| UniProt ID | ROUGH_DROME | |
|---|---|---|
| UniProt AC | P10181 | |
| Protein Name | Homeobox protein rough | |
| Gene Name | ro | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 350 | |
| Subcellular Localization | Nucleus . Restricted to nuclei in the developing retina. | |
| Protein Description | Required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk. Repression of expression in R8 photoreceptor by senseless (sens) is an essential mechanism of R8 cell fate determination.. | |
| Protein Sequence | MQRHKVEIGSPDGSPGIKRSDSLDPIANTTILSVPQRPSSPRQFFERLYGHLETRSSENGEIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANGFMSSIMGQAATTMPPGGVTGGVAVGVGLNYYAAAATPAALPKDNTQDANFIDIDDQFQRQQQQKQQQQQQQQRRRETTTPINIC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of ROUGH_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ROUGH_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ROUGH_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ROUGH_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| AFF4_DROME | lilli | genetic | 17110483 | |
| WNTG_DROME | wg | genetic | 9271118 | |
| AMOS_DROME | amos | genetic | 8252627 | |
| AMOS_DROME | amos | genetic | 11861566 | |
| PTC_DROME | ptc | genetic | 11063695 | |
| ATO_DROME | ato | genetic | 11063695 | |
| OSA_DROME | osa | genetic | 9271118 | |
| OSA_DROME | osa | genetic | 11063695 | |
| GLAS_DROME | gl | genetic | 11063695 | |
| DL_DROME | Dl | genetic | 11063695 | |
| HLES_DROME | H | genetic | 11063695 | |
| HH_DROME | hh | genetic | 11063695 | |
| GROU_DROME | gro | genetic | 11063695 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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