dbPTM

MYO9B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MYO9B_HUMAN
UniProt AC	Q13459
Protein Name	Unconventional myosin-IXb
Gene Name	MYO9B
Organism	Homo sapiens (Human).
Sequence Length	2157
Subcellular Localization	Cytoplasm, cell cortex . Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton . In undifferentiated cells colocalizes with F-actin in the cell periphery while in differentiated cells its localization is cytoplasmic with the highest levels in the p
Protein Description	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. [PubMed: 9490638 Also acts as a GTPase activator for RHOA]
Protein Sequence	MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGAQSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKSKGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRVSPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGERSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENAVSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRESVFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHVGYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPLKLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSVKEAGSS ------CCHHHCCCC	53.88	22814378
2	Phosphorylation	------MSVKEAGSS ------CCHHHCCCC	53.88	20068231
4	Ubiquitination	----MSVKEAGSSGR ----CCHHHCCCCCC	51.65	-
8	Phosphorylation	MSVKEAGSSGRREQA CCHHHCCCCCCHHHH	36.35	20068231
9	Phosphorylation	SVKEAGSSGRREQAA CHHHCCCCCCHHHHH	35.09	20068231
17	Phosphorylation	GRREQAAYHLHIYPQ CCHHHHHHEEEEECC	14.13	27642862
22	Phosphorylation	AAYHLHIYPQLSTTE HHHEEEEECCCCCCC	3.68	-
26	Phosphorylation	LHIYPQLSTTESQAS EEEECCCCCCCCCCC	28.21	24247654
27	Phosphorylation	HIYPQLSTTESQASC EEECCCCCCCCCCCC	43.08	27251275
40	Malonylation	SCRVTATKDSTTSDV CCEEEECCCCCCHHH	47.41	26320211
40	Ubiquitination	SCRVTATKDSTTSDV CCEEEECCCCCCHHH	47.41	-
45	Phosphorylation	ATKDSTTSDVIKDAI ECCCCCCHHHHHHHH	29.93	24114839
49	Ubiquitination	STTSDVIKDAIASLR CCCHHHHHHHHHHCC	40.74	-
83	Phosphorylation	WVLDANDSPVHRVLL EEECCCCCCCEEEEE	28.73	25159151
117	Phosphorylation	QERNADGTIKYVHMQ EEECCCCCEEEEEHH	18.16	24719451
120	Phosphorylation	NADGTIKYVHMQLVA CCCCCEEEEEHHHHH	7.55	24719451
132	Phosphorylation	LVAQATATRRLVERG HHHHHHHHHHHHHCC	16.39	24719451
198	Ubiquitination	FLPIYNPKYVKMYEN CCCCCCHHHEEECCC	60.07	-
201	Ubiquitination	IYNPKYVKMYENQQL CCCHHHEEECCCCCC	32.45	-
262	Ubiquitination	CLTALSQKGYASGVE HHHHHHHCCCCCCCC	50.98	-
307	Phosphorylation	IQVSYLESGIVRGAV EEEEHHCCCCCCHHH	31.09	-
322	Ubiquitination	VEKYLLEKSRLVSQE HHHHHHHHHCCCCCC	40.62	-
339	Phosphorylation	ERNYHVFYYLLLGVS HHHHHHHHHHHHCCC	7.66	-
378	Acetylation	IEDGEDLKHDFERLK CCCCCCHHHHHHHHH	54.15	25953088
378	Ubiquitination	IEDGEDLKHDFERLK CCCCCCHHHHHHHHH	54.15	-
410	Phosphorylation	AVLSAILYLGNVTYK HHHHHHHHHCCCCCC	13.37	22210691
415	Phosphorylation	ILYLGNVTYKKRATG HHHHCCCCCCCCCCC	33.35	22210691
416	Phosphorylation	LYLGNVTYKKRATGR HHHCCCCCCCCCCCC	15.38	22210691
439	Phosphorylation	PEVLDTLSQLLKVKR HHHHHHHHHHHHHHH	22.37	24719451
603	Phosphorylation	ESNFPHATSQTLLAK CCCCCCCCHHHHHHH	20.52	24247654
642	Phosphorylation	HFAGKVKYQIKDFRE HHCCCCCEEHHHHHH	20.61	23403867
715	Sulfoxidation	RAEKAAGMSSPGAQS HHHHHCCCCCCCHHC	2.84	30846556
716	Phosphorylation	AEKAAGMSSPGAQSH HHHHCCCCCCCHHCC	32.25	29255136
717	Phosphorylation	EKAAGMSSPGAQSHP HHHCCCCCCCHHCCH	20.61	29255136
722	Phosphorylation	MSSPGAQSHPEELPR CCCCCHHCCHHHCCC	40.24	23927012
732	Phosphorylation	EELPRGASTPSEKLY HHCCCCCCCCCHHHH	43.61	26074081
733	Phosphorylation	ELPRGASTPSEKLYR HCCCCCCCCCHHHHH	30.24	24719451
735	Phosphorylation	PRGASTPSEKLYRDL CCCCCCCCHHHHHHH	47.67	26074081
737	Ubiquitination	GASTPSEKLYRDLHN CCCCCCHHHHHHHHH	55.97	-
739	Phosphorylation	STPSEKLYRDLHNQM CCCCHHHHHHHHHHH	17.10	-
746	Sulfoxidation	YRDLHNQMIKSIKGL HHHHHHHHHHHHCCC	5.17	30846556
748	Ubiquitination	DLHNQMIKSIKGLPW HHHHHHHHHHCCCCC	40.56	-
762	Phosphorylation	WQGEDPRSLLQSLSR CCCCCHHHHHHHHHH	38.53	23403867
766	Phosphorylation	DPRSLLQSLSRLQKP CHHHHHHHHHHCCCC	28.43	26462736
768	Phosphorylation	RSLLQSLSRLQKPRA HHHHHHHHHCCCCCE	35.87	23403867
796	Phosphorylation	IPKNLLDSKSLKLII CCHHHCCCCCCEEHH	24.90	27174698
797	Ubiquitination	PKNLLDSKSLKLIIS CHHHCCCCCCEEHHH	60.52	-
798	O-linked_Glycosylation	KNLLDSKSLKLIISM HHHCCCCCCEEHHHC	34.39	30379171
798	Phosphorylation	KNLLDSKSLKLIISM HHHCCCCCCEEHHHC	34.39	27174698
804	Phosphorylation	KSLKLIISMTLHDRT CCCEEHHHCCCCCCC	9.94	27174698
806	Phosphorylation	LKLIISMTLHDRTTK CEEHHHCCCCCCCHH	17.72	27174698
814	Phosphorylation	LHDRTTKSLLHLHKK CCCCCHHHHHHHHHC	33.79	20873877
844	Ubiquitination	KLLEALGKAEPFFIR HHHHHHHCCCCHHHH	50.88	-
875	Phosphorylation	LVLQQLRYTGMLETV HHHHHHHHHCCEEEE	19.08	-
876	Phosphorylation	VLQQLRYTGMLETVR HHHHHHHHCCEEEEE	15.07	-
881	Phosphorylation	RYTGMLETVRIRRSG HHHCCEEEEEEECCC	15.89	-
887	Phosphorylation	ETVRIRRSGYSAKYT EEEEEECCCCCEEEE	32.03	21406692
889	Phosphorylation	VRIRRSGYSAKYTFQ EEEECCCCCEEEEEC	13.50	21406692
890	Phosphorylation	RIRRSGYSAKYTFQD EEECCCCCEEEEECH	23.08	21406692
893	Phosphorylation	RSGYSAKYTFQDFTE CCCCCEEEEECHHHH	16.71	20886841
918	Phosphorylation	QPCREVISTLLEKMK HHHHHHHHHHHHHCC	20.41	23403867
919	Phosphorylation	PCREVISTLLEKMKI HHHHHHHHHHHHCCC	25.00	23403867
923	Ubiquitination	VISTLLEKMKIDKRN HHHHHHHHCCCCCCC	45.52	-
931	Phosphorylation	MKIDKRNYQIGKTKV CCCCCCCCCCCCEEE	12.92	25599653
935	Ubiquitination	KRNYQIGKTKVFLKE CCCCCCCCEEEHHHH	46.96	-
936	Phosphorylation	RNYQIGKTKVFLKET CCCCCCCEEEHHHHH	27.51	25599653
941	Ubiquitination	GKTKVFLKETERQAL CCEEEHHHHHHHHHH	51.64	-
951	Phosphorylation	ERQALQETLHREVVR HHHHHHHHHHHHHHH	18.20	-
965	Phosphorylation	RKILLLQSWFRMVLE HHHHHHHHHHHHHHH	28.31	27251275
992	Phosphorylation	TIQACWRSYRVRRAL HHHHHHHHHHHHHHH	7.87	22210691
993	Phosphorylation	IQACWRSYRVRRALE HHHHHHHHHHHHHHH	12.45	22210691
1027	Phosphorylation	LYRHQKQSIIRLQSL HHHHHHHHHHHHHHH	27.33	24719451
1033	Phosphorylation	QSIIRLQSLCRGHLQ HHHHHHHHHHHHHHH	33.75	24719451
1043	Phosphorylation	RGHLQRKSFSQMISE HHHHHHHHHHHHHHH	32.11	23401153
1045	Phosphorylation	HLQRKSFSQMISEKQ HHHHHHHHHHHHHHH	26.40	30266825
1049	Phosphorylation	KSFSQMISEKQKAEE HHHHHHHHHHHHHHH	33.14	28102081
1099	Phosphorylation	EDGGHLASEPEVQPS CCCCCCCCCCCCCCC	61.11	25921289
1106	Phosphorylation	SEPEVQPSDRSPLEH CCCCCCCCCCCCCCC	28.68	26074081
1109	Phosphorylation	EVQPSDRSPLEHSSP CCCCCCCCCCCCCCC	38.54	29255136
1114	Phosphorylation	DRSPLEHSSPEKEAP CCCCCCCCCCCCCCC	37.91	29255136
1115	Phosphorylation	RSPLEHSSPEKEAPS CCCCCCCCCCCCCCC	38.70	29255136
1122	Phosphorylation	SPEKEAPSPEKTLPP CCCCCCCCCCCCCCC	53.38	23401153
1126	Phosphorylation	EAPSPEKTLPPQKTV CCCCCCCCCCCCCCC	42.72	26074081
1132	Phosphorylation	KTLPPQKTVAAESHE CCCCCCCCCCCCCCC	15.32	26074081
1137	Phosphorylation	QKTVAAESHEKVPSS CCCCCCCCCCCCCCH	32.02	25002506
1143	Phosphorylation	ESHEKVPSSREKRES CCCCCCCCHHHHHHH	45.04	21712546
1144	Phosphorylation	SHEKVPSSREKRESR CCCCCCCHHHHHHHH	38.09	25002506
1150	Phosphorylation	SSREKRESRRQRGLE CHHHHHHHHHHHHHH	36.47	-
1183	Phosphorylation	REPSRRVTQEQGVSL CCCCHHCHHHHCCCH	25.28	23401153
1189	Phosphorylation	VTQEQGVSLLEDKKE CHHHHCCCHHHCHHC	33.78	27422710
1237	Phosphorylation	VSEETEKTLPSGSPR CCHHHHCCCCCCCCC	37.35	23403867
1240	Phosphorylation	ETEKTLPSGSPRPGQ HHHCCCCCCCCCCCC	55.82	30266825
1242	Phosphorylation	EKTLPSGSPRPGQLE HCCCCCCCCCCCCCC	23.29	30266825
1252	Phosphorylation	PGQLERPTSLALDSR CCCCCCCCCEEECCC	42.46	28348404
1253	Phosphorylation	GQLERPTSLALDSRV CCCCCCCCEEECCCC	17.83	28348404
1258	Phosphorylation	PTSLALDSRVSPPAP CCCEEECCCCCCCCC	35.12	23403867
1261	Phosphorylation	LALDSRVSPPAPGSA EEECCCCCCCCCCCC	24.85	19664994
1267	Phosphorylation	VSPPAPGSAPETPED CCCCCCCCCCCCCCC	39.32	29255136
1271	Phosphorylation	APGSAPETPEDKSKP CCCCCCCCCCCCCCC	30.80	29255136
1276	Phosphorylation	PETPEDKSKPCGSPR CCCCCCCCCCCCCCC	54.90	27422710
1281	Phosphorylation	DKSKPCGSPRVQEKP CCCCCCCCCCCCCCC	19.09	27273156
1290	Phosphorylation	RVQEKPDSPGGSTQI CCCCCCCCCCCCHHH	33.69	29255136
1294	Phosphorylation	KPDSPGGSTQIQRYL CCCCCCCCHHHHHHH	24.05	30266825
1295	Phosphorylation	PDSPGGSTQIQRYLD CCCCCCCHHHHHHHC	32.73	23927012
1300	Phosphorylation	GSTQIQRYLDAERLA CCHHHHHHHCHHHHH	7.80	30576142
1308	Phosphorylation	LDAERLASAVELWRG HCHHHHHHHHHHHCC	37.12	28857561
1323	Phosphorylation	KKLVAAASPSAMLSQ CCHHEECCHHHHHHC	18.05	25159151
1325	Phosphorylation	LVAAASPSAMLSQSL HHEECCHHHHHHCCC	24.66	25159151
1329	Phosphorylation	ASPSAMLSQSLDLSD CCHHHHHHCCCCCHH	12.49	23401153
1331	Phosphorylation	PSAMLSQSLDLSDRH HHHHHHCCCCCHHHH	22.07	30278072
1335	Phosphorylation	LSQSLDLSDRHRATG HHCCCCCHHHHHCCC	32.06	23403867
1341	Phosphorylation	LSDRHRATGAALTPT CHHHHHCCCCCCCCC	27.58	28176443
1346	Phosphorylation	RATGAALTPTEERRT HCCCCCCCCCHHHCC	24.36	19664994
1348	Phosphorylation	TGAALTPTEERRTSF CCCCCCCCHHHCCCC	45.29	25159151
1353	Phosphorylation	TPTEERRTSFSTSDV CCCHHHCCCCCHHHH	40.10	29255136
1354	Phosphorylation	PTEERRTSFSTSDVS CCHHHCCCCCHHHHH	18.52	29255136
1356	Phosphorylation	EERRTSFSTSDVSKL HHHCCCCCHHHHHHH	27.11	23401153
1357	Phosphorylation	ERRTSFSTSDVSKLL HHCCCCCHHHHHHHH	27.25	23927012
1358	Phosphorylation	RRTSFSTSDVSKLLP HCCCCCHHHHHHHHH	34.51	25159151
1361	Phosphorylation	SFSTSDVSKLLPSLA CCCHHHHHHHHHHHH	23.68	23927012
1366	Phosphorylation	DVSKLLPSLAKAQPA HHHHHHHHHHHCCCC	40.71	-
1376	Phosphorylation	KAQPAAETTDGERSA HCCCCCCCCCCCCCC	26.01	28851738
1377	Phosphorylation	AQPAAETTDGERSAK CCCCCCCCCCCCCCC	33.25	28851738
1382	Phosphorylation	ETTDGERSAKKPAVQ CCCCCCCCCCCCCCC	39.89	28985074
1397	Phosphorylation	KKKPGDASSLPDAGL CCCCCCHHHCCCCCC	36.83	28176443
1398	Phosphorylation	KKPGDASSLPDAGLS CCCCCHHHCCCCCCC	45.71	28176443
1405	Phosphorylation	SLPDAGLSPGSQVDS HCCCCCCCCCCCCCC	26.71	29255136
1408	Phosphorylation	DAGLSPGSQVDSKST CCCCCCCCCCCCHHH	30.34	29255136
1412	Phosphorylation	SPGSQVDSKSTFKRL CCCCCCCCHHHHHHH	29.65	28176443
1429	Phosphorylation	HKTKDKKYSLEGAEE CCCCCCCCCCCCHHH	24.99	29978859
1430	Phosphorylation	KTKDKKYSLEGAEEL CCCCCCCCCCCHHHH	28.91	29978859
1454	Ubiquitination	LEATTMKKGLEAPSG EEEECCCCCCCCCCC	58.88	-
1474	Acetylation	AAGEKRTKEPGGKGK CCCCCCCCCCCCCCC	66.98	7669985
1479	Acetylation	RTKEPGGKGKKNRNV CCCCCCCCCCCCCCC	73.75	26051181
1481	Acetylation	KEPGGKGKKNRNVKI CCCCCCCCCCCCCEE	50.81	26051181
1490	Ubiquitination	NRNVKIGKITVSEKW CCCCEEEEEECCHHH	38.38	-
1492	Phosphorylation	NVKIGKITVSEKWRE CCEEEEEECCHHHHH	22.82	28060719
1494	Phosphorylation	KIGKITVSEKWRESV EEEEEECCHHHHHHH	25.47	28857561
1496	Ubiquitination	GKITVSEKWRESVFR EEEECCHHHHHHHHH	44.00	-
1569	Phosphorylation	YKDLMENYQIVVSNL HHHHHHHEEEEEECC	6.06	-
1574	Phosphorylation	ENYQIVVSNLATERG HHEEEEEECCCHHCC	18.42	-
1578	Phosphorylation	IVVSNLATERGQKDT EEEECCCHHCCCCHH	29.40	-
1682	Phosphorylation	HKIQSHCSYTYGRKG HHHHHHCCCCCCCCC	18.32	28857561
1683	Phosphorylation	KIQSHCSYTYGRKGE HHHHHCCCCCCCCCC	14.91	21552520
1684	Phosphorylation	IQSHCSYTYGRKGEP HHHHCCCCCCCCCCC	11.82	27642862
1685	Phosphorylation	QSHCSYTYGRKGEPG HHHCCCCCCCCCCCC	13.50	27642862
1752	Phosphorylation	ELRQALQTDPAAVKL HHHHHHHCCCCHHHC	44.81	21406692
1861	Phosphorylation	LLRCPDNSDPLTSMK HHCCCCCCCCCCCHH	48.24	29083192
1865	Phosphorylation	PDNSDPLTSMKDVLK CCCCCCCCCHHHHHH	31.96	29083192
1866	Phosphorylation	DNSDPLTSMKDVLKI CCCCCCCCHHHHHHH	31.36	29083192
1874	Phosphorylation	MKDVLKITTCVEMLI HHHHHHHHHHHHHHH	16.74	26437602
1875	Phosphorylation	KDVLKITTCVEMLIK HHHHHHHHHHHHHHH	20.30	30387612
1910	Phosphorylation	SIAFRRLSLLRQNAP HHHHHHHHHHHHCCC	24.44	23312004
1925	Phosphorylation	WPLKLGFSSPYEGVL CCEECCCCCCCCCCC	28.71	21945579
1926	Phosphorylation	PLKLGFSSPYEGVLN CEECCCCCCCCCCCC	29.28	21945579
1928	Phosphorylation	KLGFSSPYEGVLNKS ECCCCCCCCCCCCCC	27.54	21945579
1935	Phosphorylation	YEGVLNKSPKTRDIQ CCCCCCCCCCCCCCC	30.47	23401153
1972	Phosphorylation	ILIERIQSIKEEKED HHHHHHHHHHHHHCC	33.00	23401153
1981	Phosphorylation	KEEKEDITYRLPELD HHHHCCCCEECCCCC	18.21	30576142
1982	Phosphorylation	EEKEDITYRLPELDP HHHCCCCEECCCCCC	15.53	24702127
1992	Phosphorylation	PELDPRGSDEENLDS CCCCCCCCCCCCCCC	43.03	19664994
1993	Phosphorylation	ELDPRGSDEENLDSE CCCCCCCCCCCCCCC	70.79	18669648
1999	Phosphorylation	SDEENLDSETSASTE CCCCCCCCCCCCCHH	46.04	30266825
2001	Phosphorylation	EENLDSETSASTESL CCCCCCCCCCCHHHH	33.28	30266825
2002	Phosphorylation	ENLDSETSASTESLL CCCCCCCCCCHHHHH	19.03	30266825
2004	Phosphorylation	LDSETSASTESLLEE CCCCCCCCHHHHHHH	32.26	30266825
2005	Phosphorylation	DSETSASTESLLEER CCCCCCCHHHHHHHH	29.34	30266825
2007	Phosphorylation	ETSASTESLLEERAG CCCCCHHHHHHHHCC	38.04	28450419
2033	Phosphorylation	LPCPGAPTPSPLPTV CCCCCCCCCCCCCCC	35.55	25850435
2035	Phosphorylation	CPGAPTPSPLPTVAA CCCCCCCCCCCCCCC	41.36	25850435
2039	Phosphorylation	PTPSPLPTVAAPPRR CCCCCCCCCCCCCCC	30.38	25850435
2049	Phosphorylation	APPRRRPSSFVTVRV CCCCCCCCCCEEEEE	34.30	29255136
2050	Phosphorylation	PPRRRPSSFVTVRVK CCCCCCCCCEEEEEE	26.81	29255136
2053	Phosphorylation	RRPSSFVTVRVKTPR CCCCCCEEEEEECCC	10.69	29978859
2055	Methylation	PSSFVTVRVKTPRRT CCCCEEEEEECCCCC	18.17	54557487
2058	Phosphorylation	FVTVRVKTPRRTPIM CEEEEEECCCCCCCC	21.12	28555341
2062	Phosphorylation	RVKTPRRTPIMPTAN EEECCCCCCCCCCCC	20.60	28555341
2067	Phosphorylation	RRTPIMPTANIKLPP CCCCCCCCCCCCCCC	18.24	24260401
2109	Phosphorylation	RRPDQIHSVYITPGA CCCCCCCEEEECCCC	20.46	29978859
2111	Phosphorylation	PDQIHSVYITPGADL CCCCCEEEECCCCCC	11.33	27050516
2113	Phosphorylation	QIHSVYITPGADLPV CCCEEEECCCCCCCC	9.66	28060719
2140	Phosphorylation	PPGAKRRYSDPPTYC CCCCCCCCCCCCCCC	22.81	23663014
2141	Phosphorylation	PGAKRRYSDPPTYCL CCCCCCCCCCCCCCC	41.66	23401153
2145	Phosphorylation	RRYSDPPTYCLPPAS CCCCCCCCCCCCCCC	32.05	23663014
2146	Phosphorylation	RYSDPPTYCLPPASG CCCCCCCCCCCCCCC	9.58	28270605

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MYO9B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MYO9B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MYO9B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Disease
OMIM Disease
609753	Celiac disease 4 (CELIAC4)
Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MYO9B_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1267; THR-1271; SER-1290AND SER-1992, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1290; SER-1354 ANDSER-1992, AND MASS SPECTROMETRY.	19369195 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1267; THR-1271 ANDTHR-1348, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-716; SER-1290; SER-1354AND SER-1992, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-716; SER-1290; SER-1323;SER-1405 AND SER-1992, AND MASS SPECTROMETRY.	18691976 [Abstract]
"Phosphorylation analysis of primary human T lymphocytes usingsequential IMAC and titanium oxide enrichment."; Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J.; J. Proteome Res. 7:5167-5176(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1290, AND MASSSPECTROMETRY.	19367720 [Abstract]
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1267; THR-1271; SER-1290AND THR-1346, AND MASS SPECTROMETRY.	18088087 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1354, AND MASSSPECTROMETRY.	19007248 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1267 AND THR-1271, ANDMASS SPECTROMETRY.	17081983 [Abstract]