ZNF20_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF20_HUMAN
• UniProt AC: P17024
• Protein Name: Zinc finger protein 20
• Gene Name: ZNF20
• Organism: Homo sapiens (Human).
• Sequence Length: 532
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MMFQDSVAFEDVAVSFTQEEWALLDPSQKNLYRDVMQETFKNLTSVGKTWKVQNIEDEYKNPRRNLSLMREKLCESKESHHCGESFNQIADDMLNRKTLPGITPCESSVCGEVGTGHSSLNTHIRADTGHKSSEYQEYGENPYRNKECKKAFSYLDSFQSHDKACTKEKPYDGKECTETFISHSCIQRHRVMHSGDGPYKCKFCGKAFYFLNLCLIHERIHTGVKPYKCKQCGKAFTRSTTLPVHERTHTGVNADECKECGNAFSFPSEIRRHKRSHTGEKPYECKQCGKVFISFSSIQYHKMTHTGEKPYECKQCGKAFRCGSHLQKHGRTHTGEKPYECRQCGKAFRCTSDLQRHEKTHTEDKPYGCKQCGKGFRCASQLQIHERTHSGEKPHECKECGKVFKYFSSLRIHERTHTGEKPHECKQCGKAFRYFSSLHIHERTHTGDKPYECKVCGKAFTCSSSIRYHERTHTGEKPYECKHCGKAFISNYIRYHERTHTGEKPYQCKQCGKAFIRASSCREHERTHTINR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	DPSQKNLYRDVMQET CHHHHHHHHHHHHHH	17.73	-
44	Phosphorylation	QETFKNLTSVGKTWK HHHHHCCCCCCCCEE	30.66	30576142
45	Phosphorylation	ETFKNLTSVGKTWKV HHHHCCCCCCCCEEE	31.85	30576142
51	Acetylation	TSVGKTWKVQNIEDE CCCCCCEEEECHHHH	38.89	7676341
59	Phosphorylation	VQNIEDEYKNPRRNL EECHHHHHCCHHHCH	28.52	30576142
128	Phosphorylation	NTHIRADTGHKSSEY HHCCCCCCCCCCHHH	39.95	-
132	Phosphorylation	RADTGHKSSEYQEYG CCCCCCCCHHHHHCC	23.80	-
133	Phosphorylation	ADTGHKSSEYQEYGE CCCCCCCHHHHHCCC	45.16	-
143	Phosphorylation	QEYGENPYRNKECKK HHCCCCCCCCHHHHH	38.10	-
194	Phosphorylation	QRHRVMHSGDGPYKC HHCCEEECCCCCCCC	22.08	-
286	Sumoylation	GEKPYECKQCGKVFI CCCCCCCCCCCCEEE	36.36	-
286	Sumoylation	GEKPYECKQCGKVFI CCCCCCCCCCCCEEE	36.36	-
304	Phosphorylation	SIQYHKMTHTGEKPY EEEEEECCCCCCCCE	22.53	27251275
306	Phosphorylation	QYHKMTHTGEKPYEC EEEECCCCCCCCEEC	37.56	29496963
306	Ubiquitination	QYHKMTHTGEKPYEC EEEECCCCCCCCEEC	37.56	22505724
309	Ubiquitination	KMTHTGEKPYECKQC ECCCCCCCCEECCCC	55.00	22505724
314	Sumoylation	GEKPYECKQCGKAFR CCCCEECCCCCCEEE	36.36	-
314	Sumoylation	GEKPYECKQCGKAFR CCCCEECCCCCCEEE	36.36	-
332	Phosphorylation	HLQKHGRTHTGEKPY HHHHCCCCCCCCCCC	28.51	-
334	Phosphorylation	QKHGRTHTGEKPYEC HHCCCCCCCCCCCCH	46.56	-
409	Phosphorylation	KVFKYFSSLRIHERT HHHHHHHHCEEEECC	16.27	24719451
416	Phosphorylation	SLRIHERTHTGEKPH HCEEEECCCCCCCCC	22.32	-
418	Phosphorylation	RIHERTHTGEKPHEC EEEECCCCCCCCCHH	46.56	-
468	Phosphorylation	TCSSSIRYHERTHTG EECCEEEEECCCCCC	13.33	29083192
472	Phosphorylation	SIRYHERTHTGEKPY EEEEECCCCCCCCCC	22.32	29396449
474	Ubiquitination	RYHERTHTGEKPYEC EEECCCCCCCCCCCC	46.56	22505724
474	Phosphorylation	RYHERTHTGEKPYEC EEECCCCCCCCCCCC	46.56	29496963
477	Ubiquitination	ERTHTGEKPYECKHC CCCCCCCCCCCCCCC	55.00	22505724
479	Phosphorylation	THTGEKPYECKHCGK CCCCCCCCCCCCCCC	45.05	29083192
490	Phosphorylation	HCGKAFISNYIRYHE CCCCHHHHHHHHHHC	19.68	20363803
492	Phosphorylation	GKAFISNYIRYHERT CCHHHHHHHHHHCCC	4.68	22210691
495	Phosphorylation	FISNYIRYHERTHTG HHHHHHHHHCCCCCC	9.85	22210691
499	Phosphorylation	YIRYHERTHTGEKPY HHHHHCCCCCCCCCE	22.32	-
501	Phosphorylation	RYHERTHTGEKPYQC HHHCCCCCCCCCEEC	46.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF20_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF20_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF20_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HAP1_HUMAN	HAP1	physical	16169070
KRT38_HUMAN	KRT38	physical	25416956
MTUS2_HUMAN	MTUS2	physical	25416956
CCDB1_HUMAN	CCNDBP1	physical	25416956
CC136_HUMAN	CCDC136	physical	25416956
C102B_HUMAN	CCDC102B	physical	25416956
KR412_HUMAN	KRTAP4-12	physical	25416956
LZTS2_HUMAN	LZTS2	physical	25416956
KRA42_HUMAN	KRTAP4-2	physical	25416956
FSD2_HUMAN	FSD2	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.