dbPTM

FEX1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FEX1_YEAST
UniProt AC	Q08913
Protein Name	Fluoride export protein 1 {ECO:0000303\|PubMed:24173035}
Gene Name	FEX1 {ECO:0000303\|PubMed:24173035}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	375
Subcellular Localization	Cell membrane Multi-pass membrane protein .
Protein Description	Fluoride channel required for the rapid expulsion of cytoplasmic fluoride..
Protein Sequence	MIFNPVISNHKLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLNAYTWMKDHQVLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTKLPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENAGDVDTQEMEKNILEFKFKTPAPFFKKFFDIVDKLAYALAFPLIILFVVLCAYYENYSRGKWTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTDVPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIAISYCLLVITLGSYAWTRGLTNPIC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
109	N-linked_Glycosylation	EMFEHSTNLTNGNIA HHHHHCCCCCCCCCC	-
117	N-linked_Glycosylation	LTNGNIANHTKLPNR CCCCCCCCCCCCCCH	-
170	Phosphorylation	SSFSKPYTPPSDTVK CCCCCCCCCCCHHCH	27214570
173	Phosphorylation	SKPYTPPSDTVKENA CCCCCCCCHHCHHCC	21551504
175	Phosphorylation	PYTPPSDTVKENAGD CCCCCCHHCHHCCCC	27717283
185	Phosphorylation	ENAGDVDTQEMEKNI HCCCCCCHHHHHHHH	27214570
235	N-linked_Glycosylation	VLCAYYENYSRGKWT HHHHHHHHHCCCCCH	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FEX1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FEX1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FEX1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BUD31_YEAST	BUD31	genetic	20093466
RV167_YEAST	RVS167	genetic	20093466
VAM7_YEAST	VAM7	genetic	20093466
ICE2_YEAST	ICE2	genetic	20093466
PHO91_YEAST	PHO91	genetic	20093466
SOL1_YEAST	SOL1	genetic	20093466
INO4_YEAST	INO4	genetic	20093466
ALG6_YEAST	ALG6	genetic	20093466
OYE3_YEAST	OYE3	genetic	20093466
YP117_YEAST	YPR117W	genetic	20093466
SLU7_YEAST	SLU7	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
HSP77_YEAST	SSC1	genetic	27708008
YJ9I_YEAST	YJR141W	genetic	27708008
BET3_YEAST	BET3	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
EDS1_YEAST	EDS1	genetic	27708008
TPS2_YEAST	TPS2	genetic	27708008
MSC2_YEAST	MSC2	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
BUB1_YEAST	BUB1	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
DAL81_YEAST	DAL81	genetic	27708008
PEX1_YEAST	PEX1	genetic	27708008
FAR3_YEAST	FAR3	genetic	27708008
PHO91_YEAST	PHO91	genetic	27708008
PSH1_YEAST	PSH1	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
MCP1_YEAST	MCP1	genetic	27708008
EF1G1_YEAST	CAM1	genetic	27708008
YPR09_YEAST	YPR109W	genetic	27708008
YP117_YEAST	YPR117W	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FEX1_YEAST

Related Literatures of Post-Translational Modification