dbPTM

CE170_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CE170_MOUSE
UniProt AC	Q6A065
Protein Name	Centrosomal protein of 170 kDa
Gene Name	Cep170
Organism	Mus musculus (Mouse).
Sequence Length	1588
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, spindle . Associated with the mature mother centriole. Associated with spindle microtubules during mitosis (By similarity). Localizes to the dist
Protein Description	Plays a role in microtubule organization. Required for centriole subdistal appendage assembly..
Protein Sequence	MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVEAAAEVQPRATEALKSEEKPMDVSAMPRGTPLYGQPSWWGDAEEDEQRAFKANGKPEGKSQEAGASGCSTEAKHVEGQSAAASEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHTAGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKASPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKAQSTEKHQEQAATSSTHHRGGHGVPHGKLLKQKSEEPSVSLPFLQTALLRSSGSLGHRPSQEMDVMLKNQATSASSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLIKDWALNSAAVVMEERKPLSTPGFHNSEEAISSSGSKRWVSQWASLAANHTRHDPEERLMELSATVENETDTGDAGVSLRSTSCTTSLASQGERKRRTLPQLPNEEKLLESSRAKVVPQRSEIGEKQDTELQEKEAQVYQSEKHDADRGLSKMSRAVNGESPKTGGDGKALLHSGSSSSKEKSETEKETSLVKQTLAKMQQQEQKEQAQWTPTKFPSKNALGHIDKCREESSKQESQLLEKVSGHSTSKGDRVIQNESKRRKAEEIPKCQASKGDKKESSKSLVRQGSFTIDKPSSNIPIELIPHINKQNSSVPTALALTSASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDVTKSGSREKIEKKAKSRSADIGARADGRKFVQSSGRIRQPSIDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRTPLTSADEHNIHSKLEGGKATKSKTSPVASGSTSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASARTAEAVIRSGARLVPSDKLSPRTRANSISRLSDSKVKSMSSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSVDSRPQPAEHPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIENKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHSSPSQTPALCPPETRALHPAAAGVAAAASTEFENAESEADFSIHFNRFNPDGEEEDVTVHE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLTSWFLV ------CCCCCEEEE	52.22	20415495
3 (in isoform 3)	Phosphorylation	-	7.19	25521595
4	Phosphorylation	----MSLTSWFLVSS ----CCCCCEEEECC	32.95	20415495
5	Phosphorylation	---MSLTSWFLVSSG ---CCCCCEEEECCC	22.56	20415495
75 (in isoform 3)	Phosphorylation	-	53.86	25338131
78	Phosphorylation	VRIPEQTYITLKLED EECCCCCEEEEEEHH	7.51	22871156
122	Phosphorylation	FTIQLQLSQKSSESE EEEEEECCCCCCCCC	23.70	22324799
125	Phosphorylation	QLQLSQKSSESELPK EEECCCCCCCCCCCC	31.53	29899451
126	Phosphorylation	LQLSQKSSESELPKS EECCCCCCCCCCCCC	52.78	25521595
128	Phosphorylation	LSQKSSESELPKSAS CCCCCCCCCCCCCCC	46.51	-
133	Phosphorylation	SESELPKSASAKGTD CCCCCCCCCCCCCCC	26.05	-
135	Phosphorylation	SELPKSASAKGTDSK CCCCCCCCCCCCCHH	37.29	29514104
139	Phosphorylation	KSASAKGTDSKVEAA CCCCCCCCCHHHHHH	36.07	-
141	Phosphorylation	ASAKGTDSKVEAAAE CCCCCCCHHHHHHHH	38.14	-
159	Phosphorylation	RATEALKSEEKPMDV HHHHHHHCCCCCCCC	52.41	22067460
173	Phosphorylation	VSAMPRGTPLYGQPS CCCCCCCCCCCCCCC	16.05	25619855
203	Phosphorylation	NGKPEGKSQEAGASG CCCCCCCCCCCCCCC	44.07	27841257
209	Phosphorylation	KSQEAGASGCSTEAK CCCCCCCCCCCCCHH	39.14	26745281
212	Phosphorylation	EAGASGCSTEAKHVE CCCCCCCCCCHHCCC	32.57	26745281
213	Phosphorylation	AGASGCSTEAKHVEG CCCCCCCCCHHCCCC	44.00	26745281
222	Phosphorylation	AKHVEGQSAAASEEA HHCCCCCCCCCCHHH	30.63	27149854
226	Phosphorylation	EGQSAAASEEALFPF CCCCCCCCHHHHHCC	31.10	26824392
238	Phosphorylation	FPFCREPSYFEIPTK HCCCCCCCCCCCCCH	37.39	25521595
239	Phosphorylation	PFCREPSYFEIPTKE CCCCCCCCCCCCCHH	18.88	22817900
251	Phosphorylation	TKEFQQPSQIAESTI CHHCCCHHHHHHCCC	29.85	29514104
256	Phosphorylation	QPSQIAESTIHEIPT CHHHHHHCCCEECCC	24.52	29514104
280	Phosphorylation	GAGHASFTIEFDDST CCCEEEEEEEECCCC	19.66	25619855
312	Phosphorylation	RHKSKKASPGTQDLP HHHCCCCCCCCCCCC	32.51	25521595
315	Phosphorylation	SKKASPGTQDLPGIQ CCCCCCCCCCCCCCC	23.46	25521595
349	Phosphorylation	PQMVWERTEEDSKSI CCCCEECCHHHHHHH	32.01	25619855
353	Phosphorylation	WERTEEDSKSIKSDV EECCHHHHHHHHCCC	31.42	18388127
355	Phosphorylation	RTEEDSKSIKSDVPV CCHHHHHHHHCCCCH	38.92	18388127
358	Phosphorylation	EDSKSIKSDVPVYLK HHHHHHHCCCCHHHH	42.02	25521595
363	Phosphorylation	IKSDVPVYLKRLKGN HHCCCCHHHHHHCCC	10.63	25619855
376	Phosphorylation	GNKHDDGTQSDSENA CCCCCCCCCCHHHCC	31.71	27087446
378	Phosphorylation	KHDDGTQSDSENAGA CCCCCCCCHHHCCCH	42.83	25521595
380	Phosphorylation	DDGTQSDSENAGAHR CCCCCCHHHCCCHHH	37.69	30387612
394	Phosphorylation	RRCSKRATLEEHLRR HHHHHHHHHHHHHHH	38.44	29899451
404	Phosphorylation	EHLRRHHSEQKKKAQ HHHHHHHHHHHHHHH	35.28	-
412	Phosphorylation	EQKKKAQSTEKHQEQ HHHHHHHHHHHHHHH	43.31	22067460
428	Methylation	ATSSTHHRGGHGVPH HHHCCCCCCCCCCCC	45.22	-
443	Phosphorylation	GKLLKQKSEEPSVSL HHHCCCCCCCCCCCH	44.70	27087446
447	Phosphorylation	KQKSEEPSVSLPFLQ CCCCCCCCCCHHHHH	27.84	25177544
449	Phosphorylation	KSEEPSVSLPFLQTA CCCCCCCCHHHHHHH	34.36	26745281
455	Phosphorylation	VSLPFLQTALLRSSG CCHHHHHHHHHHCCC	22.78	26643407
460	Phosphorylation	LQTALLRSSGSLGHR HHHHHHHCCCCCCCC	38.73	30635358
461	Phosphorylation	QTALLRSSGSLGHRP HHHHHHCCCCCCCCC	26.43	30635358
463	Phosphorylation	ALLRSSGSLGHRPSQ HHHHCCCCCCCCCCH	32.88	26824392
469	Phosphorylation	GSLGHRPSQEMDVML CCCCCCCCHHHHHHH	38.44	26160508
481	Phosphorylation	VMLKNQATSASSEKD HHHCCCCCCCCCCCC	18.30	26160508
482	Phosphorylation	MLKNQATSASSEKDN HHCCCCCCCCCCCCC	29.21	23429704
484	Phosphorylation	KNQATSASSEKDNDD CCCCCCCCCCCCCCC	38.50	23429704
485	Phosphorylation	NQATSASSEKDNDDD CCCCCCCCCCCCCCC	48.67	23429704
494	Phosphorylation	KDNDDDQSDKGTYTI CCCCCCCCCCCEEEE	48.56	25521595
498	Phosphorylation	DDQSDKGTYTIELEN CCCCCCCEEEEEEEC	24.19	24925903
499	Phosphorylation	DQSDKGTYTIELENP CCCCCCEEEEEEECC	17.87	24925903
500	Phosphorylation	QSDKGTYTIELENPN CCCCCEEEEEEECCC	14.07	25521595
508	Phosphorylation	IELENPNSEEVEARK EEEECCCHHHHHHHH	36.07	30635358
529	Phosphorylation	GVDDNQDYNRPIINE CCCCCCCCCCCCCCH	11.87	29514104
561	Phosphorylation	MEERKPLSTPGFHNS HHCCCCCCCCCCCCC	40.87	28066266
562	Phosphorylation	EERKPLSTPGFHNSE HCCCCCCCCCCCCCH	34.80	28066266
568	Phosphorylation	STPGFHNSEEAISSS CCCCCCCCHHHHHCC	28.39	28066266
573	Phosphorylation	HNSEEAISSSGSKRW CCCHHHHHCCCCHHH	26.04	28066266
574	Phosphorylation	NSEEAISSSGSKRWV CCHHHHHCCCCHHHH	32.38	28066266
575	Phosphorylation	SEEAISSSGSKRWVS CHHHHHCCCCHHHHH	40.05	28066266
577	Phosphorylation	EAISSSGSKRWVSQW HHHHCCCCHHHHHHH	22.46	28066266
586	Phosphorylation	RWVSQWASLAANHTR HHHHHHHHHHHHCCC	18.64	29899451
622	Phosphorylation	DAGVSLRSTSCTTSL CCCEEEEECCCCCCC	29.93	29899451
623	Phosphorylation	AGVSLRSTSCTTSLA CCEEEEECCCCCCCH	22.76	30635358
624	Phosphorylation	GVSLRSTSCTTSLAS CEEEEECCCCCCCHH	15.65	30635358
626	Phosphorylation	SLRSTSCTTSLASQG EEEECCCCCCCHHCC	21.13	30635358
627	Phosphorylation	LRSTSCTTSLASQGE EEECCCCCCCHHCCH	26.52	30635358
628	Phosphorylation	RSTSCTTSLASQGER EECCCCCCCHHCCHH	12.09	30635358
631	Phosphorylation	SCTTSLASQGERKRR CCCCCCHHCCHHHCC	43.97	22067460
639	Phosphorylation	QGERKRRTLPQLPNE CCHHHCCCCCCCCCH	46.99	28066266
662	Phosphorylation	AKVVPQRSEIGEKQD CEECCCHHHHCCCCC	28.46	27180971
680	Phosphorylation	QEKEAQVYQSEKHDA HHHHHHHHHHHHCHH	8.34	29514104
702	Phosphorylation	SRAVNGESPKTGGDG HHHHCCCCCCCCCCC	32.85	27841257
715	Phosphorylation	DGKALLHSGSSSSKE CCCEEEECCCCCCCC	40.10	28066266
717	Phosphorylation	KALLHSGSSSSKEKS CEEEECCCCCCCCCC	30.02	28066266
718	Phosphorylation	ALLHSGSSSSKEKSE EEEECCCCCCCCCCH	42.00	28066266
719	Phosphorylation	LLHSGSSSSKEKSET EEECCCCCCCCCCHH	47.31	28066266
720	Phosphorylation	LHSGSSSSKEKSETE EECCCCCCCCCCHHH	46.94	29899451
723	Ubiquitination	GSSSSKEKSETEKET CCCCCCCCCHHHHHH	58.28	-
731	Phosphorylation	SETEKETSLVKQTLA CHHHHHHHHHHHHHH	32.05	22067460
752	Phosphorylation	QKEQAQWTPTKFPSK HHHHHCCCCCCCCCC	14.70	28066266
754	Phosphorylation	EQAQWTPTKFPSKNA HHHCCCCCCCCCCHH	37.63	28066266
799	Phosphorylation	DRVIQNESKRRKAEE HHHCCCHHHHHCHHH	38.73	29514104
823	Phosphorylation	DKKESSKSLVRQGSF CCCCCCHHHHHCCCE	33.76	26643407
829	Phosphorylation	KSLVRQGSFTIDKPS HHHHHCCCEEECCCC	15.75	24925903
831	Phosphorylation	LVRQGSFTIDKPSSN HHHCCCEEECCCCCC	29.93	24925903
836	Phosphorylation	SFTIDKPSSNIPIEL CEEECCCCCCCCHHH	41.58	24925903
837	Phosphorylation	FTIDKPSSNIPIELI EEECCCCCCCCHHHC	47.51	24925903
852	Phosphorylation	PHINKQNSSVPTALA CCCCCCCCCCCHHHH	30.16	29899451
853	Phosphorylation	HINKQNSSVPTALAL CCCCCCCCCCHHHHH	39.40	22067460
862	Phosphorylation	PTALALTSASRLRER CHHHHHHHHHHHHHC	25.71	22067460
870	Phosphorylation	ASRLRERSDSLDTDS HHHHHHCCCCCCCCC	27.14	27087446
872	Phosphorylation	RLRERSDSLDTDSSM HHHHCCCCCCCCCCC	29.41	27087446
875	Phosphorylation	ERSDSLDTDSSMDTT HCCCCCCCCCCCCEE	42.97	21082442
877	Phosphorylation	SDSLDTDSSMDTTLI CCCCCCCCCCCEEEE	29.65	25619855
878	Phosphorylation	DSLDTDSSMDTTLIL CCCCCCCCCCEEEEE	24.40	25619855
881	Phosphorylation	DTDSSMDTTLILKDT CCCCCCCEEEEECCH	18.17	25619855
882	Phosphorylation	TDSSMDTTLILKDTE CCCCCCEEEEECCHH	13.92	25619855
906	Phosphorylation	LREDNNKTDEGPDTP HHHCCCCCCCCCCCC	41.21	25619855
912	Phosphorylation	KTDEGPDTPSYNRDN CCCCCCCCCCCCCCC	19.78	25619855
914	Phosphorylation	DEGPDTPSYNRDNSI CCCCCCCCCCCCCCC	36.81	25619855
915	Phosphorylation	EGPDTPSYNRDNSIS CCCCCCCCCCCCCCC	18.54	28066266
920	Phosphorylation	PSYNRDNSISPESDV CCCCCCCCCCCCCCC	28.82	27087446
922	Phosphorylation	YNRDNSISPESDVDT CCCCCCCCCCCCCCC	23.57	25521595
925	Phosphorylation	DNSISPESDVDTAST CCCCCCCCCCCCHHH	46.44	27087446
929	Phosphorylation	SPESDVDTASTISLV CCCCCCCCHHHHHHH	23.50	25619855
931	Phosphorylation	ESDVDTASTISLVTG CCCCCCHHHHHHHCC	28.50	25619855
932	Phosphorylation	SDVDTASTISLVTGE CCCCCHHHHHHHCCC	16.48	25619855
934	Phosphorylation	VDTASTISLVTGETE CCCHHHHHHHCCCCC	19.51	25619855
937	Phosphorylation	ASTISLVTGETERKS HHHHHHHCCCCCCCC	34.29	25619855
940	Phosphorylation	ISLVTGETERKSTQK HHHHCCCCCCCCCHH	42.29	25619855
950	Phosphorylation	KSTQKRKSFTSLYKD CCCHHCHHHHHHHHC	37.48	25521595
952	Phosphorylation	TQKRKSFTSLYKDRC CHHCHHHHHHHHCCC	25.55	25521595
953	Phosphorylation	QKRKSFTSLYKDRCS HHCHHHHHHHHCCCC	27.91	21743459
955	Phosphorylation	RKSFTSLYKDRCSTS CHHHHHHHHCCCCCC	15.60	28725479
960	Phosphorylation	SLYKDRCSTSSPSKD HHHHCCCCCCCCCCC	32.02	25266776
961	Phosphorylation	LYKDRCSTSSPSKDV HHHCCCCCCCCCCCC	36.53	24759943
962	Phosphorylation	YKDRCSTSSPSKDVT HHCCCCCCCCCCCCC	24.77	25263469
963	Phosphorylation	KDRCSTSSPSKDVTK HCCCCCCCCCCCCCC	33.03	25263469
965	Phosphorylation	RCSTSSPSKDVTKSG CCCCCCCCCCCCCCC	43.36	25266776
983	Phosphorylation	KIEKKAKSRSADIGA HHHHHHHHCCCCCHH	36.01	29899451
985	Phosphorylation	EKKAKSRSADIGARA HHHHHHCCCCCHHHC	37.07	22067460
1008	Phosphorylation	SGRIRQPSIDLTDDD CCCCCCCCCCCCCCC	22.01	27087446
1012	Phosphorylation	RQPSIDLTDDDQTSS CCCCCCCCCCCCCCC	33.37	27087446
1017	Phosphorylation	DLTDDDQTSSVPHSA CCCCCCCCCCCCHHH	29.93	25619855
1018	Phosphorylation	LTDDDQTSSVPHSAI CCCCCCCCCCCHHHH	24.57	25619855
1019	Phosphorylation	TDDDQTSSVPHSAIS CCCCCCCCCCHHHHH	42.95	25619855
1023	Phosphorylation	QTSSVPHSAISDIMS CCCCCCHHHHHHHHC	22.64	25619855
1026	Phosphorylation	SVPHSAISDIMSSDQ CCCHHHHHHHHCCCC	22.32	25619855
1030	Phosphorylation	SAISDIMSSDQETYS HHHHHHHCCCCCEEC	30.97	25619855
1031	Phosphorylation	AISDIMSSDQETYSC HHHHHHCCCCCEECC	26.40	25619855
1040	Phosphorylation	QETYSCKSHGRTPLT CCEECCCCCCCCCCC	35.19	26824392
1044	Phosphorylation	SCKSHGRTPLTSADE CCCCCCCCCCCCCCC	27.52	29899451
1047	Phosphorylation	SHGRTPLTSADEHNI CCCCCCCCCCCCCCC	24.07	25521595
1048	Phosphorylation	HGRTPLTSADEHNIH CCCCCCCCCCCCCCH	41.21	26824392
1066	Phosphorylation	EGGKATKSKTSPVAS CCCCCCCCCCCCCCC	36.49	25521595
1068	Phosphorylation	GKATKSKTSPVASGS CCCCCCCCCCCCCCC	45.41	24453211
1069	Phosphorylation	KATKSKTSPVASGST CCCCCCCCCCCCCCC	22.55	26824392
1073	Phosphorylation	SKTSPVASGSTSKST CCCCCCCCCCCCCCC	33.25	29899451
1075	Phosphorylation	TSPVASGSTSKSTTL CCCCCCCCCCCCCCC	27.32	29899451
1081	Phosphorylation	GSTSKSTTLPRPRPT CCCCCCCCCCCCCCC	41.68	21454597
1088	Phosphorylation	TLPRPRPTRTSLLRR CCCCCCCCHHHHHHH	48.10	22817900
1090	Phosphorylation	PRPRPTRTSLLRRAR CCCCCCHHHHHHHHH	26.63	22817900
1091	Phosphorylation	RPRPTRTSLLRRARL CCCCCHHHHHHHHHH	23.32	22817900
1102	Phosphorylation	RARLGEASDSELADA HHHHCCCCHHHHCHH	37.05	24925903
1104	Phosphorylation	RLGEASDSELADADK HHCCCCHHHHCHHHH	31.82	24925903
1113	Phosphorylation	LADADKASVASEVST HCHHHHHHHCCCCCC	24.77	25619855
1116	Phosphorylation	ADKASVASEVSTTSS HHHHHHCCCCCCCCC	36.05	25619855
1119	Phosphorylation	ASVASEVSTTSSTSK HHHCCCCCCCCCCCC	23.16	25619855
1120	Phosphorylation	SVASEVSTTSSTSKP HHCCCCCCCCCCCCC	35.55	25619855
1121	Phosphorylation	VASEVSTTSSTSKPP HCCCCCCCCCCCCCC	17.11	25619855
1122	Phosphorylation	ASEVSTTSSTSKPPT CCCCCCCCCCCCCCC	31.54	25619855
1123	Phosphorylation	SEVSTTSSTSKPPTG CCCCCCCCCCCCCCC	34.31	25619855
1124	Phosphorylation	EVSTTSSTSKPPTGR CCCCCCCCCCCCCCC	40.30	25619855
1125	Phosphorylation	VSTTSSTSKPPTGRR CCCCCCCCCCCCCCC	45.15	25619855
1129	Phosphorylation	SSTSKPPTGRRTISR CCCCCCCCCCCEECC	52.42	25619855
1133	Phosphorylation	KPPTGRRTISRIDLL CCCCCCCEECCCHHH	23.19	26643407
1135	Phosphorylation	PTGRRTISRIDLLAQ CCCCCEECCCHHHCC	23.67	21659605
1146	Phosphorylation	LLAQPRRTRLGSLSA HHCCCCCCCCCCCCC	31.37	29514104
1150	Phosphorylation	PRRTRLGSLSARSDS CCCCCCCCCCCCCCC	24.60	25521595
1152	Phosphorylation	RTRLGSLSARSDSEA CCCCCCCCCCCCCCC	24.27	25521595
1155	Phosphorylation	LGSLSARSDSEATIS CCCCCCCCCCCCEEC	45.25	25521595
1157	Phosphorylation	SLSARSDSEATISRS CCCCCCCCCCEECCH	30.31	25521595
1160	Phosphorylation	ARSDSEATISRSSAS CCCCCCCEECCHHHH	18.55	25619855
1162	Phosphorylation	SDSEATISRSSASAR CCCCCEECCHHHHHH	23.04	25619855
1177	Phosphorylation	TAEAVIRSGARLVPS HHHHHHHCCCCCCCC	26.19	29514104
1184	Phosphorylation	SGARLVPSDKLSPRT CCCCCCCCCCCCHHH	39.64	25159016
1188	Phosphorylation	LVPSDKLSPRTRANS CCCCCCCCHHHCHHH	20.34	26824392
1191	Phosphorylation	SDKLSPRTRANSISR CCCCCHHHCHHHHHH	37.20	29514104
1195	Phosphorylation	SPRTRANSISRLSDS CHHHCHHHHHHHCHH	22.43	26824392
1197	Phosphorylation	RTRANSISRLSDSKV HHCHHHHHHHCHHHC	27.30	26745281
1200	Phosphorylation	ANSISRLSDSKVKSM HHHHHHHCHHHCHHC	38.43	25263469
1202	Phosphorylation	SISRLSDSKVKSMSS HHHHHCHHHCHHCCC	35.65	26745281
1208	Phosphorylation	DSKVKSMSSTHGSPS HHHCHHCCCCCCCCC	38.89	28066266
1209	Phosphorylation	SKVKSMSSTHGSPSV HHCHHCCCCCCCCCH	18.78	28066266
1210	Phosphorylation	KVKSMSSTHGSPSVN HCHHCCCCCCCCCHH	23.97	28066266
1213	Phosphorylation	SMSSTHGSPSVNSRW HCCCCCCCCCHHHHC	13.34	30635358
1215	Phosphorylation	SSTHGSPSVNSRWRR CCCCCCCCHHHHCCC	35.31	28066266
1218	Phosphorylation	HGSPSVNSRWRRFPT CCCCCHHHHCCCCCC	30.94	28066266
1225	Phosphorylation	SRWRRFPTDYASTSE HHCCCCCCCCCCCCC	38.64	25619855
1227	Phosphorylation	WRRFPTDYASTSEDE CCCCCCCCCCCCCCC	12.63	25619855
1229	Phosphorylation	RFPTDYASTSEDEFG CCCCCCCCCCCCCCC	26.66	18388127
1230	Phosphorylation	FPTDYASTSEDEFGS CCCCCCCCCCCCCCC	28.15	18388127
1231	Phosphorylation	PTDYASTSEDEFGSN CCCCCCCCCCCCCCC	40.32	18388127
1237	Phosphorylation	TSEDEFGSNRNSPKH CCCCCCCCCCCCCCC	37.63	25619855
1241	Phosphorylation	EFGSNRNSPKHTRLR CCCCCCCCCCCCCCC	31.89	25521595
1249	Phosphorylation	PKHTRLRTSPALKTT CCCCCCCCCCCCCHH	43.59	29895711
1250	Phosphorylation	KHTRLRTSPALKTTR CCCCCCCCCCCCHHC	11.18	25266776
1260	Phosphorylation	LKTTRMQSTGSAMPA CCHHCCCCCCCCCCC	25.95	25266776
1261	Phosphorylation	KTTRMQSTGSAMPAS CHHCCCCCCCCCCCC	20.47	26643407
1263	Phosphorylation	TRMQSTGSAMPASSS HCCCCCCCCCCCCHH	22.83	26643407
1268	Phosphorylation	TGSAMPASSSFKHRI CCCCCCCCHHHHHHH	22.20	26643407
1269	Phosphorylation	GSAMPASSSFKHRIK CCCCCCCHHHHHHHH	41.73	26643407
1270	Phosphorylation	SAMPASSSFKHRIKE CCCCCCHHHHHHHHH	35.50	26643407
1276	Ubiquitination	SSFKHRIKEQEDYIR HHHHHHHHHHHHHHH	53.99	-
1296	Phosphorylation	REEIARISQDLALIA HHHHHHHHHHHHHHH	16.46	27180971
1332	Phosphorylation	TTVSTAATTPGSAID CEEECCCCCCCCCCC	30.93	25338131
1362	Phosphorylation	VDRVFDESLNFRKIP HHHHHHHCCCCCCCC	30.38	28066266
1374	Phosphorylation	KIPPLVHSKTPEGNN CCCCCCCCCCCCCCC	30.64	21454597
1376	Phosphorylation	PPLVHSKTPEGNNGR CCCCCCCCCCCCCCC	29.59	26060331
1384	Phosphorylation	PEGNNGRSVDSRPQP CCCCCCCCCCCCCCC	31.51	27841257
1387	Phosphorylation	NNGRSVDSRPQPAEH CCCCCCCCCCCCCCC	43.64	26060331
1405	Phosphorylation	LTITRRRTWSRDEVM EEEECCCCCCCCHHH	26.44	26239621
1407	Phosphorylation	ITRRRTWSRDEVMGD EECCCCCCCCHHHCC	29.28	26239621
1435	Phosphorylation	IRQSIDKTAGKIRIL HHHHHHHCCCEEEEE	36.57	-
1468	Phosphorylation	SEVPIVKTSSMEISS CCCCEEECCCHHHHH	18.36	20415495
1469	Phosphorylation	EVPIVKTSSMEISSI CCCEEECCCHHHHHH	23.21	29899451
1470	Phosphorylation	VPIVKTSSMEISSIL CCEEECCCHHHHHHH	26.18	20415495
1474	Phosphorylation	KTSSMEISSILQELK ECCCHHHHHHHHHHH	9.68	22817900
1475	Phosphorylation	TSSMEISSILQELKR CCCHHHHHHHHHHHH	32.74	20415495
1515	Phosphorylation	FPNAILPSPPKQKSS CCCCCCCCCCCCCCC	50.84	26745281
1521	Phosphorylation	PSPPKQKSSPVNNHS CCCCCCCCCCCCCCC	37.06	27087446
1522	Phosphorylation	SPPKQKSSPVNNHSS CCCCCCCCCCCCCCC	39.64	25177544
1528	Phosphorylation	SSPVNNHSSPSQTPA CCCCCCCCCCCCCCC	46.17	22942356
1529	Phosphorylation	SPVNNHSSPSQTPAL CCCCCCCCCCCCCCC	22.48	25521595
1531	Phosphorylation	VNNHSSPSQTPALCP CCCCCCCCCCCCCCC	48.94	22942356
1533	Phosphorylation	NHSSPSQTPALCPPE CCCCCCCCCCCCCCC	18.18	25619855
1541	Phosphorylation	PALCPPETRALHPAA CCCCCCCCCCCCHHH	27.32	25619855
1564	Phosphorylation	TEFENAESEADFSIH CCCCCCCCCCCEEEE	35.36	26824392
1585	Phosphorylation	DGEEEDVTVHE---- CCCCCCCCCCC----	28.59	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
562	T	Phosphorylation	Kinase	MAPK1	P63085	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CE170_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CE170_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HERC2_HUMAN	HERC2	physical	20360068
RALY_HUMAN	RALY	physical	20360068
PCM1_HUMAN	PCM1	physical	20360068
PCY1A_HUMAN	PCYT1A	physical	20360068
BEGIN_HUMAN	BEGAIN	physical	20360068
NEUL4_HUMAN	NEURL4	physical	20360068
ZN106_HUMAN	ZNF106	physical	20360068
CCAR2_HUMAN	CCAR2	physical	20360068
WDR62_HUMAN	WDR62	physical	20360068
SSBP_HUMAN	SSBP1	physical	20360068
C170B_HUMAN	CEP170B	physical	20360068
CE170_HUMAN	CEP170	physical	20360068
KIFC3_HUMAN	KIFC3	physical	20360068
SNAPN_HUMAN	SNAPIN	physical	20360068
KIF2A_HUMAN	KIF2A	physical	26496610
KIFC3_HUMAN	KIFC3	physical	26496610
PCM1_HUMAN	PCM1	physical	26496610
KAP2_HUMAN	PRKAR2A	physical	26496610
HERC2_HUMAN	HERC2	physical	26496610
AKA12_HUMAN	AKAP12	physical	26496610
ZBTB5_HUMAN	ZBTB5	physical	26496610
CP131_HUMAN	CEP131	physical	26496610
MABP1_HUMAN	MAPKBP1	physical	26496610
SNAPN_HUMAN	SNAPIN	physical	26496610
PATZ1_HUMAN	PATZ1	physical	26496610
MA7D1_HUMAN	MAP7D1	physical	26496610
CEP72_HUMAN	CEP72	physical	26496610
NEUA_HUMAN	CMAS	physical	26496610
ZN106_HUMAN	ZNF106	physical	26496610
SIN1_HUMAN	MAPKAP1	physical	26496610
MUS81_HUMAN	MUS81	physical	26496610
CDCA3_HUMAN	CDCA3	physical	26496610
CCD77_HUMAN	CCDC77	physical	26496610
NEUL4_HUMAN	NEURL4	physical	26496610
WDR62_HUMAN	WDR62	physical	26496610

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CE170_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-443 AND SER-829, ANDMASS SPECTROMETRY.	19131326 [Abstract]
"The phagosomal proteome in interferon-gamma-activated macrophages."; Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.; Immunity 30:143-154(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-358; SER-1102; SER-1155AND SER-1188, AND MASS SPECTROMETRY.	19144319 [Abstract]
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-355 AND SER-358, ANDMASS SPECTROMETRY.	19367708 [Abstract]