GAL3_YEAST - dbPTM
GAL3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GAL3_YEAST
UniProt AC P13045
Protein Name Protein GAL3
Gene Name GAL3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 520
Subcellular Localization
Protein Description The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease..
Protein Sequence MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MNTNVPIF
-------CCCCCCCC
14.5822814378
233PhosphorylationFRPKLKATPFKFPQL
ECCCCCCCCCCCCCC
27.8919779198
391PhosphorylationQRAKHVYSESLRVLK
HHHHHHHHHHHHHHH
21.4419779198
428PhosphorylationLMNESQASCDKLYEC
HHCHHHHHCCCEEEC
18.4028889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GAL3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GAL3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GAL3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GAL80_YEASTGAL80physical
9050845
GAL80_YEASTGAL80physical
9111326
GAL80_YEASTGAL80physical
8628318
GAL80_YEASTGAL80physical
9670023
GAL80_YEASTGAL80physical
16219783
GAL1_YEASTGAL1genetic
2199310
GAL10_YEASTGAL10genetic
2199310
PGM2_YEASTPGM2genetic
2199310
GAL7_YEASTGAL7genetic
2199310
G6PI_YEASTPGI1genetic
2199310
SSN3_YEASTSSN3genetic
10805731
GAL1_YEASTGAL1genetic
2071013
GAL80_YEASTGAL80genetic
18245852
GAL80_YEASTGAL80physical
18245852
URE2_YEASTURE2physical
18467557
PUS3_YEASTDEG1genetic
19061648
GCN20_YEASTGCN20genetic
19061648
NOP3_YEASTNPL3genetic
19061648
CWC26_YEASTBUD13genetic
19061648
MED31_YEASTSOH1genetic
19061648
LEO1_YEASTLEO1genetic
19061648
TMA23_YEASTTMA23genetic
19061648
DSS1_YEASTDSS1genetic
19061648
RPA49_YEASTRPA49genetic
19061648
FKBP_YEASTFPR1genetic
19061648
IMB4_YEASTKAP123genetic
19061648
HOS2_YEASTHOS2genetic
19061648
GIS2_YEASTGIS2genetic
19061648
GAL80_YEASTGAL80physical
18952899
SSD1_YEASTSSD1genetic
20093466
YEW7_YEASTYER137Cgenetic
20093466
SNF6_YEASTSNF6genetic
20093466
THIK_YEASTPOT1genetic
20093466
SAC1_YEASTSAC1genetic
20093466
YL149_YEASTYLR149Cgenetic
20093466
AP1_YEASTYAP1genetic
20959818
LEO1_YEASTLEO1genetic
20959818
HOS2_YEASTHOS2genetic
20959818
PPAD_YEASTDIA3genetic
21127252
GAL4_YEASTGAL4genetic
21589890
BLH1_YEASTLAP3genetic
21589890
GAL7_YEASTGAL7genetic
21589890
GAL80_YEASTGAL80physical
22302941
GAL3_YEASTGAL3physical
22302941
GAL80_YEASTGAL80genetic
22479149
GAL1_YEASTGAL1genetic
24785355
GAL80_YEASTGAL80genetic
24785355
GAL80_YEASTGAL80physical
25135592
YEW7_YEASTYER137Cgenetic
27708008
SNF6_YEASTSNF6genetic
27708008
THIK_YEASTPOT1genetic
27708008
MRT4_YEASTMRT4genetic
27708008
SAC1_YEASTSAC1genetic
27708008
REH1_YEASTREH1genetic
27708008
OXR1_YEASTOXR1genetic
27708008
GAL80_YEASTGAL80physical
28333434
GAL80_YEASTGAL80physical
26516093

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GAL3_YEAST

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Related Literatures of Post-Translational Modification

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