HAIR_DROME - dbPTM
HAIR_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HAIR_DROME
UniProt AC P14003
Protein Name Protein hairy
Gene Name h
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 337
Subcellular Localization Nucleus.
Protein Description Pair-rule protein that regulates embryonic segmentation and adult bristle patterning. Transcriptional repressor of genes that require a bHLH protein for their transcription (e.g. the Fushi tarazu gene)..
Protein Sequence MVTGVTAANMTNVLGTAVVPAQLKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of HAIR_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseToporsQ9V8P9
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HAIR_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HAIR_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CTBP_DROMECtBPphysical
9892668
GROU_DROMEgrophysical
9892668
UBX_DROMEUbxgenetic
16455680
GROU_DROMEgrophysical
17898168
AST5_DROMEacgenetic
5445760
AST5_DROMEacgenetic
8330537
AST3_DROMEl(1)scgenetic
8330537
AMOS_DROMEamosgenetic
12702684
TOPRS_DROMEToporsgenetic
14871887
FTZ_DROMEftzgenetic
8524259
CTBP_DROMECtBPgenetic
9524128
GROU_DROMEgrogenetic
10973955
GROU_DROMEgrogenetic
18034187
SXL_DROMESxlgenetic
2124516
SIR2_DROMESir2physical
12086602
TOPRS_DROMEToporsphysical
14871887
HAIR_DROMEhphysical
14871887
CTBP_DROMECtBPphysical
21343912
CTBP_DROMECtBPphysical
9524128
GROU_DROMEgrophysical
10433905
GROU_DROMEgrophysical
10652276
GROU_DROMEgrophysical
11598015
GROU_DROMEgrophysical
12154126
GROU_DROMEgrophysical
16762837
GROU_DROMEgrophysical
17571073
GROU_DROMEgrophysical
19805071
GROU_DROMEgrophysical
8001118
GROU_DROMEgrophysical
8649374
GROU_DROMEgrophysical
9367988
GROU_DROMEgrophysical
21343912
GROU_DROMEgrophysical
9371806
GROU_DROMEgrophysical
9524128

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HAIR_DROME

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Related Literatures of Post-Translational Modification

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