F216A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F216A_HUMAN
• UniProt AC: Q8WUB2
• Protein Name: Protein FAM216A
• Gene Name: FAM216A
• Organism: Homo sapiens (Human).
• Sequence Length: 273
• Protein Sequence: MLGQLLPHTARGLGAAEMPGQGPGSDWTERSSSAEPPAVAGTEGGGGGSAGYSCYQNSKGSDRIKDGYKVNSHIAKLQELWKTPQNQTIHLSKSMMEASFFKHPDLTTGQKRYLCSIAKIYNANYLKMLMKRQYMHVLQHSSQKPGVLTHHRSRLSSRYSQKQHYPCTTWRHQLEREDSGSSDIAAASAPEMLIQHSLWRPVRNKEGIKTGYASKTRCKSLKIFRRPRKLFMQTVSSDDSESHMSEEKKEEDLLNNFMQSMSIEEQGEHLMLT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Ubiquitination	LGAAEMPGQGPGSDW CCCCCCCCCCCCCCC	43.71	22817900
32	Phosphorylation	SDWTERSSSAEPPAV CCCCCCCCCCCCCCC	39.53	24114839
33	Phosphorylation	DWTERSSSAEPPAVA CCCCCCCCCCCCCCC	37.59	24114839
59	Ubiquitination	YSCYQNSKGSDRIKD CCCCCCCCCCCCCCC	70.73	21963094
68	Phosphorylation	SDRIKDGYKVNSHIA CCCCCCCCEEHHHHH	23.15	22817900
69	Ubiquitination	DRIKDGYKVNSHIAK CCCCCCCEEHHHHHH	40.23	29967540
76	Ubiquitination	KVNSHIAKLQELWKT EEHHHHHHHHHHHCC	50.53	29967540
82	Ubiquitination	AKLQELWKTPQNQTI HHHHHHHCCCCCCEE	64.05	29967540
83	Phosphorylation	KLQELWKTPQNQTIH HHHHHHCCCCCCEEE	20.65	29978859
88	Phosphorylation	WKTPQNQTIHLSKSM HCCCCCCEEEECHHH	20.22	29978859
92	Phosphorylation	QNQTIHLSKSMMEAS CCCEEEECHHHHHHH	14.44	29978859
111	Ubiquitination	PDLTTGQKRYLCSIA CCCCCCCHHHHHHHH	44.34	29967540
116	Phosphorylation	GQKRYLCSIAKIYNA CCHHHHHHHHHHHCH	24.00	-
162	Ubiquitination	LSSRYSQKQHYPCTT HHHHHCCCCCCCCCH	32.85	-
179	Phosphorylation	HQLEREDSGSSDIAA HHHHCCCCCCCCCHH	35.50	-
197	Phosphorylation	PEMLIQHSLWRPVRN CHHHHHHCCCCCCCC	17.16	24719451
205	Ubiquitination	LWRPVRNKEGIKTGY CCCCCCCCCCCCCCC	46.91	-
209	Ubiquitination	VRNKEGIKTGYASKT CCCCCCCCCCCCCCH	46.91	29967540
215	Ubiquitination	IKTGYASKTRCKSLK CCCCCCCCHHCCCCC	31.64	-
222	Acetylation	KTRCKSLKIFRRPRK CHHCCCCCCCCCCHH	47.06	7667075
234	Phosphorylation	PRKLFMQTVSSDDSE CHHHHEEECCCCCCH	15.57	29523821
236	Phosphorylation	KLFMQTVSSDDSESH HHHEEECCCCCCHHH	31.28	29523821
237	Phosphorylation	LFMQTVSSDDSESHM HHEEECCCCCCHHHC	40.89	29523821
240	Phosphorylation	QTVSSDDSESHMSEE EECCCCCCHHHCCHH	46.09	-
245	Phosphorylation	DDSESHMSEEKKEED CCCHHHCCHHHHHHH	36.86	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F216A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F216A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F216A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of F216A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.