dbPTM

RUS1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RUS1_HUMAN
UniProt AC	Q96GQ5
Protein Name	RUS1 family protein C16orf58
Gene Name	C16orf58
Organism	Homo sapiens (Human).
Sequence Length	468
Subcellular Localization	Membrane Single-pass membrane protein .
Protein Description
Protein Sequence	MADDAGLETPLCSEQFGSGEARGCRAAADGSLQWEVGGWRWWGLSRAFTVKPEGRDAGEVGASGAPSPPLSGLQAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATQAVLLGIGVGNAKATVSAATATWLVKDSTGMLGRIVFAWWKGSKLDCNAKQWRLFADILNDVAMFLEIMAPVYPICFTMTVSTSNLAKCIVSVAGGATRAALTVHQARRNNMADVSAKDSSQETLVNLAGLLVSLLMLPLVSGCPGFSLGCFFFLTALHIYANYRAVRALVMETLNEGRLRLVLKHYLQRGEVLDPTAANRMEPLWTGFWPAPSLSLGVPLHRLVSSVFELQQLVEGHQESYLLCWDQSQNQVQVVLNQKAGPKTILRAATHGLMLGALQGDGPLPAELEELRNRVRAGPKKESWVVVKETHEVLDMLFPKFLKGLQDAGWKTEKHQLEVDEWRATWLLSPEKKVL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
51 (in isoform 1)	Ubiquitination	-	21890473
171 (in isoform 2)	Ubiquitination	-	21890473
174 (in isoform 2)	Ubiquitination	-	21890473
185 (in isoform 2)	Ubiquitination	-	21890473
203 (in isoform 2)	Ubiquitination	-	21890473
204 (in isoform 2)	Ubiquitination	-	21890473
297 (in isoform 1)	Ubiquitination	-	21890473
433 (in isoform 1)	Ubiquitination	-	21890473
436 (in isoform 1)	Ubiquitination	-	21890473
444	Acetylation	GLQDAGWKTEKHQLE HHHHCCCCCCEEEEC	25953088
447 (in isoform 1)	Ubiquitination	-	21890473
465 (in isoform 1)	Ubiquitination	-	21890473
466 (in isoform 1)	Ubiquitination	-	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RUS1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RUS1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RUS1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BMPR2_HUMAN	BMPR2	physical	28514442
CEGT_HUMAN	UGCG	physical	28514442
EPHB3_HUMAN	EPHB3	physical	28514442
CANT1_HUMAN	CANT1	physical	28514442
LAP4A_HUMAN	LAPTM4A	physical	28514442
UBB_HUMAN	UBB	physical	28514442
DFNA5_HUMAN	DFNA5	physical	28514442
TR19L_HUMAN	RELT	physical	28514442
MP3B2_HUMAN	MAP1LC3B2	physical	28514442
BMR1A_HUMAN	BMPR1A	physical	28514442
GLMN_HUMAN	GLMN	physical	28514442
NFIP1_HUMAN	NDFIP1	physical	28514442
TNFL9_HUMAN	TNFSF9	physical	28514442
AVR2A_HUMAN	ACVR2A	physical	28514442
RAB9A_HUMAN	RAB9A	physical	28514442
PTPRS_HUMAN	PTPRS	physical	28514442
FGFR1_HUMAN	FGFR1	physical	28514442
PLIN3_HUMAN	PLIN3	physical	28514442
LRP10_HUMAN	LRP10	physical	28514442
TM214_HUMAN	TMEM214	physical	28514442
CD320_HUMAN	CD320	physical	28514442
AVR2B_HUMAN	ACVR2B	physical	28514442
RN149_HUMAN	RNF149	physical	28514442
SDCB1_HUMAN	SDCBP	physical	28514442
RAB21_HUMAN	RAB21	physical	28514442
INGR1_HUMAN	IFNGR1	physical	28514442
STX10_HUMAN	STX10	physical	28514442
PAQR1_HUMAN	ADIPOR1	physical	28514442
MARC1_HUMAN	MARC1	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RUS1_HUMAN

Related Literatures of Post-Translational Modification