| UniProt ID | GFI1_DROME | |
|---|---|---|
| UniProt AC | Q9N658 | |
| Protein Name | Zinc finger protein sens | |
| Gene Name | sens | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 541 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcription factor both necessary and sufficient for proper development of most cell types of the embryonic and adult peripheral nervous system (PNS). Essential component of the proneural Notch signaling pathway required for proper sensory organ precursor (SOP) differentiation. Correct expression requires expression of scalloped (sd). Repression of rough (ro) in R8 photoreceptor is an essential mechanism of R8 cell fate determination.. | |
| Protein Sequence | MNHLSPPPSPHSQQPSPAGLGCHGAALDKQWMQRASAFNTVIASAAAQKLNGRDLPFLYNPLLYSSALLWPQFLLSSATALGTPLTPMTPKSPASVVLGQRDRDFALTPEKEHELQMNNNNENSKQDYQEQDEDMPLNLSTKERITSDDSNRDQYHSSSNNSSRSSSSSEVEQLHPMTSLNVTPPPLSAVNLKSSSTPQQQRQRSQGNIIWSPASMCERSARREQYGLKMEEQGDEEEHQVDPIVRKFKYERRTASISSLQSPISSLSAPASNAVQDLEFEVAQQQLYAHRSAFMAGLTGNNLELLTQHLKLKSEQPQQQQQQHRIKDEQQQDNRSAAALMNLVAAAEFGYMRNQHQQPQQQQQQQLHHQQQPQQHQHQQQHPDSTATDVARRSSSSSSYQGENEEKRSGRNFQCKQCGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCLKAFSQSSNLITHMRKHTGYKPFGCHLCDQSFQRKVDLRRHRESRHEEAPPVEDLKPLKMEVSSSSC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 509 | Sumoylation | CDQSFQRKVDLRRHR CCHHHHHHHHHHHHH | 29.35 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GFI1_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GFI1_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GFI1_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| AST5_DROME | ac | genetic | 14665671 | |
| SCAL_DROME | sd | genetic | 12782275 | |
| AFF4_DROME | lilli | genetic | 17110483 | |
| DA_DROME | da | genetic | 16554363 | |
| ESC_DROME | esc | genetic | 21490066 | |
| HDAC1_DROME | Rpd3 | genetic | 21490066 | |
| EZ_DROME | E(z) | genetic | 21490066 | |
| HID_DROME | W | genetic | 12925597 | |
| PC_DROME | Pc | genetic | 21490066 | |
| HMPB_DROME | pb | genetic | 21490066 | |
| ANTP_DROME | Antp | genetic | 21490066 | |
| CAF1_DROME | Caf1 | genetic | 17110483 | |
| CAF1_DROME | Caf1 | genetic | 21490066 | |
| DL_DROME | Dl | genetic | 17110483 | |
| ESM8_DROME | E(spl)m8-HLH | genetic | 10975525 | |
| ROUGH_DROME | ro | genetic | 11709152 | |
| SUZ12_DROME | Su(z)12 | genetic | 21490066 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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