| UniProt ID | TFDP3_HUMAN | |
|---|---|---|
| UniProt AC | Q5H9I0 | |
| Protein Name | Transcription factor Dp family member 3 | |
| Gene Name | TFDP3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 405 | |
| Subcellular Localization | Nucleus. Cytoplasm. Translocates to the nucleus on heterodimerization with E2F family members. | |
| Protein Description | Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.. | |
| Protein Sequence | MAKYVSLTEANEELKVLMDENQTSRPVAVHTSTVNPLGKQLLPKTFGQSSVNIDQQVVIGMPQRPAASNIPVVGSPNPPSTHFASQNQHSYSSPPWAGQHNRKGEKNGMGLCRLSMKVWETVQRKGTTSCQEVVGELVAKFRAASNHASPNESAYDVKNIKRRTYDALNVLMAMNIISREKKKIKWIGLTTNSAQNCQNLRVERQKRLERIKQKQSELQQLILQQIAFKNLVLRNQYVEEQVSQRPLPNSVIHVPFIIISSSKKTVINCSISDDKSEYLFKFNSSFEIHDDTEVLMWMGMTFGLESGSCSAEDLKMARNLVPKALEPYVTEMAQGTFGGVFTTAGSRSNGTWLSASDLTNIAIGMLATSSGGSQYSGSRVETPAVEEEEEEDNNDDDLSENDEDD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 39 | Ubiquitination | STVNPLGKQLLPKTF CCCCCCHHHCCCCCC | 45.51 | 22817900 | |
| 44 | Ubiquitination | LGKQLLPKTFGQSSV CHHHCCCCCCCCCCC | 57.36 | 22817900 | |
| 121 | Phosphorylation | LSMKVWETVQRKGTT HHHHHHHHHHHHCCC | 13.26 | 30576142 | |
| 127 | Phosphorylation | ETVQRKGTTSCQEVV HHHHHHCCCCHHHHH | 20.69 | 30576142 | |
| 128 | Phosphorylation | TVQRKGTTSCQEVVG HHHHHCCCCHHHHHH | 35.85 | 22210691 | |
| 129 | Phosphorylation | VQRKGTTSCQEVVGE HHHHCCCCHHHHHHH | 17.40 | 22210691 | |
| 164 | Phosphorylation | VKNIKRRTYDALNVL HHCHHHHHHHHHHHH | 29.77 | 21214269 | |
| 165 | Phosphorylation | KNIKRRTYDALNVLM HCHHHHHHHHHHHHH | 9.45 | 24043423 | |
| 330 | Phosphorylation | KALEPYVTEMAQGTF HHHHHHHHHHCCCCC | 17.75 | 30576142 | |
| 342 | Phosphorylation | GTFGGVFTTAGSRSN CCCCEEEECCCCCCC | 17.21 | 30576142 | |
| 346 | Phosphorylation | GVFTTAGSRSNGTWL EEEECCCCCCCCCEE | 30.03 | 30576142 | |
| 351 | Phosphorylation | AGSRSNGTWLSASDL CCCCCCCCEEEHHHH | 27.73 | 19690332 | |
| 354 | Phosphorylation | RSNGTWLSASDLTNI CCCCCEEEHHHHCCC | 19.79 | 19690332 | |
| 356 | Phosphorylation | NGTWLSASDLTNIAI CCCEEEHHHHCCCCE | 29.76 | 19690332 | |
| 359 | Phosphorylation | WLSASDLTNIAIGML EEEHHHHCCCCEEEE | 29.57 | 19690332 | |
| 376 | Phosphorylation | SSGGSQYSGSRVETP CCCCCCCCCCCEECC | 23.74 | - | |
| 378 | Phosphorylation | GGSQYSGSRVETPAV CCCCCCCCCEECCCC | 27.49 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TFDP3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TFDP3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TFDP3_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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