GA45G_HUMAN - dbPTM
GA45G_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GA45G_HUMAN
UniProt AC O95257
Protein Name Growth arrest and DNA damage-inducible protein GADD45 gamma
Gene Name GADD45G
Organism Homo sapiens (Human).
Sequence Length 159
Subcellular Localization
Protein Description Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK..
Protein Sequence MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of GA45G_HUMAN !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GA45G_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GA45G_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GA45G_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
G45IP_HUMANGADD45GIP1physical
12716909
PCNA_HUMANPCNAphysical
11022036
CDN1A_HUMANCDKN1Aphysical
11022036
ESR1_HUMANESR1physical
10872826
PPARA_HUMANPPARAphysical
10872826
PPARD_HUMANPPARDphysical
10872826
PPARG_HUMANPPARGphysical
10872826
RARA_HUMANRARAphysical
10872826
RXRA_HUMANRXRAphysical
10872826
PCNA_HUMANPCNAphysical
10455148
CDN1A_HUMANCDKN1Aphysical
10455148
CDK1_HUMANCDK1physical
12124778
CCNB1_HUMANCCNB1physical
12124778
MIDN_HUMANMIDNphysical
21900206
MYOME_HUMANPDE4DIPphysical
21900206
ZN579_HUMANZNF579physical
21900206
UT14A_HUMANUTP14Aphysical
21900206
CRIP2_HUMANCRIP2physical
21900206
EF1A1_HUMANEEF1A1physical
21900206
EIF3G_HUMANEIF3Gphysical
21900206
SNF5_HUMANSMARCB1physical
21900206
EZH2_HUMANEZH2physical
21900206
PDIA4_HUMANPDIA4physical
21900206
DDAH2_HUMANDDAH2physical
21900206
KAIN_HUMANSERPINA4physical
21900206
RDH13_HUMANRDH13physical
21900206
TRM2A_HUMANTRMT2Aphysical
21900206
PHAX_HUMANPHAXphysical
21900206
LC7L2_HUMANLUC7L2physical
21900206
HAP1_HUMANHAP1physical
15383276
KAT5_HUMANKAT5physical
15383276
UT14A_HUMANUTP14Aphysical
15383276
RBM48_HUMANRBM48physical
15383276
LUC7L_HUMANLUC7Lphysical
15383276
LRIF1_HUMANLRIF1physical
15383276
PIAS4_HUMANPIAS4physical
15383276
MED31_HUMANMED31physical
15383276
LC7L2_HUMANLUC7L2physical
15383276
A4_HUMANAPPphysical
21832049
SHLB2_HUMANSH3GLB2physical
21988832
SGK1_HUMANSGK1physical
21988832
SHLB1_HUMANSH3GLB1physical
21988832
HPT_HUMANHPphysical
21988832
AF1L1_HUMANAFAP1L1physical
25416956
CE57L_HUMANCEP57L1physical
25416956

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GA45G_HUMAN

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Related Literatures of Post-Translational Modification

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