HUMAN	FKBP5	physical	28514442
2A5E_HUMAN	PPP2R5E	physical	28514442
CLU_HUMAN	CLUH	physical	28514442
MINY3_HUMAN	FAM188A	physical	28514442
2A5A_HUMAN	PPP2R5A	physical	28514442
BIRC6_HUMAN	BIRC6	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.