| UniProt ID | ZEST_DROME | |
|---|---|---|
| UniProt AC | P09956 | |
| Protein Name | Regulatory protein zeste | |
| Gene Name | z | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 575 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.. | |
| Protein Sequence | MSAQGEGGGAGGSGGGGAGSDGGGNAGQSSTGSGTVAVTNGGNSSAKNQLPLTPRFTAEEKEVLYTLFHLHEEVIDIKHRKKQRNKYSVRETWDKIVKDFNSHPHVSAMRNIKQIQKFWLNSRLRKQYPYRDGSSSNLSSGSAKISSVSVSVASAVPQQQQQQHHQQHDSVKVEPEYQISPDASEHNPQADTFDEIEMDANDVSEIDEDPMEQQQQQQQEAQAQAQAQAQAQAQVQSAAAEMQKMQQVNAVAAAAAANATMINTHQINVDQISAEKLTLNDLLHFKTARPREEIILIKHPEATATQIHTIPTQAQQHPMATITAGGYNQQIISEIKPQQITLAQYQAQQQQQAQAQAQAQAQAQAQAQAQAQAQAQAQQLAQQQLAAAQHQQLAAAVQVHHQQQQQQQAAVAVQQQQAAAAAAVKMQLTAATPTFTFSALPTVTAATTVPAAVPVPVATASSGSANSVAVNTSTASSVSINNTSLGGGGGNGATNSSATAADSFEERMNYFKIREAELRCKEQQLATEAKRIELNKAQDELKYMKEVHRLRVEELTMKIRILQKEEEQLRKCSTS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of ZEST_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZEST_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZEST_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZEST_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| POXM_DROME | Poxm | physical | 14605208 | |
| RL38_DROME | RpL38 | genetic | 8144360 | |
| WHITE_DROME | w | genetic | 2991082 | |
| WHITE_DROME | w | genetic | 8536972 | |
| TAF9_DROME | e(y)1 | genetic | 7851770 | |
| SAYP_DROME | e(y)3 | genetic | 7851770 | |
| HP1_DROME | Su(var)205 | genetic | 8536972 | |
| PSC_DROME | Psc | genetic | 1905661 | |
| PSC_DROME | Psc | genetic | 1968409 | |
| PSC_DROME | Psc | genetic | 7635282 | |
| PSC_DROME | Psc | genetic | 7687213 | |
| SUZ2_DROME | Su(z)2 | genetic | 1905661 | |
| SUZ2_DROME | Su(z)2 | genetic | 1968409 | |
| SUZ2_DROME | Su(z)2 | genetic | 2511424 | |
| SUZ2_DROME | Su(z)2 | genetic | 4217331 | |
| SUZ2_DROME | Su(z)2 | genetic | 7635282 | |
| SUZ2_DROME | Su(z)2 | genetic | 19528329 | |
| EZ_DROME | E(z) | genetic | 1977656 | |
| EZ_DROME | E(z) | genetic | 4217331 | |
| EZ_DROME | E(z) | genetic | 2511424 | |
| EZ_DROME | E(z) | genetic | 8152422 | |
| EZ_DROME | E(z) | genetic | 8413234 | |
| SCM_DROME | Scm | genetic | 8625848 | |
| SCM_DROME | Scm | genetic | 9755199 | |
| ENY2_DROME | e(y)2 | genetic | 7851770 | |
| METK_DROME | Sam-S | genetic | 4217331 | |
| ZEST_DROME | z | physical | 1732733 | |
| ZEST_DROME | z | physical | 2118108 | |
| ZEST_DROME | z | physical | 8491196 | |
| RL371_DROME | RpL37a | physical | 25242320 | |
| SUHW_DROME | su(Hw) | physical | 23861668 | |
| MMD4_DROME | mod(mdg4) | physical | 23861668 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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