TPC2L_HUMAN - dbPTM
TPC2L_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TPC2L_HUMAN
UniProt AC Q9UL33
Protein Name Trafficking protein particle complex subunit 2-like protein
Gene Name TRAPPC2L
Organism Homo sapiens (Human).
Sequence Length 140
Subcellular Localization Cytoplasm, perinuclear region . Endoplasmic reticulum . Golgi apparatus .
Protein Description May play a role in vesicular transport from endoplasmic reticulum to Golgi..
Protein Sequence MAVCIAVIAKENYPLYIRSTPTENELKFHYMVHTSLDVVDEKISAMGKALVDQRELYLGLLYPTEDYKVYGYVTNSKVKFVMVVDSSNTALRDNEIRSMFRKLHNSYTDVMCNPFYNPGDRIQSSRAFDNMVTSMMIQVC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
30PhosphorylationENELKFHYMVHTSLD
CCCEEEEEEEEECHH		12.1723663014
34PhosphorylationKFHYMVHTSLDVVDE
EEEEEEEECHHHHHH		21.4123663014
48UbiquitinationEKISAMGKALVDQRE
HHHHHHHHHHHHHHH		26.0121890473
48 (in isoform 1)Ubiquitination-26.0121890473
48 (in isoform 2)Ubiquitination-26.0121890473
70PhosphorylationPTEDYKVYGYVTNSK
ECCCEEEEEEECCCC		9.8921406692
72PhosphorylationEDYKVYGYVTNSKVK
CCEEEEEEECCCCEE		6.0921406692
74PhosphorylationYKVYGYVTNSKVKFV
EEEEEEECCCCEEEE		25.8721406692
76PhosphorylationVYGYVTNSKVKFVMV
EEEEECCCCEEEEEE		29.4721406692
77UbiquitinationYGYVTNSKVKFVMVV
EEEECCCCEEEEEEE		52.06-
86PhosphorylationKFVMVVDSSNTALRD
EEEEEECCCCCCCCH		17.5520071362
89PhosphorylationMVVDSSNTALRDNEI
EEECCCCCCCCHHHH		29.0820071362
102UbiquitinationEIRSMFRKLHNSYTD
HHHHHHHHHHHHCCC		42.72-
106PhosphorylationMFRKLHNSYTDVMCN
HHHHHHHHCCCCCCC		20.75-
107PhosphorylationFRKLHNSYTDVMCNP
HHHHHHHCCCCCCCC		16.57-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TPC2L_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TPC2L_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TPC2L_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TPPC3_HUMANTRAPPC3physical
21453443
TPC13_HUMANTRAPPC13physical
21453443
TPPC8_HUMANTRAPPC8physical
21453443
TPPC8_HUMANTRAPPC8physical
21525244
TPC10_HUMANTRAPPC10physical
21525244
TPPC9_HUMANTRAPPC9physical
21525244
TPC12_HUMANTRAPPC12physical
21525244
TPC11_HUMANTRAPPC11physical
21525244
TPPC3_HUMANTRAPPC3physical
21525244
TPC3L_HUMANTRAPPC3Lphysical
21525244
TPC6A_HUMANTRAPPC6Aphysical
21525244
TPC6B_HUMANTRAPPC6Bphysical
21525244
TPC2L_HUMANTRAPPC2Lphysical
21525244
A4_HUMANAPPphysical
21832049
REPS1_HUMANREPS1physical
25416956
CE57L_HUMANCEP57L1physical
25416956
TPC10_HUMANTRAPPC10physical
27173435
PDLI7_HUMANPDLIM7physical
27173435
M21D2_HUMANMB21D2physical
27173435
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TPC2L_HUMAN

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Related Literatures of Post-Translational Modification

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