UniProt ID | CSK2B_DROME | |
---|---|---|
UniProt AC | P08182 | |
Protein Name | Casein kinase II subunit beta | |
Gene Name | CkIIbeta | |
Organism | Drosophila melanogaster (Fruit fly). | |
Sequence Length | 235 | |
Subcellular Localization | ||
Protein Description | Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.. | |
Protein Sequence | MSSSEEVSWVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDNPLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGEAMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSLAYQIQLQAAANFKMPLRAQRGQPPKDEEPENNADTVPKRL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSSSEEVSW ------CCCHHHHHH | 42.44 | 19429919 | |
3 | Phosphorylation | -----MSSSEEVSWV -----CCCHHHHHHH | 40.23 | 19429919 | |
4 | Phosphorylation | ----MSSSEEVSWVT ----CCCHHHHHHHH | 30.39 | 19429919 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
2 | S | Phosphorylation | Kinase | CSK2B | P08182 | PhosphoELM |
2 | S | Phosphorylation | Kinase | CKIIBETA | - | GPS |
3 | S | Phosphorylation | Kinase | CSK2B | P08182 | PhosphoELM |
3 | S | Phosphorylation | Kinase | CKIIBETA | - | GPS |
4 | S | Phosphorylation | Kinase | CSK2B | P08182 | PhosphoELM |
4 | S | Phosphorylation | Kinase | CKIIBETA | - | GPS |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSK2B_DROME !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSK2B_DROME !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
WDR12_DROME | CG6724 | physical | 14605208 | |
SISA_DROME | sisA | physical | 14605208 | |
CSK2A_DROME | CkIIalpha | physical | 14605208 | |
MLR_DROME | Mlc2 | physical | 14605208 | |
DTX_DROME | dx | physical | 14605208 | |
SAP30_DROME | Sap30 | physical | 14605208 | |
SIR2_DROME | Sir2 | physical | 14605208 | |
RSMB_DROME | SmB | physical | 14605208 | |
DEI_DROME | tx | physical | 14605208 | |
RL18A_DROME | RpL18A | physical | 14605208 | |
PHLP_DROME | CG7650 | physical | 14605208 | |
RS8_DROME | RpS8 | physical | 14605208 | |
TBB1_DROME | betaTub56D | physical | 14605208 | |
PDFR_DROME | Pdfr | genetic | 16242403 | |
PER_DROME | per | physical | 24013921 | |
CSK2B_DROME | CkIIbeta | physical | 11874456 | |
TIM_DROME | tim | physical | 24013921 | |
SSL_DROME | Ssl | physical | 11874456 | |
CLOCK_DROME | Clk | physical | 24013921 | |
CSK2A_DROME | CkIIalpha | physical | 19144847 | |
CSK2A_DROME | CkIIalpha | physical | 24013921 | |
CSK2A_DROME | CkIIalpha | physical | 10329473 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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