CSK2B_DROME - dbPTM
CSK2B_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CSK2B_DROME
UniProt AC P08182
Protein Name Casein kinase II subunit beta
Gene Name CkIIbeta
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 235
Subcellular Localization
Protein Description Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit..
Protein Sequence MSSSEEVSWVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDNPLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGEAMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSLAYQIQLQAAANFKMPLRAQRGQPPKDEEPENNADTVPKRL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSSSEEVSW
------CCCHHHHHH
42.4419429919
3Phosphorylation-----MSSSEEVSWV
-----CCCHHHHHHH
40.2319429919
4Phosphorylation----MSSSEEVSWVT
----CCCHHHHHHHH
30.3919429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
2SPhosphorylationKinaseCSK2BP08182
PhosphoELM
2SPhosphorylationKinaseCKIIBETA-GPS
3SPhosphorylationKinaseCSK2BP08182
PhosphoELM
3SPhosphorylationKinaseCKIIBETA-GPS
4SPhosphorylationKinaseCSK2BP08182
PhosphoELM
4SPhosphorylationKinaseCKIIBETA-GPS

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CSK2B_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CSK2B_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
WDR12_DROMECG6724physical
14605208
SISA_DROMEsisAphysical
14605208
CSK2A_DROMECkIIalphaphysical
14605208
MLR_DROMEMlc2physical
14605208
DTX_DROMEdxphysical
14605208
SAP30_DROMESap30physical
14605208
SIR2_DROMESir2physical
14605208
RSMB_DROMESmBphysical
14605208
DEI_DROMEtxphysical
14605208
RL18A_DROMERpL18Aphysical
14605208
PHLP_DROMECG7650physical
14605208
RS8_DROMERpS8physical
14605208
TBB1_DROMEbetaTub56Dphysical
14605208
PDFR_DROMEPdfrgenetic
16242403
PER_DROMEperphysical
24013921
CSK2B_DROMECkIIbetaphysical
11874456
TIM_DROMEtimphysical
24013921
SSL_DROMESslphysical
11874456
CLOCK_DROMEClkphysical
24013921
CSK2A_DROMECkIIalphaphysical
19144847
CSK2A_DROMECkIIalphaphysical
24013921
CSK2A_DROMECkIIalphaphysical
10329473

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CSK2B_DROME

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Related Literatures of Post-Translational Modification

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