dbPTM

AST4_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AST4_DROME
UniProt AC	P10084
Protein Name	Achaete-scute complex protein T4
Gene Name	sc
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	345
Subcellular Localization
Protein Description	AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation..
Protein Sequence	MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEHFQLDEEDCTPDDEEILDYISLWQEQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of AST4_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AST4_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AST4_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AST4_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AST5_DROME	ac	genetic	16084506
AST5_DROME	ac	genetic	14704182
AST8_DROME	ase	genetic	20868489
ZEST_DROME	z	genetic	9003324
ACT1_DROME	Act5C	genetic	24190881
TAF9_DROME	e(y)1	genetic	9003324
SAYP_DROME	e(y)3	genetic	9003324
DA_DROME	da	genetic	24190881
DPN_DROME	dpn	genetic	8601486
CHN_DROME	chn	genetic	15703278
HAIR_DROME	h	genetic	8330537
HAIR_DROME	h	genetic	8524259
NFKB1_DROME	Rel	genetic	18000549
SUHW_DROME	su(Hw)	genetic	10207068
SUHW_DROME	su(Hw)	genetic	12783795
SUHW_DROME	su(Hw)	genetic	2558282
SUHW_DROME	su(Hw)	genetic	11085260
ESMD_DROME	E(spl)mdelta-HLH	genetic	12466194
ESMC_DROME	E(spl)mgamma-HLH	genetic	12466194
ESM7_DROME	E(spl)m7-HLH	genetic	12466194
GFI1_DROME	sens	genetic	16554363
GFI1_DROME	sens	genetic	24360277
GFI1_DROME	sens	genetic	10975525
MMD4_DROME	mod(mdg4)	genetic	12783795
MMD4_DROME	mod(mdg4)	genetic	9439572
MMD4_DROME	mod(mdg4)	genetic	10207068
SXL_DROME	Sxl	genetic	2124516
SXL_DROME	Sxl	genetic	14704182
ACT1_DROME	Act5C	physical	24190881
DA_DROME	da	physical	1915272
DA_DROME	da	physical	7623836
DA_DROME	da	physical	7651341
DORS_DROME	dl	physical	8453668
ACT2_DROME	Act42A	physical	24190881
EMC_DROME	emc	physical	7821225

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AST4_DROME

Related Literatures of Post-Translational Modification