| UniProt ID | TSN2_HUMAN | |
|---|---|---|
| UniProt AC | O60636 | |
| Protein Name | Tetraspanin-2 | |
| Gene Name | TSPAN2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 221 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.. | |
| Protein Sequence | MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 27 | Phosphorylation | LLFWLAGSAVIAFGL HHHHHHHHHHHHHHH | 17.47 | - | |
| 139 | N-linked_Glycosylation | LKDRGKGNGTLITFH HHHCCCCCCEEEEEE | 43.70 | UniProtKB CARBOHYD | |
| 139 | N-linked_Glycosylation | LKDRGKGNGTLITFH HHHCCCCCCEEEEEE | 43.70 | 19349973 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TSN2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TSN2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TSN2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| GRB2_HUMAN | GRB2 | physical | 25814554 | |
| P55G_HUMAN | PIK3R3 | physical | 25814554 | |
| CREB3_HUMAN | CREB3 | physical | 21516116 | |
| SNX13_HUMAN | SNX13 | physical | 28514442 | |
| SNX14_HUMAN | SNX14 | physical | 28514442 | |
| FPRP_HUMAN | PTGFRN | physical | 28514442 | |
| ZDHC6_HUMAN | ZDHHC6 | physical | 28514442 | |
| TSN3_HUMAN | TSPAN3 | physical | 28514442 | |
| REEP6_HUMAN | REEP6 | physical | 28514442 | |
| TSN15_HUMAN | TSPAN15 | physical | 28514442 | |
| CD032_HUMAN | C4orf32 | physical | 28514442 | |
| HSDL1_HUMAN | HSDL1 | physical | 28514442 | |
| MTCH1_HUMAN | MTCH1 | physical | 28514442 | |
| PRAF3_HUMAN | ARL6IP5 | physical | 28514442 | |
| CD63_HUMAN | CD63 | physical | 28514442 | |
| LCLT1_HUMAN | LCLAT1 | physical | 28514442 | |
| DGLB_HUMAN | DAGLB | physical | 28514442 | |
| MBOA5_HUMAN | LPCAT3 | physical | 28514442 | |
| LEG3_HUMAN | LGALS3 | physical | 28514442 | |
| ARF6_HUMAN | ARF6 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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