| UniProt ID | SRC64_DROME | |
|---|---|---|
| UniProt AC | P00528 | |
| Protein Name | Tyrosine-protein kinase Src64B | |
| Gene Name | Src64B | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 552 | |
| Subcellular Localization | ||
| Protein Description | May play a role in the development of neural tissue and smooth muscle.. | |
| Protein Sequence | MGNKCCSKRQDQELALAYPTGGYKKSDYTFGQTHINSSGGGNMGGVLGQKHNNGGSLDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 56 | Phosphorylation | QKHNNGGSLDSRYTP CCCCCCCCCCCCCCC | 30.33 | 25749252 | |
| 306 | Phosphorylation | FYGKWRNSIDVAVKT HCHHHHHHHHHHHHH | 16.16 | 27626673 | |
| 434 | Phosphorylation | RVIADDEYCPKQGSR EEEECCCCCCCCCCC | 22.50 | 25749252 | |
| 547 | Phosphorylation | SVTSEVPYREVQD-- CEEECCCCCCCCC-- | 25.28 | N.N. |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 434 | Y | Phosphorylation | Kinase | SRC64 | P00528 | PhosphoELM |
| 434 | Y | Phosphorylation | Kinase | SRC | - | GPS |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SRC64_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SRC64_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SRC64_DROME | Src64B | physical | 14605208 | |
| AT5F1_DROME | ATPsyn-b | physical | 14605208 | |
| G6PI_DROME | Pgi | physical | 14605208 | |
| RM24_DROME | mRpL24 | physical | 14605208 | |
| TBB1_DROME | betaTub56D | physical | 14605208 | |
| BTKL_DROME | Btk29A | genetic | 9660965 | |
| BTKL_DROME | Btk29A | genetic | 9660966 | |
| BTKL_DROME | Btk29A | genetic | 15979065 | |
| BTKL_DROME | Btk29A | genetic | 23644660 | |
| DRK_DROME | drk | genetic | 8930392 | |
| RHO1_DROME | Rho1 | genetic | 23644660 | |
| CADE_DROME | shg | genetic | 23644660 | |
| CAPZA_DROME | cpa | genetic | 23644660 | |
| EGFR_DROME | Egfr | genetic | 24788409 | |
| YAP1_DROME | yki | genetic | 23644660 | |
| SINA_DROME | sina | genetic | 8378088 | |
| RAS1_DROME | Ras85D | genetic | 8378088 | |
| RAS1_DROME | Ras85D | genetic | 24788409 | |
| JNK_DROME | bsk | genetic | 23644660 | |
| CSW_DROME | csw | genetic | 8930392 | |
| CAD96_DROME | Cad96Ca | physical | 24522188 | |
| RYK1_DROME | drl | physical | 23979591 | |
| SRC64_DROME | Src64B | physical | 15107833 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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