MAGAA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAGAA_HUMAN
• UniProt AC: P43363
• Protein Name: Melanoma-associated antigen 10
• Gene Name: MAGEA10
• Organism: Homo sapiens (Human).
• Sequence Length: 369
• Subcellular Localization: Nucleus .
• Protein Description: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression..
• Protein Sequence: MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Phosphorylation	PSSFPSSSSSSSSSC CCCCCCCCCCCCCCC	38.28	-
57	Phosphorylation	SSFPSSSSSSSSSCY CCCCCCCCCCCCCCE	35.87	-
58	Phosphorylation	SFPSSSSSSSSSCYP CCCCCCCCCCCCCEE	35.87	-
59	Phosphorylation	FPSSSSSSSSSCYPL CCCCCCCCCCCCEEC	35.87	-
116	Phosphorylation	SSSQKEESPSTLQVL CCCCCCCCCCCEEEC	25.83	20815410
118	Phosphorylation	SQKEESPSTLQVLPD CCCCCCCCCEEECCC	51.53	25002506
119	Phosphorylation	QKEESPSTLQVLPDS CCCCCCCCEEECCCC	25.29	20815410
126	Phosphorylation	TLQVLPDSESLPRSE CEEECCCCCCCCHHH	27.43	26699800
128	Phosphorylation	QVLPDSESLPRSEID EECCCCCCCCHHHHH	47.85	26699800
269	Ubiquitination	LIYGEPRKLLTQDWV HHHCCCCHHCCHHHH	59.57	21906983
280	Phosphorylation	QDWVQENYLEYRQVP HHHHHHCCCHHCCCC	10.52	-
283	Phosphorylation	VQENYLEYRQVPGSD HHHCCCHHCCCCCCC	12.07	-
310	Phosphorylation	HAEIRKMSLLKFLAK HHHHHHHHHHHHHHH	33.32	24719451
313	Ubiquitination	IRKMSLLKFLAKVNG HHHHHHHHHHHHHCC	43.56	-
317	Ubiquitination	SLLKFLAKVNGSDPR HHHHHHHHHCCCCCC	38.08	-
325	Phosphorylation	VNGSDPRSFPLWYEE HCCCCCCCCCCHHHH	36.28	29523821

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAGAA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAGAA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAGAA_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KAT2A_HUMAN	KAT2A	physical	26186194
KAT2B_HUMAN	KAT2B	physical	26186194
NCOA2_HUMAN	NCOA2	physical	26186194
CSR2B_HUMAN	CSRP2BP	physical	26186194
YETS2_HUMAN	YEATS2	physical	26186194
POTEF_HUMAN	POTEF	physical	26186194
ACTB_HUMAN	ACTB	physical	26186194
DDX42_HUMAN	DDX42	physical	26186194
CUX1_HUMAN	CUX1	physical	26186194
CASP_HUMAN	CUX1	physical	26186194
SLF1_HUMAN	ANKRD32	physical	26186194
TIF1A_HUMAN	TRIM24	physical	26186194
PHF8_HUMAN	PHF8	physical	26186194
SATB2_HUMAN	SATB2	physical	26186194
NRIP1_HUMAN	NRIP1	physical	26186194
CCD12_HUMAN	CCDC12	physical	26186194
RS4X_HUMAN	RPS4X	physical	26186194
QSER1_HUMAN	QSER1	physical	26186194
ERI1_HUMAN	ERI1	physical	26186194
FOXJ2_HUMAN	FOXJ2	physical	26186194
PESC_HUMAN	PES1	physical	26186194
TPM2_HUMAN	TPM2	physical	26186194
TADA3_HUMAN	TADA3	physical	26186194
F216A_HUMAN	FAM216A	physical	26186194
PKN1_HUMAN	PKN1	physical	26186194
PO2F1_HUMAN	POU2F1	physical	26186194
CC106_HUMAN	CCDC106	physical	26186194
CCHCR_HUMAN	CCHCR1	physical	26186194
CRTC3_HUMAN	CRTC3	physical	26186194
GT2D1_HUMAN	GTF2IRD1	physical	26186194
VPS72_HUMAN	VPS72	physical	26186194
KAT2A_HUMAN	KAT2A	physical	26496610
PON2_HUMAN	PON2	physical	26496610
XPO1_HUMAN	XPO1	physical	26496610
SCO2_HUMAN	SCO2	physical	26496610
NCOA2_HUMAN	NCOA2	physical	26496610
MTCL1_HUMAN	MTCL1	physical	26496610
F216A_HUMAN	FAM216A	physical	26496610
FOXJ2_HUMAN	FOXJ2	physical	26496610
MTUS1_HUMAN	MTUS1	physical	26496610
SLAI2_HUMAN	SLAIN2	physical	26496610
QSER1_HUMAN	QSER1	physical	26496610
FOXJ2_HUMAN	FOXJ2	physical	28514442
NCOA2_HUMAN	NCOA2	physical	28514442
F216A_HUMAN	FAM216A	physical	28514442
KAT2A_HUMAN	KAT2A	physical	28514442
KAT2B_HUMAN	KAT2B	physical	28514442
PO2F1_HUMAN	POU2F1	physical	28514442
NRIP1_HUMAN	NRIP1	physical	28514442
ERI1_HUMAN	ERI1	physical	28514442
QSER1_HUMAN	QSER1	physical	28514442
POTEF_HUMAN	POTEF	physical	28514442
PHF8_HUMAN	PHF8	physical	28514442
SLF1_HUMAN	ANKRD32	physical	28514442
PKN1_HUMAN	PKN1	physical	28514442
CCHCR_HUMAN	CCHCR1	physical	28514442
SATB2_HUMAN	SATB2	physical	28514442
PESC_HUMAN	PES1	physical	28514442
CC106_HUMAN	CCDC106	physical	28514442
CRTC3_HUMAN	CRTC3	physical	28514442
GT2D1_HUMAN	GTF2IRD1	physical	28514442
YETS2_HUMAN	YEATS2	physical	28514442
TPM2_HUMAN	TPM2	physical	28514442
TADA3_HUMAN	TADA3	physical	28514442
CUX1_HUMAN	CUX1	physical	28514442
CASP_HUMAN	CUX1	physical	28514442
DDX42_HUMAN	DDX42	physical	28514442
CSR2B_HUMAN	CSRP2BP	physical	28514442
RS4X_HUMAN	RPS4X	physical	28514442
ZZZ3_HUMAN	ZZZ3	physical	28514442
CDC6_HUMAN	CDC6	physical	28514442
ACTBL_HUMAN	ACTBL2	physical	28514442
ACTB_HUMAN	ACTB	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.