| UniProt ID | CSK2A_DROME | |
|---|---|---|
| UniProt AC | P08181 | |
| Protein Name | Casein kinase II subunit alpha | |
| Gene Name | CkIIalpha | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 336 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. May participate in Wnt signaling.. | |
| Protein Sequence | MTLPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 285 | Phosphorylation | RWERFVHSDNQHLVS HHHHHHCCCCCCCCC | 32.71 | 19429919 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSK2A_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSK2A_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSK2A_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CAD_DROME | cad | physical | 14605208 | |
| KPC3_DROME | Pkc98E | physical | 14605208 | |
| ELBOW_DROME | elB | physical | 14605208 | |
| CSK2C_DROME | CkIIbeta2 | physical | 15575970 | |
| MSIR6_DROME | Rbp6 | physical | 15575970 | |
| SXL_DROME | Sxl | physical | 14605208 | |
| PANG1_DROME | pan | physical | 17113388 | |
| PANG2_DROME | pan | physical | 17113388 | |
| CSK2B_DROME | CkIIbeta | physical | 22036573 | |
| CSK2C_DROME | CkIIbeta2 | physical | 22036573 | |
| CACT_DROME | cact | physical | 24086459 | |
| PDFR_DROME | Pdfr | genetic | 16242403 | |
| CSK2B_DROME | CkIIbeta | genetic | 21949709 | |
| ESM8_DROME | E(spl)m8-HLH | genetic | 16930955 | |
| KRAF1_DROME | phl | physical | 21262350 | |
| PER_DROME | per | physical | 24013921 | |
| CSK2B_DROME | CkIIbeta | physical | 24013921 | |
| CSK2B_DROME | CkIIbeta | physical | 24395637 | |
| CSK2B_DROME | CkIIbeta | physical | 10329473 | |
| CSK2B_DROME | CkIIbeta | physical | 11874456 | |
| TIM_DROME | tim | physical | 24013921 | |
| CSK2C_DROME | CkIIbeta2 | physical | 10329473 | |
| SSL_DROME | Ssl | physical | 11874456 | |
| CLOCK_DROME | Clk | physical | 24013921 | |
| CSK2A_DROME | CkIIalpha | physical | 1900838 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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