dbPTM

WDR12_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WDR12_DROME
UniProt AC	Q9VKQ3
Protein Name	Ribosome biogenesis protein WDR12 homolog {ECO:0000255\|HAMAP-Rule:MF_03029}
Gene Name	CG6724
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	420
Subcellular Localization	Nucleus, nucleolus . Nucleus, nucleoplasm .
Protein Description	Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit..
Protein Sequence	MDVDNGEGQVQVHLKTKQEHYAVPDVPYAIDGTVTTVELNTFVNALLRQKDGSSDTDFDFLVFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKARGKWILSGCYDNTLNLWTNKGKHILTISGHTAPIKAVDWISLDEETGRFVSTSQDQTAMLWQWNVGSNSVECVSVCKGHERGVDSVSVSPDGLRFATGSWDTMLKVWSAELDDAVEGSSKRMKESGVRTPKITLQGHRESVSAVQWMDATTLLTGSWDHTLKVWDLSLEGIKTEISTNKSIFDASYSKLNRLILTASADKNLRLYDPRTNQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGAYDNQNKLWDCRSPKAPLYDLLGHGEKVLDIDWSNPKYIVSGGVDNTVRVFKSRKALAEEAETK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of WDR12_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WDR12_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WDR12_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WDR12_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
IF6_DROME	eIF6	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WDR12_DROME

Related Literatures of Post-Translational Modification