PSB1_DROME - dbPTM
PSB1_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PSB1_DROME
UniProt AC P40304
Protein Name Proteasome subunit beta type-1
Gene Name Prosbeta6
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 235
Subcellular Localization Cytoplasm . Nucleus.
Protein Description The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity..
Protein Sequence MSRLGFEQFPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of PSB1_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PSB1_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PSB1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PSB1_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PSA4_DROMEProsalpha3physical
22036573
PSA1_DROMEProsalpha6physical
22036573
PSB4_DROMEProsbeta7physical
22036573
PSA2_DROMEProsalpha2physical
22036573
PSA6_DROMEProsalpha1physical
22036573
PSB3_DROMEProsbeta3physical
22036573
PSA3_DROMEProsalpha7physical
22036573
PSA5_DROMEProsalpha5physical
22036573
PSA71_DROMEProsalpha4physical
22036573
PRS8_DROMERpt6physical
22036573
PRS4_DROMERpt2physical
22036573
PSMD1_DROMERpn2physical
22036573
ADRM1_DROMERpn13physical
22036573
PSD11_DROMERpn6physical
22036573
PSB2_DROMEProsbeta4R2physical
22036573
PSMD7_DROMERpn8physical
22036573
PSDE_DROMERpn11physical
22036573
C4G15_DROMECyp4g15physical
22036573
KLC_DROMEKlcphysical
22036573
PSMD6_DROMERpn7physical
22036573
HLES_DROMEHgenetic
16410550
NUMB_DROMEnumbgenetic
15798180
PSA2_DROMEProsalpha2genetic
16648584
HLES_DROMEHgenetic
10500185

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PSB1_DROME

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Related Literatures of Post-Translational Modification

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