CC151_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC151_HUMAN
• UniProt AC: A5D8V7
• Protein Name: Coiled-coil domain-containing protein 151
• Gene Name: CCDC151
• Organism: Homo sapiens (Human).
• Sequence Length: 595
• Subcellular Localization: Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium axoneme .
• Protein Description: Ciliary protein involved in outer dynein arm assembly and required for motile cilia function..
• Protein Sequence: MTSPLCRAASANALPPQDQASTPSSRVKGREASGKPSHLRGKGTAQAWTPGRSKGGSFHRGAGKPSVHSQVAELHKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIREWKWEKPYLKNRTGQALEHLDHRLREKVKQQNALRHQVVLRQRRLEELQLQHSLRLLEMAEAQNRHTEVAKTMRNLENRLEKAQMKAQEAEHITSVYLQLKAYLMDESLNLENRLDSMEAEVVRTKHELEALHVVNQEALNARDIAKNQLQYLEETLVRERKKRERYISECKKRAEEKKLENERMERKTHREHLLLQSDDTIQDSLHAKEEELRQRWSMYQMEVIFGKVKDATGTDETHSLVRRFLAQGDTFAQLETLKSENEQTLVRLKQEKQQLQRELEDLKYSGEATLVSQQKLQAEAQERLKKEERRHAEAKDQLERALRAMQVAKDSLEHLASKLIHITVEDGRFAGKELDPQADNYVPNLLGLVEEKLLKLQAQLQGHDVQEMLCHIANREFLASLEGRLPEYNTRIALPLATSKDKFFDEESEEEDNEVVTRASLKIRSQKLIESHKKHRRSRRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
392	Acetylation	FAQLETLKSENEQTL HHHHHHHHCCCHHHH	64.24	25038526

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC151_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC151_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC151_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924
SUV91_HUMAN	SUV39H1	physical	23455924
SUV92_HUMAN	SUV39H2	physical	23455924
TXLNB_HUMAN	TXLNB	physical	25416956
HERC2_HUMAN	HERC2	physical	26186194
GOGA5_HUMAN	GOLGA5	physical	26186194
IFT46_HUMAN	IFT46	physical	26186194
COMD4_HUMAN	COMMD4	physical	26186194
GOPC_HUMAN	GOPC	physical	26186194
IFT88_HUMAN	IFT88	physical	26186194
RGPD5_HUMAN	RGPD5	physical	26186194
CENPH_HUMAN	CENPH	physical	26186194
IFT74_HUMAN	IFT74	physical	26186194
CCD22_HUMAN	CCDC22	physical	26186194
COMD3_HUMAN	COMMD3	physical	26186194
IFT81_HUMAN	IFT81	physical	26186194
FBXL4_HUMAN	FBXL4	physical	26186194
COMD2_HUMAN	COMMD2	physical	26186194
COMD8_HUMAN	COMMD8	physical	26186194
IFT22_HUMAN	IFT22	physical	26186194
NSE4A_HUMAN	NSMCE4A	physical	26186194
MTFR1_HUMAN	MTFR1	physical	26186194
SNAPN_HUMAN	SNAPIN	physical	26186194
NEUL4_HUMAN	NEURL4	physical	26186194
IFT88_HUMAN	IFT88	physical	28514442
CENPH_HUMAN	CENPH	physical	28514442
IFT46_HUMAN	IFT46	physical	28514442
IFT22_HUMAN	IFT22	physical	28514442
IFT74_HUMAN	IFT74	physical	28514442
NSE4A_HUMAN	NSMCE4A	physical	28514442
CCD22_HUMAN	CCDC22	physical	28514442
COMD8_HUMAN	COMMD8	physical	28514442
GOGA5_HUMAN	GOLGA5	physical	28514442
RGPD5_HUMAN	RGPD5	physical	28514442
COMD3_HUMAN	COMMD3	physical	28514442
SNAPN_HUMAN	SNAPIN	physical	28514442
IFT81_HUMAN	IFT81	physical	28514442
FBXL4_HUMAN	FBXL4	physical	28514442
COMD2_HUMAN	COMMD2	physical	28514442
MTFR1_HUMAN	MTFR1	physical	28514442
CE170_HUMAN	CEP170	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.