EMSY_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EMSY_HUMAN
• UniProt AC: Q7Z589
• Protein Name: BRCA2-interacting transcriptional repressor EMSY {ECO:0000312|HGNC:HGNC:18071}
• Gene Name: EMSY {ECO:0000312|HGNC:HGNC:18071}
• Organism: Homo sapiens (Human).
• Sequence Length: 1322
• Subcellular Localization: Nucleus . Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
• Protein Description: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors..
• Protein Sequence: MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MPVVWPTLLDLSRD -CCCCCHHHHHCCHH	25.00	20068231
12	Phosphorylation	WPTLLDLSRDECKRI CHHHHHCCHHHHHHH	37.03	20068231
28	Phosphorylation	RKLELEAYAGVISAL HHHHHHHHHHHHHHH	8.43	-
110	Phosphorylation	MPRLVPQTAFTVTAN CCCCCCCEEEEEEHH	20.05	20068231
113	Phosphorylation	LVPQTAFTVTANAVA CCCCEEEEEEHHHHH	17.93	20068231
115	Phosphorylation	PQTAFTVTANAVANA CCEEEEEEHHHHHHH	15.90	20068231
129	Phosphorylation	AAIQHNASLPVPAET HHHHCCCCCCCCCCC	38.22	20068231
136	Phosphorylation	SLPVPAETGSKEVVC CCCCCCCCCCCEEEE	49.19	20068231
138	Phosphorylation	PVPAETGSKEVVCYS CCCCCCCCCEEEEEE	32.82	20068231
168	Phosphorylation	GSIATVKSPRPASPA CCEEEECCCCCCCCC	23.08	22167270
169	Phosphorylation	SIATVKSPRPASPAS CEEEECCCCCCCCCC	40.32	32142685
173	Phosphorylation	VKSPRPASPASNVVV ECCCCCCCCCCCEEE	24.55	22167270
176	Phosphorylation	PRPASPASNVVVLPS CCCCCCCCCEEEECC	33.28	30266825
177	Phosphorylation	RPASPASNVVVLPSG CCCCCCCCEEEECCC	32.48	32142685
183	Phosphorylation	SNVVVLPSGSTVYVK CCEEEECCCCEEEEE	41.01	23403867
185	Phosphorylation	VVVLPSGSTVYVKSV EEEECCCCEEEEEEE	21.02	23403867
186	Phosphorylation	VVLPSGSTVYVKSVS EEECCCCEEEEEEEE	21.27	23403867
188	Phosphorylation	LPSGSTVYVKSVSCS ECCCCEEEEEEEECC	11.40	23403867
191	Phosphorylation	GSTVYVKSVSCSDED CCEEEEEEEECCCCC	14.82	23312004
193	Phosphorylation	TVYVKSVSCSDEDEK EEEEEEEECCCCCCC	18.26	23403867
195	Phosphorylation	YVKSVSCSDEDEKPR EEEEEECCCCCCCCC	36.21	23403867
200	Acetylation	SCSDEDEKPRKRRRT ECCCCCCCCCCCCCC	63.54	26051181
207	Phosphorylation	KPRKRRRTNSSSSSP CCCCCCCCCCCCCCC	37.33	22167270
208	Phosphorylation	PRKRRRTNSSSSSPV CCCCCCCCCCCCCCE	37.78	32645325
209	Phosphorylation	RKRRRTNSSSSSPVV CCCCCCCCCCCCCEE	30.86	22167270
210	Phosphorylation	KRRRTNSSSSSPVVL CCCCCCCCCCCCEEE	35.99	30266825
211	Phosphorylation	RRRTNSSSSSPVVLK CCCCCCCCCCCEEEC	34.36	30266825
212	Phosphorylation	RRTNSSSSSPVVLKE CCCCCCCCCCEEECC	40.38	30266825
213	Phosphorylation	RTNSSSSSPVVLKEV CCCCCCCCCEEECCC	24.54	30266825
222	Phosphorylation	VVLKEVPKAVVPVSK EEECCCCCCEEECCC	60.01	32645325
224	Phosphorylation	LKEVPKAVVPVSKTI ECCCCCCEEECCCEE	6.62	32142685
228	O-linked_Glycosylation	PKAVVPVSKTITVPV CCCEEECCCEEEEEC	20.29	32574038
228	O-linked_Glycosylation	PKAVVPVSKTITVPV CCCEEECCCEEEEEC	20.29	20068230
229	Ubiquitination	KAVVPVSKTITVPVS CCEEECCCEEEEECC	44.15	29967540
230	O-linked_Glycosylation	AVVPVSKTITVPVSG CEEECCCEEEEECCC	17.86	20068230
230	Phosphorylation	AVVPVSKTITVPVSG CEEECCCEEEEECCC	17.86	23403867
230	Ubiquitination	AVVPVSKTITVPVSG CEEECCCEEEEECCC	17.86	29967540
232	O-linked_Glycosylation	VPVSKTITVPVSGSP EECCCEEEEECCCCH	24.80	20068230
232	Phosphorylation	VPVSKTITVPVSGSP EECCCEEEEECCCCH	24.80	23403867
234	Ubiquitination	VSKTITVPVSGSPKM CCCEEEEECCCCHHH	13.10	22505724
236	O-linked_Glycosylation	KTITVPVSGSPKMSN CEEEEECCCCHHHHH	27.73	32574038
236	O-linked_Glycosylation	KTITVPVSGSPKMSN CEEEEECCCCHHHHH	27.73	20068230
236	Phosphorylation	KTITVPVSGSPKMSN CEEEEECCCCHHHHH	27.73	30266825
238	O-linked_Glycosylation	ITVPVSGSPKMSNIM EEEECCCCHHHHHHH	17.53	20068230
238	Phosphorylation	ITVPVSGSPKMSNIM EEEECCCCHHHHHHH	17.53	23401153
239	Phosphorylation	TVPVSGSPKMSNIMQ EEECCCCHHHHHHHH	39.64	32142685
242	Phosphorylation	VSGSPKMSNIMQSIA CCCCHHHHHHHHHHH	29.36	24719451
243	Ubiquitination	SGSPKMSNIMQSIAN CCCHHHHHHHHHHHH	30.19	-
244	Ubiquitination	GSPKMSNIMQSIANS CCHHHHHHHHHHHHC	1.77	29967540
247	O-linked_Glycosylation	KMSNIMQSIANSLPP HHHHHHHHHHHCCCC	13.29	20068230
247	Phosphorylation	KMSNIMQSIANSLPP HHHHHHHHHHHCCCC	13.29	24719451
251	Phosphorylation	IMQSIANSLPPHMSP HHHHHHHCCCCCCCC	32.98	24719451
253	Phosphorylation	QSIANSLPPHMSPVK HHHHHCCCCCCCCEE	19.30	32142685
257	Phosphorylation	NSLPPHMSPVKITFT HCCCCCCCCEEEEEE	24.41	23186163
262	O-linked_Glycosylation	HMSPVKITFTKPSTQ CCCCEEEEEECCCCC	21.38	20068230
262	Phosphorylation	HMSPVKITFTKPSTQ CCCCEEEEEECCCCC	21.38	17924679
264	O-linked_Glycosylation	SPVKITFTKPSTQTT CCEEEEEECCCCCCC	33.14	20068230
267	O-linked_Glycosylation	KITFTKPSTQTTNTT EEEEECCCCCCCCCC	34.40	20068230
268	O-linked_Glycosylation	ITFTKPSTQTTNTTT EEEECCCCCCCCCCE	38.16	20068230
270	O-linked_Glycosylation	FTKPSTQTTNTTTQK EECCCCCCCCCCEEE	23.31	20068230
271	O-linked_Glycosylation	TKPSTQTTNTTTQKV ECCCCCCCCCCEEEE	22.28	32574038
271	O-linked_Glycosylation	TKPSTQTTNTTTQKV ECCCCCCCCCCEEEE	22.28	20068230
271	Phosphorylation	TKPSTQTTNTTTQKV ECCCCCCCCCCEEEE	22.28	-
273	Phosphorylation	PSTQTTNTTTQKVII CCCCCCCCCEEEEEE	29.18	17924679
274	O-linked_Glycosylation	STQTTNTTTQKVIIV CCCCCCCCEEEEEEE	29.33	20068230
274	Phosphorylation	STQTTNTTTQKVIIV CCCCCCCCEEEEEEE	29.33	17924679
276	Ubiquitination	QTTNTTTQKVIIVTT CCCCCCEEEEEEEEC	35.61	22505724
282	O-linked_Glycosylation	TQKVIIVTTSPSSTF EEEEEEEECCCCCCC	15.91	20068230
283	O-linked_Glycosylation	QKVIIVTTSPSSTFV EEEEEEECCCCCCCC	27.96	20068230
284	O-linked_Glycosylation	KVIIVTTSPSSTFVP EEEEEECCCCCCCCC	17.26	20068230
286	O-linked_Glycosylation	IIVTTSPSSTFVPNI EEEECCCCCCCCCCH	41.60	20068230
287	O-linked_Glycosylation	IVTTSPSSTFVPNIL EEECCCCCCCCCCHH	29.28	20068230
287	Phosphorylation	IVTTSPSSTFVPNIL EEECCCCCCCCCCHH	29.28	-
288	O-linked_Glycosylation	VTTSPSSTFVPNILS EECCCCCCCCCCHHH	32.75	20068230
292	Ubiquitination	PSSTFVPNILSKSHN CCCCCCCCHHHCCCC	42.40	22505724
295	O-linked_Glycosylation	TFVPNILSKSHNYAA CCCCCHHHCCCCEEE	28.45	20068230
296	Ubiquitination	FVPNILSKSHNYAAV CCCCHHHCCCCEEEE	52.90	29967540
297	Ubiquitination	VPNILSKSHNYAAVT CCCHHHCCCCEEEEE	17.37	29967540
300	Phosphorylation	ILSKSHNYAAVTKLV HHHCCCCEEEEECEE	7.18	-
309	Phosphorylation	AVTKLVPTSVIASTT EEECEECHHHCCCCC	28.31	29978859
310	Phosphorylation	VTKLVPTSVIASTTQ EECEECHHHCCCCCC	12.88	29978859
311	Ubiquitination	TKLVPTSVIASTTQK ECEECHHHCCCCCCC	4.69	29967540
314	Phosphorylation	VPTSVIASTTQKPPV ECHHHCCCCCCCCCE	22.36	29978859
315	Phosphorylation	PTSVIASTTQKPPVV CHHHCCCCCCCCCEE	24.99	29978859
365	O-linked_Glycosylation	STPSVVMSTVAQGVS CCCCHHHHHHCCCCC	14.23	OGP
380	Phosphorylation	TSAIKMASTRLPSPK HHHHHHHHCCCCCCH	15.57	26074081
381	Phosphorylation	SAIKMASTRLPSPKS HHHHHHHCCCCCCHH	27.04	26074081
385	Phosphorylation	MASTRLPSPKSLVSA HHHCCCCCCHHHCCC	49.94	25159151
387	Ubiquitination	STRLPSPKSLVSAPT HCCCCCCHHHCCCCH	61.84	-
388	Phosphorylation	TRLPSPKSLVSAPTQ CCCCCCHHHCCCCHH	37.07	28348404
401	Ubiquitination	TQILAQFPKQHQQSP HHHHHHCCHHHCCCH	24.26	-
402	Ubiquitination	QILAQFPKQHQQSPK HHHHHCCHHHCCCHH	62.80	-
402	Ubiquitination	QILAQFPKQHQQSPK HHHHHCCHHHCCCHH	62.80	29967540
403	Ubiquitination	ILAQFPKQHQQSPKQ HHHHCCHHHCCCHHH	39.60	29967540
407	Phosphorylation	FPKQHQQSPKQQLYQ CCHHHCCCHHHHHHH	27.74	26853621
417	Ubiquitination	QQLYQVQQQTQQQVA HHHHHHHHHHHHHHC	49.81	29967540
423	Ubiquitination	QQQTQQQVAQPSPVS HHHHHHHHCCCCCCC	4.67	-
424	Ubiquitination	QQTQQQVAQPSPVSH HHHHHHHCCCCCCCC	15.95	-
427	Phosphorylation	QQQVAQPSPVSHQQQ HHHHCCCCCCCCCCC	26.34	26425664
438	Phosphorylation	HQQQPQQSPLPPGIK CCCCCCCCCCCCCCC	24.13	26425664
451	Sumoylation	IKPTIQIKQESGVKI CCCEEEEEHHHCCEE	31.47	-
451	Sumoylation	IKPTIQIKQESGVKI CCCEEEEEHHHCCEE	31.47	-
466	Phosphorylation	ITQQVQPSKILPKPV EEEECCHHHCCCCCE	18.42	-
476	O-linked_Glycosylation	LPKPVTATLPTSSNS CCCCEEEECCCCCCC	24.73	20068230
501	O-linked_Glycosylation	IMTTKLVTTPTGTQA EEEEEEEECCCCCEE	37.18	32574038
501	O-linked_Glycosylation	IMTTKLVTTPTGTQA EEEEEEEECCCCCEE	37.18	20068230
501	Phosphorylation	IMTTKLVTTPTGTQA EEEEEEEECCCCCEE	37.18	-
502	O-linked_Glycosylation	MTTKLVTTPTGTQAT EEEEEEECCCCCEEE	16.04	20068230
502	Phosphorylation	MTTKLVTTPTGTQAT EEEEEEECCCCCEEE	16.04	30576142
504	O-linked_Glycosylation	TKLVTTPTGTQATYT EEEEECCCCCEEEEE	51.25	20068230
504	Phosphorylation	TKLVTTPTGTQATYT EEEEECCCCCEEEEE	51.25	27251275
506	O-linked_Glycosylation	LVTTPTGTQATYTRP EEECCCCCEEEEECC	19.94	32574038
506	O-linked_Glycosylation	LVTTPTGTQATYTRP EEECCCCCEEEEECC	19.94	20068230
506	Phosphorylation	LVTTPTGTQATYTRP EEECCCCCEEEEECC	19.94	27251275
509	O-linked_Glycosylation	TPTGTQATYTRPTVS CCCCCEEEEECCCCC	18.66	20068230
509	Phosphorylation	TPTGTQATYTRPTVS CCCCCEEEEECCCCC	18.66	30576142
511	O-linked_Glycosylation	TGTQATYTRPTVSPS CCCEEEEECCCCCCC	26.31	20068230
511	Phosphorylation	TGTQATYTRPTVSPS CCCEEEEECCCCCCC	26.31	30576142
514	O-linked_Glycosylation	QATYTRPTVSPSIGR EEEEECCCCCCCHHH	30.26	20068230
514	Phosphorylation	QATYTRPTVSPSIGR EEEEECCCCCCCHHH	30.26	20860994
516	O-linked_Glycosylation	TYTRPTVSPSIGRMA EEECCCCCCCHHHCC	18.53	20068230
516	Phosphorylation	TYTRPTVSPSIGRMA EEECCCCCCCHHHCC	18.53	20068231
518	O-linked_Glycosylation	TRPTVSPSIGRMAAT ECCCCCCCHHHCCCC	30.12	20068230
518	Phosphorylation	TRPTVSPSIGRMAAT ECCCCCCCHHHCCCC	30.12	20068231
525	Phosphorylation	SIGRMAATPGAATYV CHHHCCCCCCCCEEE	16.84	20068231
530	Phosphorylation	AATPGAATYVKTTSG CCCCCCCEEEEECCC	28.45	20068231
531	Phosphorylation	ATPGAATYVKTTSGS CCCCCCEEEEECCCC	8.67	20068231
534	O-linked_Glycosylation	GAATYVKTTSGSIIT CCCEEEEECCCCEEE	19.02	32574038
534	Phosphorylation	GAATYVKTTSGSIIT CCCEEEEECCCCEEE	19.02	20068231
535	O-linked_Glycosylation	AATYVKTTSGSIITV CCEEEEECCCCEEEE	25.93	32574038
535	Phosphorylation	AATYVKTTSGSIITV CCEEEEECCCCEEEE	25.93	20860994
536	O-linked_Glycosylation	ATYVKTTSGSIITVV CEEEEECCCCEEEEE	35.46	20068230
536	Phosphorylation	ATYVKTTSGSIITVV CEEEEECCCCEEEEE	35.46	20068231
538	O-linked_Glycosylation	YVKTTSGSIITVVPK EEEECCCCEEEEEEH	15.58	20068230
538	Phosphorylation	YVKTTSGSIITVVPK EEEECCCCEEEEEEH	15.58	20068231
541	O-linked_Glycosylation	TTSGSIITVVPKSLA ECCCCEEEEEEHHHH	17.49	20068230
541	Phosphorylation	TTSGSIITVVPKSLA ECCCCEEEEEEHHHH	17.49	20068231
546	O-linked_Glycosylation	IITVVPKSLATLGGK EEEEEEHHHHHCCCE	19.71	20068230
546	Phosphorylation	IITVVPKSLATLGGK EEEEEEHHHHHCCCE	19.71	23403867
547	Ubiquitination	ITVVPKSLATLGGKI EEEEEHHHHHCCCEE	5.43	22505724
549	Phosphorylation	VVPKSLATLGGKIIS EEEHHHHHCCCEEEE	31.09	23403867
553	Ubiquitination	SLATLGGKIISSNIV HHHHCCCEEEECCCC	34.76	29967540
554	Ubiquitination	LATLGGKIISSNIVS HHHCCCEEEECCCCC	4.11	29967540
556	O-linked_Glycosylation	TLGGKIISSNIVSGT HCCCEEEECCCCCCC	22.32	20068230
557	O-linked_Glycosylation	LGGKIISSNIVSGTT CCCEEEECCCCCCCC	21.84	32574038
557	O-linked_Glycosylation	LGGKIISSNIVSGTT CCCEEEECCCCCCCC	21.84	20068230
557	Phosphorylation	LGGKIISSNIVSGTT CCCEEEECCCCCCCC	21.84	30576142
561	O-linked_Glycosylation	IISSNIVSGTTTKIT EEECCCCCCCCEEEE	26.99	20068230
561	Phosphorylation	IISSNIVSGTTTKIT EEECCCCCCCCEEEE	26.99	21406692
561	Ubiquitination	IISSNIVSGTTTKIT EEECCCCCCCCEEEE	26.99	22505724
563	O-linked_Glycosylation	SSNIVSGTTTKITTI ECCCCCCCCEEEEEE	24.64	20068230
563	Phosphorylation	SSNIVSGTTTKITTI ECCCCCCCCEEEEEE	24.64	21406692
564	Phosphorylation	SNIVSGTTTKITTIP CCCCCCCCEEEEEEE	29.62	21406692
565	O-linked_Glycosylation	NIVSGTTTKITTIPM CCCCCCCEEEEEEEC	21.93	20068230
565	Phosphorylation	NIVSGTTTKITTIPM CCCCCCCEEEEEEEC	21.93	21406692
567	Ubiquitination	VSGTTTKITTIPMTS CCCCCEEEEEEECCC	3.74	-
568	Ubiquitination	SGTTTKITTIPMTSK CCCCEEEEEEECCCC	21.89	-
568	O-linked_Glycosylation	SGTTTKITTIPMTSK CCCCEEEEEEECCCC	21.89	20068230
568	Phosphorylation	SGTTTKITTIPMTSK CCCCEEEEEEECCCC	21.89	-
568	Ubiquitination	SGTTTKITTIPMTSK CCCCEEEEEEECCCC	21.89	29967540
569	Phosphorylation	GTTTKITTIPMTSKP CCCEEEEEEECCCCC	26.93	-
573	O-linked_Glycosylation	KITTIPMTSKPNVIV EEEEEECCCCCCEEE	28.39	20068230
574	O-linked_Glycosylation	ITTIPMTSKPNVIVV EEEEECCCCCCEEEE	39.60	20068230
575	Ubiquitination	TTIPMTSKPNVIVVQ EEEECCCCCCEEEEE	31.29	29967540
576	Ubiquitination	TIPMTSKPNVIVVQK EEECCCCCCEEEEEE	39.84	29967540
583	Ubiquitination	PNVIVVQKTTGKGTT CCEEEEEEECCCCCE	36.12	29967540
584	Ubiquitination	NVIVVQKTTGKGTTI CEEEEEEECCCCCEE	24.56	29967540
587	Ubiquitination	VVQKTTGKGTTIQGL EEEEECCCCCEEECC	51.49	29967540
588	Ubiquitination	VQKTTGKGTTIQGLP EEEECCCCCEEECCC	29.45	29967540
589	Ubiquitination	QKTTGKGTTIQGLPG EEECCCCCEEECCCC	24.98	-
589	Ubiquitination	QKTTGKGTTIQGLPG EEECCCCCEEECCCC	24.98	22505724
590	Ubiquitination	KTTGKGTTIQGLPGK EECCCCCEEECCCCC	21.70	-
590	Ubiquitination	KTTGKGTTIQGLPGK EECCCCCEEECCCCC	21.70	29967540
597	Ubiquitination	TIQGLPGKNVVTTLL EEECCCCCCEEEEEE	44.63	-
597	Ubiquitination	TIQGLPGKNVVTTLL EEECCCCCCEEEEEE	44.63	21906983
597 (in isoform 1)	Ubiquitination	-	44.63	21906983
597 (in isoform 2)	Ubiquitination	-	44.63	21906983
598	Ubiquitination	IQGLPGKNVVTTLLN EECCCCCCEEEEEEE	39.13	-
598	Ubiquitination	IQGLPGKNVVTTLLN EECCCCCCEEEEEEE	39.13	22505724
601	Ubiquitination	LPGKNVVTTLLNAGG CCCCCEEEEEEECCC	13.88	-
601	Phosphorylation	LPGKNVVTTLLNAGG CCCCCEEEEEEECCC	13.88	28851738
602	Ubiquitination	PGKNVVTTLLNAGGE CCCCEEEEEEECCCC	20.03	-
602	Phosphorylation	PGKNVVTTLLNAGGE CCCCEEEEEEECCCC	20.03	28851738
602	Ubiquitination	PGKNVVTTLLNAGGE CCCCEEEEEEECCCC	20.03	29967540
603	Ubiquitination	GKNVVTTLLNAGGEK CCCEEEEEEECCCCE	2.25	22505724
605	Ubiquitination	NVVTTLLNAGGEKTI CEEEEEEECCCCEEE	39.38	22505724
610	Ubiquitination	LLNAGGEKTIQTVPT EEECCCCEEEEECCC	54.95	29967540
611	Ubiquitination	LNAGGEKTIQTVPTG EECCCCEEEEECCCC	17.64	21906983
611	Ubiquitination	LNAGGEKTIQTVPTG EECCCCEEEEECCCC	17.64	22505724
612	Ubiquitination	NAGGEKTIQTVPTGA ECCCCEEEEECCCCC	4.84	-
612	Ubiquitination	NAGGEKTIQTVPTGA ECCCCEEEEECCCCC	4.84	22505724
619	Ubiquitination	IQTVPTGAKPAILTA EEECCCCCCCEEEEE	19.69	22505724
620	Acetylation	QTVPTGAKPAILTAT EECCCCCCCEEEEEC	36.01	23749302
620	Ubiquitination	QTVPTGAKPAILTAT EECCCCCCCEEEEEC	36.01	22817900
621	Ubiquitination	TVPTGAKPAILTATR ECCCCCCCEEEEECC	24.81	29967540
624	Ubiquitination	TGAKPAILTATRPIT CCCCCEEEEECCCEE	2.64	-
625	Ubiquitination	GAKPAILTATRPITK CCCCEEEEECCCEEE	21.62	-
625	Phosphorylation	GAKPAILTATRPITK CCCCEEEEECCCEEE	21.62	20860994
625	Ubiquitination	GAKPAILTATRPITK CCCCEEEEECCCEEE	21.62	29967540
634	Acetylation	TRPITKMIVTQPKGI CCCEEEEEEECCCCC	3.02	-
634	Ubiquitination	TRPITKMIVTQPKGI CCCEEEEEEECCCCC	3.02	-
635	Ubiquitination	RPITKMIVTQPKGIG CCEEEEEEECCCCCC	3.49	-
635	Ubiquitination	RPITKMIVTQPKGIG CCEEEEEEECCCCCC	3.49	29967540
636	Phosphorylation	PITKMIVTQPKGIGS CEEEEEEECCCCCCC	28.38	24532841
639	Sumoylation	KMIVTQPKGIGSTVQ EEEEECCCCCCCCCC	54.03	-
639	Sumoylation	KMIVTQPKGIGSTVQ EEEEECCCCCCCCCC	54.03	-
639	Ubiquitination	KMIVTQPKGIGSTVQ EEEEECCCCCCCCCC	54.03	22505724
640	Ubiquitination	MIVTQPKGIGSTVQP EEEECCCCCCCCCCC	35.85	22505724
643	Phosphorylation	TQPKGIGSTVQPAAK ECCCCCCCCCCCHHH	24.39	21712546
644	Phosphorylation	QPKGIGSTVQPAAKI CCCCCCCCCCCHHHC	20.25	24532841
650	Ubiquitination	STVQPAAKIIPTKIV CCCCCHHHCCCCEEE	43.18	29967540
651	Ubiquitination	TVQPAAKIIPTKIVY CCCCHHHCCCCEEEE	3.80	29967540
653	Ubiquitination	QPAAKIIPTKIVYGQ CCHHHCCCCEEEECC	30.98	-
653	Ubiquitination	QPAAKIIPTKIVYGQ CCHHHCCCCEEEECC	30.98	22505724
654	Ubiquitination	PAAKIIPTKIVYGQQ CHHHCCCCEEEECCC	24.01	-
654	Phosphorylation	PAAKIIPTKIVYGQQ CHHHCCCCEEEECCC	24.01	22210691
654	Ubiquitination	PAAKIIPTKIVYGQQ CHHHCCCCEEEECCC	24.01	22505724
655	Acetylation	AAKIIPTKIVYGQQG HHHCCCCEEEECCCC	25.48	25953088
655	Ubiquitination	AAKIIPTKIVYGQQG HHHCCCCEEEECCCC	25.48	22505724
656	Ubiquitination	AKIIPTKIVYGQQGK HHCCCCEEEECCCCC	2.95	22505724
658	Phosphorylation	IIPTKIVYGQQGKTQ CCCCEEEECCCCCEE	16.82	18083107
663	Ubiquitination	IVYGQQGKTQVLIKP EEECCCCCEEEEECC	31.29	29967540
664	Ubiquitination	VYGQQGKTQVLIKPK EECCCCCEEEEECCC	30.63	-
664	Ubiquitination	VYGQQGKTQVLIKPK EECCCCCEEEEECCC	30.63	29967540
665	Ubiquitination	YGQQGKTQVLIKPKP ECCCCCEEEEECCCC	31.35	-
665	Ubiquitination	YGQQGKTQVLIKPKP ECCCCCEEEEECCCC	31.35	29967540
669	Ubiquitination	GKTQVLIKPKPVTFQ CCEEEEECCCCEEEE	42.71	-
669	Ubiquitination	GKTQVLIKPKPVTFQ CCEEEEECCCCEEEE	42.71	22505724
670	Ubiquitination	KTQVLIKPKPVTFQA CEEEEECCCCEEEEE	38.91	-
670	Ubiquitination	KTQVLIKPKPVTFQA CEEEEECCCCEEEEE	38.91	22505724
671	Acetylation	TQVLIKPKPVTFQAT EEEEECCCCEEEEEE	47.30	26051181
678	Ubiquitination	KPVTFQATVVSEQTR CCEEEEEEECCHHHH	15.62	29967540
683	Ubiquitination	QATVVSEQTRQLVTE EEEECCHHHHHHHHH	34.18	-
684	Ubiquitination	ATVVSEQTRQLVTET EEECCHHHHHHHHHH	19.14	-
684	Ubiquitination	ATVVSEQTRQLVTET EEECCHHHHHHHHHH	19.14	29967540
705	Phosphorylation	VAEAGNSSIQEGKEE HHHHCCCCHHCCCCC	32.08	21815630
710	Sumoylation	NSSIQEGKEEPQNYT CCCHHCCCCCCCCCC	59.14	-
710	Ubiquitination	NSSIQEGKEEPQNYT CCCHHCCCCCCCCCC	59.14	21906983
710 (in isoform 1)	Ubiquitination	-	59.14	21906983
710 (in isoform 2)	Ubiquitination	-	59.14	21906983
725	Ubiquitination	DSSSSSTESSQSSQD CCCCCCCCCCCCCCC	50.79	-
756	Phosphorylation	EHEIAMETSPTIIYQ HHHHHHCCCCEEEEE	27.24	30576142
762	Phosphorylation	ETSPTIIYQDVSSES CCCCEEEEECCCCCC	8.53	-
766	Phosphorylation	TIIYQDVSSESQSAT EEEEECCCCCCCCHH	36.36	30576142
767	Phosphorylation	IIYQDVSSESQSATS EEEECCCCCCCCHHH	40.91	30576142
779	Ubiquitination	ATSTIKALLELQQTT HHHHHHHHHHHHHHH	3.03	21987572
788	Ubiquitination	ELQQTTVKEKLESKP HHHHHHHHHHHHCCC	47.22	29967540
789	Ubiquitination	LQQTTVKEKLESKPR HHHHHHHHHHHCCCC	59.54	29967540
793	Phosphorylation	TVKEKLESKPRQPTI HHHHHHHCCCCCCCC	59.40	-
796	Ubiquitination	EKLESKPRQPTIDLS HHHHCCCCCCCCCHH	59.87	22817900
799	Phosphorylation	ESKPRQPTIDLSQMA HCCCCCCCCCHHHCC	20.84	27251275
803	Ubiquitination	RQPTIDLSQMAVPIQ CCCCCCHHHCCEEEC	17.73	29967540
805	Ubiquitination	PTIDLSQMAVPIQMT CCCCHHHCCEEECCC	3.50	-
815	Ubiquitination	PIQMTQEKRHSPESP EECCCCCCCCCCCCC	45.66	21906983
815 (in isoform 1)	Ubiquitination	-	45.66	21906983
815 (in isoform 2)	Ubiquitination	-	45.66	21906983
818	Phosphorylation	MTQEKRHSPESPSIA CCCCCCCCCCCCCEE	34.10	30108239
821	Phosphorylation	EKRHSPESPSIAVVE CCCCCCCCCCEEEEC	27.60	30108239
823	Phosphorylation	RHSPESPSIAVVESE CCCCCCCCEEEECCH	32.24	20363803
829	Phosphorylation	PSIAVVESELVAEYI CCEEEECCHHHEEEC	25.31	27732954
830	Ubiquitination	SIAVVESELVAEYIT CEEEECCHHHEEECC	33.48	-
833 (in isoform 4)	Phosphorylation	-	19.25	24719451
836 (in isoform 4)	Phosphorylation	-	2.64	24719451
838 (in isoform 4)	Phosphorylation	-	17.57	29523821
844	Ubiquitination	TTERTDEGTEVAFPL CCCCCCCCCEEEEEE	29.95	21987572
859	Ubiquitination	LVSHRSQPQQPSQPQ EEECCCCCCCCCCHH	35.70	21906983
861	Ubiquitination	SHRSQPQQPSQPQRT ECCCCCCCCCCHHHH	46.42	22817900
862	Ubiquitination	HRSQPQQPSQPQRTL CCCCCCCCCCHHHHH	29.68	21906983
868	O-linked_Glycosylation	QPSQPQRTLLQHVAQ CCCCHHHHHHHHHHH	26.94	20068230
876	Ubiquitination	LLQHVAQSQTATQTS HHHHHHHCCCCCCEE	21.54	-
876	O-linked_Glycosylation	LLQHVAQSQTATQTS HHHHHHHCCCCCCEE	21.54	20068230
876	Phosphorylation	LLQHVAQSQTATQTS HHHHHHHCCCCCCEE	21.54	-
880	O-linked_Glycosylation	VAQSQTATQTSVVVK HHHCCCCCCEEEEEE	35.45	20068230
882	O-linked_Glycosylation	QSQTATQTSVVVKSI HCCCCCCEEEEEEEC	21.09	20068230
883	O-linked_Glycosylation	SQTATQTSVVVKSIP CCCCCCEEEEEEECC	11.78	20068230
888	Phosphorylation	QTSVVVKSIPASSPG CEEEEEEECCCCCCC	23.38	24732914
892	Phosphorylation	VVKSIPASSPGAITH EEEECCCCCCCHHHH	31.54	24732914
893	Phosphorylation	VKSIPASSPGAITHI EEECCCCCCCHHHHH	29.47	25849741
898	Phosphorylation	ASSPGAITHIMQQAL CCCCCHHHHHHHHHH	12.57	24732914
900	Ubiquitination	SPGAITHIMQQALSS CCCHHHHHHHHHHHC	1.67	21987572
906	Phosphorylation	HIMQQALSSHTAFTK HHHHHHHHCCCCHHH	24.08	24732914
907	Phosphorylation	IMQQALSSHTAFTKH HHHHHHHCCCCHHHC	26.21	24732914
909	Phosphorylation	QQALSSHTAFTKHSE HHHHHCCCCHHHCHH	25.97	24732914
912	Ubiquitination	LSSHTAFTKHSEELG HHCCCCHHHCHHHHC	25.94	-
912	Phosphorylation	LSSHTAFTKHSEELG HHCCCCHHHCHHHHC	25.94	24732914
916	Ubiquitination	TAFTKHSEELGTEEG CCHHHCHHHHCCCCC	57.89	21987572
917	Ubiquitination	AFTKHSEELGTEEGE CHHHCHHHHCCCCCE	56.36	22817900
926	Ubiquitination	GTEEGEVEEMDTLDP CCCCCEEEECCCCCC	43.21	21987572
930	Ubiquitination	GEVEEMDTLDPQTGL CEEEECCCCCCCCCH	31.58	21987572
933	Ubiquitination	EEMDTLDPQTGLFYR EECCCCCCCCCHHHH	36.42	22817900
937	Ubiquitination	TLDPQTGLFYRSALT CCCCCCCHHHHHHHH	3.76	-
937	Ubiquitination	TLDPQTGLFYRSALT CCCCCCCHHHHHHHH	3.76	21987572
943	Ubiquitination	GLFYRSALTQSQSAK CHHHHHHHHHCHHHH	4.76	22817900
946	Phosphorylation	YRSALTQSQSAKQQK HHHHHHHCHHHHHHC	22.37	24275569
947	Ubiquitination	RSALTQSQSAKQQKL HHHHHHCHHHHHHCC	37.28	22817900
950	Ubiquitination	LTQSQSAKQQKLSQP HHHCHHHHHHCCCCC	59.51	21906983
950 (in isoform 1)	Ubiquitination	-	59.51	21906983
950 (in isoform 2)	Ubiquitination	-	59.51	21906983
951	Ubiquitination	TQSQSAKQQKLSQPP HHCHHHHHHCCCCCC	45.41	21987572
953	Ubiquitination	SQSAKQQKLSQPPLE CHHHHHHCCCCCCHH	47.84	2190698
953 (in isoform 1)	Ubiquitination	-	47.84	21906983
953 (in isoform 2)	Ubiquitination	-	47.84	21906983
954	Ubiquitination	QSAKQQKLSQPPLEQ HHHHHHCCCCCCHHH	5.10	22817900
965	Ubiquitination	PLEQTQLQVKTLQCF CHHHHHHHHHHHHHH	25.50	-
965	Ubiquitination	PLEQTQLQVKTLQCF CHHHHHHHHHHHHHH	25.50	21987572
967	Ubiquitination	EQTQLQVKTLQCFQT HHHHHHHHHHHHHCC	30.47	22817900
968	Ubiquitination	QTQLQVKTLQCFQTK HHHHHHHHHHHHCCC	24.17	-
968	Ubiquitination	QTQLQVKTLQCFQTK HHHHHHHHHHHHCCC	24.17	22817900
975	Acetylation	TLQCFQTKQKQTIHL HHHHHCCCCCCEEEE	44.72	26051181
975	Ubiquitination	TLQCFQTKQKQTIHL HHHHHCCCCCCEEEE	44.72	29967540
976	Ubiquitination	LQCFQTKQKQTIHLQ HHHHCCCCCCEEEEE	46.61	29967540
977	Ubiquitination	QCFQTKQKQTIHLQA HHHCCCCCCEEEEEH	51.47	29967540
978	Ubiquitination	CFQTKQKQTIHLQAD HHCCCCCCEEEEEHH	43.10	29967540
980	Ubiquitination	QTKQKQTIHLQADQL CCCCCCEEEEEHHHH	2.57	21987572
981	Ubiquitination	TKQKQTIHLQADQLQ CCCCCEEEEEHHHHH	18.44	21987572
982	Ubiquitination	KQKQTIHLQADQLQH CCCCEEEEEHHHHHH	3.87	-
982	Ubiquitination	KQKQTIHLQADQLQH CCCCEEEEEHHHHHH	3.87	22817900
984	Ubiquitination	KQTIHLQADQLQHKL CCEEEEEHHHHHHHC	16.93	22817900
990	Ubiquitination	QADQLQHKLPQMPQL EHHHHHHHCCCCCCC	49.23	29967540
991	Ubiquitination	ADQLQHKLPQMPQLS HHHHHHHCCCCCCCC	3.14	29967540
992	Ubiquitination	DQLQHKLPQMPQLSI HHHHHHCCCCCCCCH	32.97	29967540
997	Ubiquitination	KLPQMPQLSIRHQKL HCCCCCCCCHHHCCC	3.66	22817900
998	Ubiquitination	LPQMPQLSIRHQKLT CCCCCCCCHHHCCCC	16.60	22817900
1003	Ubiquitination	QLSIRHQKLTPLQQE CCCHHHCCCCHHHHH	48.48	29967540
1004	Ubiquitination	LSIRHQKLTPLQQEQ CCHHHCCCCHHHHHH	4.85	29967540
1005	Ubiquitination	SIRHQKLTPLQQEQA CHHHCCCCHHHHHHC	29.05	29967540
1015	Sumoylation	QQEQAQPKPDVQHTQ HHHHCCCCCCCCCCC	41.59	-
1015	Sumoylation	QQEQAQPKPDVQHTQ HHHHCCCCCCCCCCC	41.59	-
1015	Ubiquitination	QQEQAQPKPDVQHTQ HHHHCCCCCCCCCCC	41.59	29967540
1016	Ubiquitination	QEQAQPKPDVQHTQH HHHCCCCCCCCCCCC	54.40	29967540
1018	Ubiquitination	QAQPKPDVQHTQHPM HCCCCCCCCCCCCCC	6.44	-
1018	Ubiquitination	QAQPKPDVQHTQHPM HCCCCCCCCCCCCCC	6.44	29967540
1028	Ubiquitination	TQHPMVAKDRQLPTL CCCCCCCCCCCCCCC	41.87	29967540
1029	Ubiquitination	QHPMVAKDRQLPTLM CCCCCCCCCCCCCCC	33.54	29967540
1030	Ubiquitination	HPMVAKDRQLPTLMA CCCCCCCCCCCCCCC	38.95	29967540
1034	Phosphorylation	AKDRQLPTLMAQPPQ CCCCCCCCCCCCCCC	37.44	24043423
1042	Phosphorylation	LMAQPPQTVVQVLAV CCCCCCCEEEEEEEE	28.55	24043423
1043	Ubiquitination	MAQPPQTVVQVLAVK CCCCCCEEEEEEEEE	2.09	-
1043	Ubiquitination	MAQPPQTVVQVLAVK CCCCCCEEEEEEEEE	2.09	29967540
1051	Phosphorylation	VQVLAVKTTQQLPKL EEEEEEEEHHHCCHH	24.20	21406692
1052	Ubiquitination	QVLAVKTTQQLPKLQ EEEEEEEHHHCCHHH	14.48	-
1052	Phosphorylation	QVLAVKTTQQLPKLQ EEEEEEEHHHCCHHH	14.48	21406692
1066	Ubiquitination	QQAPNQPKIYVQPQT HCCCCCCCEEECCCC	36.58	29967540
1067	Ubiquitination	QAPNQPKIYVQPQTP CCCCCCCEEECCCCC	5.32	29967540
1073	Phosphorylation	KIYVQPQTPQSQMSL CEEECCCCCCCCCCC	29.94	25159151
1076	Phosphorylation	VQPQTPQSQMSLPAS ECCCCCCCCCCCCCC	29.11	28555341
1079	Phosphorylation	QTPQSQMSLPASSEK CCCCCCCCCCCCCCC	24.46	-
1081	Ubiquitination	PQSQMSLPASSEKQT CCCCCCCCCCCCCCC	23.84	29967540
1083	Phosphorylation	SQMSLPASSEKQTAS CCCCCCCCCCCCCHH	36.77	28555341
1084	Phosphorylation	QMSLPASSEKQTASQ CCCCCCCCCCCCHHH	51.42	28555341
1088	Phosphorylation	PASSEKQTASQVEQP CCCCCCCCHHHCCCC	39.07	30622161
1090	O-linked_Glycosylation	SSEKQTASQVEQPII CCCCCCHHHCCCCEE	37.84	20068230
1090	Phosphorylation	SSEKQTASQVEQPII CCCCCCHHHCCCCEE	37.84	30622161
1098	O-linked_Glycosylation	QVEQPIITQGSSVTK HCCCCEECCCCCEEE	27.83	20068230
1098	Phosphorylation	QVEQPIITQGSSVTK HCCCCEECCCCCEEE	27.83	30622161
1101	Phosphorylation	QPIITQGSSVTKITF CCEECCCCCEEEEEE	16.30	25627689
1102	Phosphorylation	PIITQGSSVTKITFE CEECCCCCEEEEEEC	40.40	25627689
1104	Phosphorylation	ITQGSSVTKITFEGR ECCCCCEEEEEECCC	20.76	25627689
1115	O-linked_Glycosylation	FEGRQPPTVTKITGG ECCCCCCCEEEECCC	47.71	20068230
1120	O-linked_Glycosylation	PPTVTKITGGSSVPK CCCEEEECCCCCCCC	36.73	32574038
1120	O-linked_Glycosylation	PPTVTKITGGSSVPK CCCEEEECCCCCCCC	36.73	20068230
1120	Phosphorylation	PPTVTKITGGSSVPK CCCEEEECCCCCCCC	36.73	25867546
1123	O-linked_Glycosylation	VTKITGGSSVPKLTS EEEECCCCCCCCCCC	29.52	20068230
1123	Phosphorylation	VTKITGGSSVPKLTS EEEECCCCCCCCCCC	29.52	25867546
1124	O-linked_Glycosylation	TKITGGSSVPKLTSP EEECCCCCCCCCCCC	45.79	20068230
1124	Phosphorylation	TKITGGSSVPKLTSP EEECCCCCCCCCCCC	45.79	25867546
1129	Phosphorylation	GSSVPKLTSPVTSIS CCCCCCCCCCCCCCC	36.79	30266825
1130	Phosphorylation	SSVPKLTSPVTSISP CCCCCCCCCCCCCCC	28.01	30266825
1133	Phosphorylation	PKLTSPVTSISPIQA CCCCCCCCCCCCCCC	24.59	30266825
1134	O-linked_Glycosylation	KLTSPVTSISPIQAS CCCCCCCCCCCCCCC	22.69	20068230
1134	Phosphorylation	KLTSPVTSISPIQAS CCCCCCCCCCCCCCC	22.69	30266825
1136	Phosphorylation	TSPVTSISPIQASEK CCCCCCCCCCCCCCC	18.73	29255136
1141	Phosphorylation	SISPIQASEKTAVSD CCCCCCCCCCHHHHH	24.21	30266825
1143	Ubiquitination	SPIQASEKTAVSDIL CCCCCCCCHHHHHHH	39.01	-
1158	Ubiquitination	KMSLMEAQIDTNVEH HHHHHHCCCCCCCHH	22.30	-
1200	Phosphorylation	VVAGMANSTPQQQKC EEECCCCCCHHHHHH	31.74	25159151
1201	Phosphorylation	VAGMANSTPQQQKCR EECCCCCCHHHHHHH	25.56	25159151
1210	Phosphorylation	QQQKCRESCSSPSTV HHHHHHHHCCCCCCC	10.43	21712546
1212	Phosphorylation	QKCRESCSSPSTVGS HHHHHHCCCCCCCCC	55.34	30266825
1213	Phosphorylation	KCRESCSSPSTVGSS HHHHHCCCCCCCCCC	27.48	23401153
1215	Phosphorylation	RESCSSPSTVGSSLT HHHCCCCCCCCCCCC	37.36	30266825
1216	Phosphorylation	ESCSSPSTVGSSLTT HHCCCCCCCCCCCCC	32.07	27794612
1219	Phosphorylation	SSPSTVGSSLTTRKI CCCCCCCCCCCCCCC	20.17	28450419
1220	Phosphorylation	SPSTVGSSLTTRKID CCCCCCCCCCCCCCC	24.65	30108239
1222	Phosphorylation	STVGSSLTTRKIDPP CCCCCCCCCCCCCCC	26.88	20068231
1223	Phosphorylation	TVGSSLTTRKIDPPA CCCCCCCCCCCCCCC	34.95	20068231
1246	Acetylation	RIQNVGQKKAEESPA EEEECCCCCCCCCCH	48.28	25953088

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
207	T	Phosphorylation	Kinase	AKT3	Q9Y243	PSP
207	T	Phosphorylation	Kinase	PKACA	P17612	PSP
209	S	Phosphorylation	Kinase	AKT1	P31749	PSP
209	S	Phosphorylation	Kinase	AKT3	Q9Y243	PSP

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EMSY_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EMSY_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BRCA2_HUMAN	BRCA2	physical	14651845
CBX1_HUMAN	CBX1	physical	14651845
ZMY11_HUMAN	ZMYND11	physical	14651845
CBX1_HUMAN	CBX1	physical	15947784
ASH2L_HUMAN	ASH2L	physical	19131338
CCAR2_HUMAN	CCAR2	physical	19131338
RBBP5_HUMAN	RBBP5	physical	19131338
ZN281_HUMAN	ZNF281	physical	26841866
MO4L1_HUMAN	MORF4L1	physical	26841866
SIN3B_HUMAN	SIN3B	physical	26841866
KDM5A_HUMAN	KDM5A	physical	26841866
ZN131_HUMAN	ZNF131	physical	26841866
HDAC1_HUMAN	HDAC1	physical	26841866
MO4L2_HUMAN	MORF4L2	physical	26841866
RBBP7_HUMAN	RBBP7	physical	26841866
EMSY_HUMAN	C11orf30	physical	26841866
QSER1_HUMAN	QSER1	physical	26841866
CHD9_HUMAN	CHD9	physical	26841866
GATD1_HUMAN	GATAD1	physical	26841866
HDAC2_HUMAN	HDAC2	physical	26841866
PHF12_HUMAN	PHF12	physical	26841866
AKAP8_HUMAN	AKAP8	physical	26841866
SPF27_HUMAN	BCAS2	physical	26841866
K1C18_HUMAN	KRT18	physical	26841866
RU2A_HUMAN	SNRPA1	physical	26841866
SON_HUMAN	SON	physical	26841866
NU214_HUMAN	NUP214	physical	26841866
HNRPM_HUMAN	HNRNPM	physical	26841866
NUP98_HUMAN	NUP98	physical	26841866
PHC3_HUMAN	PHC3	physical	26841866
NUP88_HUMAN	NUP88	physical	26841866

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-207 AND SER-209, ANDMASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209; SER-213; SER-238;SER-1130 AND SER-1136, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209; SER-1130 ANDSER-1136, AND MASS SPECTROMETRY.
PubMed: 18669648

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209; SER-238 ANDSER-1136, AND MASS SPECTROMETRY.
PubMed: 15302935

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-262; THR-273 ANDTHR-274, AND MASS SPECTROMETRY.
PubMed: 17924679