KRT38_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KRT38_HUMAN
• UniProt AC: O76015
• Protein Name: Keratin, type I cuticular Ha8
• Gene Name: KRT38
• Organism: Homo sapiens (Human).
• Sequence Length: 456
• Protein Sequence: MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGSTPLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSCVTAPCAPRPSCGPCTTCGPTCGASTTGSRF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MTSSYSSSSC -----CCCCCCCCCC	26.44	20068231
4	Phosphorylation	----MTSSYSSSSCP ----CCCCCCCCCCC	21.62	20068231
6	Phosphorylation	--MTSSYSSSSCPLG --CCCCCCCCCCCCC	26.20	20068231
7	Phosphorylation	-MTSSYSSSSCPLGC -CCCCCCCCCCCCCC	20.31	20068231
8	Phosphorylation	MTSSYSSSSCPLGCT CCCCCCCCCCCCCCC	29.98	20068231
9	Phosphorylation	TSSYSSSSCPLGCTM CCCCCCCCCCCCCCC	23.00	20068231
15	Phosphorylation	SSCPLGCTMAPGARN CCCCCCCCCCCCCCE	17.99	20068231
59	Phosphorylation	ANRVRVGSTPLGRPS HCCCCCCCCCCCCCC	24.80	-
60	Phosphorylation	NRVRVGSTPLGRPSL CCCCCCCCCCCCCCC	19.32	-
145	Phosphorylation	ERSKCHESTVCPDYQ HHHCCCCCCCCCCHH	11.50	-
157	Phosphorylation	DYQSYFHTIEELQQK CHHHHHHHHHHHHHH	21.86	-
195	Phosphorylation	DFRIKLESERSLRQL CCEEHHHHHHHHHHH	49.06	23312004
218	Phosphorylation	QKLLDDATLAKADLE HHHHCHHHHHHHHHH	33.95	20068231
374	Phosphorylation	SNVEEQLSEIRADLE HCHHHHHHHHHHHHH	30.58	24719451
441	Phosphorylation	RPSCGPCTTCGPTCG CCCCCCCCCCCCCCC	28.40	30576142
446	Phosphorylation	PCTTCGPTCGASTTG CCCCCCCCCCCCCCC	14.62	30576142
450	Phosphorylation	CGPTCGASTTGSRF- CCCCCCCCCCCCCC-	16.28	30576142
451	Phosphorylation	GPTCGASTTGSRF-- CCCCCCCCCCCCC--	34.34	30576142
454	Phosphorylation	CGASTTGSRF----- CCCCCCCCCC-----	28.55	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KRT38_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KRT38_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KRT38_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HGS_HUMAN	HGS	physical	25416956
HDAC4_HUMAN	HDAC4	physical	25416956
HM20B_HUMAN	HMG20B	physical	25416956
GLRX3_HUMAN	GLRX3	physical	25416956
CLM8_HUMAN	CD300A	physical	25416956
KDM1A_HUMAN	KDM1A	physical	25416956
AMOL2_HUMAN	AMOTL2	physical	25416956
F90A1_HUMAN	FAM90A1	physical	25416956
CC146_HUMAN	CCDC146	physical	25416956
SCNM1_HUMAN	SCNM1	physical	25416956
ZFY21_HUMAN	ZFYVE21	physical	25416956
CS057_HUMAN	C19orf57	physical	25416956
TXND5_HUMAN	TXNDC5	physical	25416956
USBP1_HUMAN	USHBP1	physical	25416956
BEX2_HUMAN	BEX2	physical	25416956
ZN587_HUMAN	ZNF587	physical	25416956
K2C71_HUMAN	KRT71	physical	25416956
HAUS1_HUMAN	HAUS1	physical	25416956
CA216_HUMAN	C1orf216	physical	25416956
ZN417_HUMAN	ZNF417	physical	25416956
TXLNB_HUMAN	TXLNB	physical	25416956
TXLNA_HUMAN	TXLNA	physical	25416956
CE57L_HUMAN	CEP57L1	physical	25416956
K2C6C_HUMAN	KRT6C	physical	25416956
K2C79_HUMAN	KRT79	physical	25416956
KLH38_HUMAN	KLHL38	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.