dbPTM

HAUS4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HAUS4_MOUSE
UniProt AC	Q8BFT2
Protein Name	HAUS augmin-like complex subunit 4
Gene Name	Haus4
Organism	Mus musculus (Mouse).
Sequence Length	363
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Localizes to interphase centrosomes and to mitotic spindle microtubules..
Protein Description	Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex..
Protein Sequence	MASGDFCAPGEGVEMLLQVCGKQFPPCALTEEDLIQNPRFSKLLLSLSQHVDESGLSLTLAKEQAQAWSEVRHRKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKKFHETLEQRLLVTELTQLSGPGQETELPPLLGLERTDLLELMPPSQDFVWMKARLQLEVEEQLKRKCFTLLCYHDPSSDTDGDTLKAAKVWTLTEVLVREKQQCLEAKSQQKEQLVLLEKKRTTYSQVLLRCLALLQRLLQEHRLQTKSELDRINAQYLELKCSAMILRLRMEELKVLSDTYSAEKVEMHRLIRDRLEGAIRLQEQDLEKSRLVLHTYEALGEDFESLVREYTQLRLAADNKRWALQELSKAQR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of HAUS4_MOUSE !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HAUS4_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HAUS4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HAUS4_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GNAI1_HUMAN	GNAI1	physical	20360068
PCM1_HUMAN	PCM1	physical	20360068
PLK1_HUMAN	PLK1	physical	20360068
GBB4_HUMAN	GNB4	physical	20360068
HAUS2_HUMAN	HAUS2	physical	20360068
GNAO_HUMAN	GNAO1	physical	20360068
RCN1_HUMAN	RCN1	physical	20360068
HAUS6_HUMAN	HAUS6	physical	20360068
HAUS3_HUMAN	HAUS3	physical	20360068
HAUS8_HUMAN	HAUS8	physical	20360068
GCN1_HUMAN	GCN1L1	physical	20360068
TACC2_HUMAN	TACC2	physical	20360068
BASI_HUMAN	BSG	physical	20360068
NEDD1_HUMAN	NEDD1	physical	20360068
GNAI2_HUMAN	GNAI2	physical	20360068
GNAI3_HUMAN	GNAI3	physical	20360068
HAUS4_HUMAN	HAUS4	physical	20360068
TPM1_HUMAN	TPM1	physical	20360068
LRRF2_HUMAN	LRRFIP2	physical	20360068
HAUS7_HUMAN	HAUS7	physical	20360068
BEGIN_HUMAN	BEGAIN	physical	20360068
HAUS1_HUMAN	HAUS1	physical	20360068
TIF1B_HUMAN	TRIM28	physical	20360068
GBB2_HUMAN	GNB2	physical	20360068
PCM1_HUMAN	PCM1	physical	26496610
FXR2_HUMAN	FXR2	physical	26496610
CP131_HUMAN	CEP131	physical	26496610
HAUS5_HUMAN	HAUS5	physical	26496610
HAUS6_HUMAN	HAUS6	physical	26496610
HAUS2_HUMAN	HAUS2	physical	26496610
HAUS7_HUMAN	HAUS7	physical	26496610
CEP72_HUMAN	CEP72	physical	26496610
BEGIN_HUMAN	BEGAIN	physical	26496610
HAUS3_HUMAN	HAUS3	physical	26496610
SNIP1_HUMAN	SNIP1	physical	26496610
HAUS8_HUMAN	HAUS8	physical	26496610
HAUS1_HUMAN	HAUS1	physical	26496610

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HAUS4_MOUSE

Related Literatures of Post-Translational Modification