ZN414_HUMAN - dbPTM
ZN414_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN414_HUMAN
UniProt AC Q96IQ9
Protein Name Zinc finger protein 414
Gene Name ZNF414
Organism Homo sapiens (Human).
Sequence Length 312
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MEEKPSGPIPDMLATAEPSSSETDKEVLSPAVPAAAPSSSMSEEPGPEQAATPPVWERGGAGGMQQGSSPAPDSCQPGPGPSPGLTSIVSGTSEDLRPPRRRPPPGKQIPCSSPGCCLSFPSVRDLAQHLRTHCPPTQSLEGKLFRCSALSCTETFPSMQELVAHSKLHYKPNRYFKCENCLLRFRTHRSLFKHLHVCAEHAQSPAPPPPPALDREPPAPERPPEVDPASAPGLPFPLLEPFTTPAPAPTGPFLPYLNPAPFGLSPPRLRPFLAAAPGPPASSAAVWKKSQGAGSSPRRPQGGSDAPSGACR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
29 (in isoform 2)Phosphorylation-18.9127251275
29PhosphorylationETDKEVLSPAVPAAA
CCCHHHHCCCCCCCC		18.9122199227
38PhosphorylationAVPAAAPSSSMSEEP
CCCCCCCCCCCCCCC		30.2522199227
39PhosphorylationVPAAAPSSSMSEEPG
CCCCCCCCCCCCCCC		29.0622199227
40PhosphorylationPAAAPSSSMSEEPGP
CCCCCCCCCCCCCCH		30.5722199227
42PhosphorylationAAPSSSMSEEPGPEQ
CCCCCCCCCCCCHHH		40.5322199227
52 (in isoform 2)Phosphorylation-31.0127251275
52PhosphorylationPGPEQAATPPVWERG
CCHHHCCCCCCCCCC		31.0122199227
68PhosphorylationAGGMQQGSSPAPDSC
CCCCCCCCCCCCCCC		28.8928348404
69PhosphorylationGGMQQGSSPAPDSCQ
CCCCCCCCCCCCCCC		31.7226657352
69 (in isoform 2)Phosphorylation-31.7227251275
112PhosphorylationPGKQIPCSSPGCCLS
CCCCCCCCCCCCCCC		33.9225627689
113PhosphorylationGKQIPCSSPGCCLSF
CCCCCCCCCCCCCCC		31.8421712546
139PhosphorylationTHCPPTQSLEGKLFR
HHCCCCCCCCCCEEE		30.76-
148 (in isoform 2)Phosphorylation-28.1724719451
148PhosphorylationEGKLFRCSALSCTET
CCCEEEEECCCCCCC		28.1724719451
153 (in isoform 2)Phosphorylation-34.3824719451
153PhosphorylationRCSALSCTETFPSMQ
EEECCCCCCCCCCHH		34.3824719451
177MethylationYKPNRYFKCENCLLR
CCCCCCCCCCCCHHH		31.53115978227
190 (in isoform 2)Phosphorylation-30.4724719451
190PhosphorylationLRFRTHRSLFKHLHV
HHHHHHHHHHHHHHH		30.4724719451
204PhosphorylationVCAEHAQSPAPPPPP
HHHHHCCCCCCCCCC		24.6620873877
265PhosphorylationNPAPFGLSPPRLRPF
CCCCCCCCCCCCHHH		32.9824719451
270MethylationGLSPPRLRPFLAAAP
CCCCCCCHHHHHCCC		22.62115388085
282PhosphorylationAAPGPPASSAAVWKK
CCCCCCCCHHHHHHH		26.70-
290PhosphorylationSAAVWKKSQGAGSSP
HHHHHHHCCCCCCCC		30.0726074081
290 (in isoform 2)Phosphorylation-30.0724247654
295PhosphorylationKKSQGAGSSPRRPQG
HHCCCCCCCCCCCCC		36.3125159151
295 (in isoform 2)Phosphorylation-36.3128111955
296 (in isoform 2)Phosphorylation-22.8520201521
296PhosphorylationKSQGAGSSPRRPQGG
HCCCCCCCCCCCCCC		22.8525159151
304 (in isoform 2)Phosphorylation-37.1128111955
304PhosphorylationPRRPQGGSDAPSGAC
CCCCCCCCCCCCCCC		37.1126074081
308PhosphorylationQGGSDAPSGACR---
CCCCCCCCCCCC---		40.5226074081
315 (in isoform 2)Methylation--
376 (in isoform 2)Phosphorylation-30108239
380 (in isoform 2)Phosphorylation-30108239
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN414_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN414_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN414_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NPRL3_HUMANNPRL3physical
26186194
KDM4B_HUMANKDM4Bphysical
26186194
EDRF1_HUMANEDRF1physical
26186194
PPR1A_HUMANPPP1R1Aphysical
26186194
DEPD5_HUMANDEPDC5physical
26186194
NPRL2_HUMANNPRL2physical
26186194
DHB8_HUMANHSD17B8physical
26186194
ANGE1_HUMANANGEL1physical
26186194
KDM4B_HUMANKDM4Bphysical
28514442
KDM4A_HUMANKDM4Aphysical
28514442
ZRAN1_HUMANZRANB1physical
28514442
ANR50_HUMANANKRD50physical
28514442
NOC4L_HUMANNOC4Lphysical
28514442
EDRF1_HUMANEDRF1physical
28514442
NOP14_HUMANNOP14physical
28514442
DHB8_HUMANHSD17B8physical
28514442
NPRL2_HUMANNPRL2physical
28514442
2ABD_HUMANPPP2R2Dphysical
28514442
P2R3B_HUMANPPP2R3Bphysical
28514442
CSKP_HUMANCASKphysical
28514442
DCA16_HUMANDCAF16physical
28514442
ANGE1_HUMANANGEL1physical
28514442
DHYS_HUMANDHPSphysical
28514442
AGGF1_HUMANAGGF1physical
28514442
THNS1_HUMANTHNSL1physical
28514442
TOPK_HUMANPBKphysical
28514442
MTMR4_HUMANMTMR4physical
28514442
MK09_HUMANMAPK9physical
28514442
SHCBP_HUMANSHCBP1physical
28514442
ATG3_HUMANATG3physical
28514442
ANR52_HUMANANKRD52physical
28514442
OSBL6_HUMANOSBPL6physical
28514442
SAHH3_HUMANAHCYL2physical
28514442
PNMA2_HUMANPNMA2physical
28514442
KBTB7_HUMANKBTBD7physical
28514442
ANR17_HUMANANKRD17physical
28514442
IPO5_HUMANIPO5physical
28514442
SAHH2_HUMANAHCYL1physical
28514442
GALD1_HUMANPDDC1physical
28514442
ERBIN_HUMANERBB2IPphysical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN414_HUMAN

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Related Literatures of Post-Translational Modification

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