dbPTM

MSIR6_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MSIR6_DROME
UniProt AC	Q9VVE5
Protein Name	RNA-binding protein Musashi homolog Rbp6 {ECO:0000250\|UniProtKB:Q920Q6, ECO:0000303\|PubMed:8417324}
Gene Name	Rbp6 {ECO:0000303\|PubMed:8417324}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	369
Subcellular Localization	Cytoplasm .
Protein Description	RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity)..
Protein Sequence	MDIKIEQQQQQQQVELGPCSPSEVPNDPGKMFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHELDGKKVDPKVAFPRRAHPKMVTRTKKIFVGGLSAPTTLEDVKSYFEQFGPIEDAMLMFDKQTNRHRGFGFVTFQSEDVVDKVCEIHFHEINNKMVECKKAQPKEVMLPANLAKTRAAGRSAYDNIMWGLGTLPEGFPAAAYAAYAAGRGYSGYPSFGLPYPTVDLTNGQLTPNNNTPLLTQALSVMNNYQAAAAAAHSYGPSASPHAAAANTATRQGFPSTNSPGPTIDMYSSAAADNVGYVQATSPQPSGFPIAVSRAPLNYSPIYSLNFAMANI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	QVELGPCSPSEVPND CCCCCCCCCCCCCCC	34.30	27794539
126	Phosphorylation	KIFVGGLSAPTTLED EEEECCCCCCCCHHH	35.16	27794539
129	Phosphorylation	VGGLSAPTTLEDVKS ECCCCCCCCHHHHHH	43.67	27794539
130	Phosphorylation	GGLSAPTTLEDVKSY CCCCCCCCHHHHHHH	27.39	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MSIR6_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MSIR6_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MSIR6_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ORB2_DROME	orb2	physical	26638074
SMG_DROME	smg	physical	26638074

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MSIR6_DROME

Related Literatures of Post-Translational Modification