SISA_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SISA_DROME
• UniProt AC: Q9VZ09
• Protein Name: Protein sisterless A {ECO:0000312|EMBL:AAF48022.1}
• Gene Name: sisA
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 189
• Subcellular Localization: Nucleus .
• Protein Description: Involved in sex determination and dosage compensation. Required for proper expression of Sxl in embryonic somatic cells. Also has an essential function in the yolk nuclei. Involved in endoderm migration and midgut formation..
• Protein Sequence: MERSHLYLPTLSYAAMGHVYAPYRGSSSPALSTASSTSSKPEQIEELVSQQLHHLKMHYADEEQRYVDQMLLENPIVVERRAPPPLKTELAMDCRGSGSGSGSGSGSDVKDAQRQRAESCRKSRYNNKIKKAKLRFRHKFVSGQLKKSAVMLDTMRDVIAQAERQLLERGYPAATLERMRATFGLEMEQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of SISA_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SISA_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SISA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SISA_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RALA_DROME	Rala	physical	14605208
RG92B_DROME	RhoGAP92B	physical	14605208
TFP11_DROME	sip1	physical	14605208
AST4_DROME	sc	genetic	1900130
DPN_DROME	dpn	genetic	8601486
SXL_DROME	Sxl	genetic	10790394
SISA_DROME	sisA	physical	7651341
DA_DROME	da	physical	7651341
DPN_DROME	dpn	physical	7651341

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.