F131B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F131B_HUMAN
• UniProt AC: Q86XD5
• Protein Name: Protein FAM131B
• Gene Name: FAM131B
• Organism: Homo sapiens (Human).
• Sequence Length: 332
• Protein Sequence: MDSTSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLIASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEEEDAGCRDLESLSPREDPEMSTALSRKVSDVTSSGVQSFDEEEGEANN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2 (in isoform 2)	Myristoylation	-	61.70	20213681
47	Phosphorylation	LPKLKRNSNAYGIGA HHHHHHCCCCCCHHH	27.20	28857561
58	Phosphorylation	GIGALAKSSFSGISR CHHHHHHHCCCCCCH	30.89	28102081
59	Phosphorylation	IGALAKSSFSGISRS HHHHHHHCCCCCCHH	23.79	26670566
61	Phosphorylation	ALAKSSFSGISRSMK HHHHHCCCCCCHHHH	36.85	23312004
64	Phosphorylation	KSSFSGISRSMKDHV HHCCCCCCHHHHHCC	23.10	28102081
66	Phosphorylation	SFSGISRSMKDHVTK CCCCCCHHHHHCCCC	24.32	-
72	Phosphorylation	RSMKDHVTKPTAMGQ HHHHHCCCCCCCCCC	28.08	-
75	Phosphorylation	KDHVTKPTAMGQGRV HHCCCCCCCCCCCHH	30.72	-
102	Phosphorylation	PAVQPQHSHESVRRD CCCCCCCCCHHHHCC	24.57	27732954
105	Phosphorylation	QPQHSHESVRRDTDA CCCCCCHHHHCCCCC	18.59	26670566
110	Phosphorylation	HESVRRDTDAYSDLS CHHHHCCCCCCCCCC	22.25	25072903
113	Phosphorylation	VRRDTDAYSDLSDGE HHCCCCCCCCCCCHH	12.91	25072903
114	Phosphorylation	RRDTDAYSDLSDGEK HCCCCCCCCCCCHHH	33.52	24114839
117	Phosphorylation	TDAYSDLSDGEKEAR CCCCCCCCCHHHHHH	48.86	25072903
145	Phosphorylation	ATLMAWSSMDGEDMS HHHHHHHCCCCCCCC	15.36	18510355
220	Phosphorylation	ASPATGSYLGPAFDD CCCCCCCCCCCCCCC	19.61	-
295	Phosphorylation	AGCRDLESLSPREDP CCCCCHHHCCCCCCH	41.25	24719451
297	Phosphorylation	CRDLESLSPREDPEM CCCHHHCCCCCCHHH	31.06	24076635
309	Phosphorylation	PEMSTALSRKVSDVT HHHHHHHHHHHHHHC	27.82	29802988
313	Phosphorylation	TALSRKVSDVTSSGV HHHHHHHHHHCCCCC	29.42	21406692
316	Phosphorylation	SRKVSDVTSSGVQSF HHHHHHHCCCCCCCC	23.36	21406692
317	Phosphorylation	RKVSDVTSSGVQSFD HHHHHHCCCCCCCCC	25.58	21406692
318	Phosphorylation	KVSDVTSSGVQSFDE HHHHHCCCCCCCCCH	33.35	21406692
322	Phosphorylation	VTSSGVQSFDEEEGE HCCCCCCCCCHHHCC	32.05	24076635
342	Ubiquitination	----------------- -----------------		21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F131B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F131B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F131B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NCOA1_HUMAN	NCOA1	physical	28514442
TOP2A_HUMAN	TOP2A	physical	28514442
GNPAT_HUMAN	GNPAT	physical	28514442
CDC6_HUMAN	CDC6	physical	28514442
QCR6_HUMAN	UQCRH	physical	28514442
TASOR_HUMAN	FAM208A	physical	28514442
FNTB_HUMAN	FNTB	physical	28514442
AURKA_HUMAN	AURKA	physical	28514442
URFB1_HUMAN	UHRF1BP1	physical	28514442
BIG2_HUMAN	ARFGEF2	physical	28514442
GDC_HUMAN	SLC25A16	physical	28514442
MYO9B_HUMAN	MYO9B	physical	28514442
ORNT1_HUMAN	SLC25A15	physical	28514442
CNDH2_HUMAN	NCAPH2	physical	28514442
CQ080_HUMAN	C17orf80	physical	28514442
VPP2_HUMAN	ATP6V0A2	physical	28514442
TTF2_HUMAN	TTF2	physical	28514442
MICU1_HUMAN	MICU1	physical	28514442
ADT3_HUMAN	SLC25A6	physical	28514442
SEH1_HUMAN	SEH1L	physical	28514442
PLK1_HUMAN	PLK1	physical	28514442
ADCK1_HUMAN	ADCK1	physical	28514442
CAHD1_HUMAN	CACHD1	physical	28514442
MBLC2_HUMAN	MBLAC2	physical	28514442
VPP1_HUMAN	ATP6V0A1	physical	28514442
TIM29_HUMAN	C19orf52	physical	28514442
F213A_HUMAN	FAM213A	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.