dbPTM

OTUD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OTUD4_HUMAN
UniProt AC	Q01804
Protein Name	OTU domain-containing protein 4
Gene Name	OTUD4 {ECO:0000312\|HGNC:HGNC:24949}
Organism	Homo sapiens (Human).
Sequence Length	1114
Subcellular Localization	Cytoplasm . Nucleus . Primarily cytoplasmic.
Protein Description	Deubiquitinase which hydrolyzes the isopeptide bond between the ubiquitin C-terminus and the lysine epsilon-amino group of the target protein. [PubMed: 23827681]
Protein Sequence	MEAAVGVPDGGDQGGAGPREDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIVMELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRPFRGDRRRSGMGDGHRGQHT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEAAVGVP -------CCCCCCCC	36.30	22223895
41	Acetylation	LYRKLVAKDGSCLFR HHHHHHCCCCCHHHH	55.96	23749302
41	Ubiquitination	LYRKLVAKDGSCLFR HHHHHHCCCCCHHHH	55.96	33845483
55	Phosphorylation	RAVAEQVLHSQSRHV HHHHHHHHHCCCCCH	3.00	27251275
120	Phosphorylation	YRKDFIIYREPNVSP HCCCEEEEECCCCCH	12.24	29395066
126	Phosphorylation	IYREPNVSPSQVTEN EEECCCCCHHHCCCC	26.02	29395066
128	Phosphorylation	REPNVSPSQVTENNF ECCCCCHHHCCCCCC	29.76	29395066
131	Phosphorylation	NVSPSQVTENNFPEK CCCHHHCCCCCCCCE	25.92	29395066
144	Phosphorylation	EKVLLCFSNGNHYDI CEEEEEEECCCEEEE	42.71	27251275
147	Ubiquitination	LLCFSNGNHYDIVYP EEEEECCCEEEEEEE	34.49	27667366
154	Ubiquitination	NHYDIVYPIKYKESS CEEEEEEEEECCHHH	13.00	27667366
160	Phosphorylation	YPIKYKESSAMCQSL EEEECCHHHHHHHHH	21.17	-
161	Phosphorylation	PIKYKESSAMCQSLL EEECCHHHHHHHHHH	22.55	-
166	Phosphorylation	ESSAMCQSLLYELLY HHHHHHHHHHHHHHH	18.53	29395066
169	Phosphorylation	AMCQSLLYELLYEKV HHHHHHHHHHHHHHH	15.15	-
190	Phosphorylation	KIVMELDTLEVADED HHHHHHCCEEECCCC	37.13	29514088
199	Phosphorylation	EVADEDNSEISDSED EECCCCCCCCCCCCC	48.94	29514088
202	Phosphorylation	DEDNSEISDSEDDSC CCCCCCCCCCCCCCH	30.91	29395066
204	Phosphorylation	DNSEISDSEDDSCKS CCCCCCCCCCCCHHH	35.81	29395066
208	Phosphorylation	ISDSEDDSCKSKTAA CCCCCCCCHHHHHHH	35.45	29514088
212	Ubiquitination	EDDSCKSKTAAAAAD CCCCHHHHHHHHHHC	27.90	27667366
219	Ubiquitination	KTAAAAADVNGFKPL HHHHHHHCCCCCCCC	29.68	27667366
234	Ubiquitination	SGNEQLKNNGNSTSL CCCHHHHHCCCCCCC	49.81	29967540
257	Ubiquitination	SLNPAVYRNVEYEIW HCCHHHHCCCEEEEE	17.18	29967540
266	Methylation	VEYEIWLKSKQAQQK CEEEEEECCHHHHHH	28.03	115974523
278	Ubiquitination	QQKRDYSIAAGLQYE HHHCCCCHHHCCEEE	6.91	29967540
282	Ubiquitination	DYSIAAGLQYEVGDK CCCHHHCCEEEECCE	31.27	29967540
284	Phosphorylation	SIAAGLQYEVGDKCQ CHHHCCEEEECCEEE	27.36	21945579
299	Acetylation	VRLDHNGKFLNADVQ EEECCCCCCCCEEEE	7.24	26051181
329	Ubiquitination	KKHTSKNLKAPPPES CCCCCCCCCCCCCHH	69.14	2190698
330 (in isoform 1)	Ubiquitination	-	25.62	21906983
341	Phosphorylation	PESWNTVSGKKMKKP CHHCCCCCCCCCCCC	29.30	25159151
343	Acetylation	SWNTVSGKKMKKPST HCCCCCCCCCCCCCC	60.52	25953088
344	Acetylation	WNTVSGKKMKKPSTS CCCCCCCCCCCCCCC	8.43	7298789
344	Ubiquitination	WNTVSGKKMKKPSTS CCCCCCCCCCCCCCC	8.43	29967540
349	Phosphorylation	GKKMKKPSTSGQNFH CCCCCCCCCCCCCCC	45.46	29978859
350	Phosphorylation	KKMKKPSTSGQNFHS CCCCCCCCCCCCCCC	42.60	25159151
351	Phosphorylation	KMKKPSTSGQNFHSD CCCCCCCCCCCCCCC	26.92	24719451
361	Phosphorylation	NFHSDVDYRGPKNPS CCCCCCCCCCCCCCC	50.93	-
368	Phosphorylation	YRGPKNPSKPIKAPS CCCCCCCCCCCCCCC	52.60	27470641
375	Phosphorylation	SKPIKAPSALPPRLQ CCCCCCCCCCCCCCC	24.03	20068231
378	Phosphorylation	IKAPSALPPRLQHPS CCCCCCCCCCCCCCC	50.92	24719451
380	Methylation	APSALPPRLQHPSGV CCCCCCCCCCCCCCC	7.27	115486099
385	Phosphorylation	PPRLQHPSGVRQHAF CCCCCCCCCCCCCCC	24.07	20068231
393	Phosphorylation	GVRQHAFSSHSSGSQ CCCCCCCCCCCCCCC	22.42	30576142
394	Phosphorylation	VRQHAFSSHSSGSQS CCCCCCCCCCCCCCC	25.45	30576142
396	Phosphorylation	QHAFSSHSSGSQSQK CCCCCCCCCCCCCHH	36.72	30576142
399	Phosphorylation	FSSHSSGSQSQKFSS CCCCCCCCCCHHCCH	54.10	30576142
401	Phosphorylation	SHSSGSQSQKFSSEH CCCCCCCCHHCCHHC	43.08	-
412	Phosphorylation	SSEHKNLSRTPSQII CHHCCCCCCCHHHHH	54.55	25159151
414	Phosphorylation	EHKNLSRTPSQIIRK HCCCCCCCHHHHHCC	24.11	30266825
416	Phosphorylation	KNLSRTPSQIIRKPD CCCCCCHHHHHCCCC	36.01	23401153
434	Phosphorylation	VEDFDHTSRESNYFG HHCCCCCCHHHCCCC	53.14	21712546
437	Phosphorylation	FDHTSRESNYFGLSP CCCCCHHHCCCCCCH	31.25	28796482
438	Phosphorylation	DHTSRESNYFGLSPE CCCCHHHCCCCCCHH	14.33	17389395
439	Phosphorylation	HTSRESNYFGLSPEE CCCHHHCCCCCCHHH	10.44	23927012
443	Phosphorylation	ESNYFGLSPEERREK HHCCCCCCHHHHHHH	53.13	19664994
452	Phosphorylation	EERREKQAIEESRLL HHHHHHHHHHHHHHH	5.82	27251275
460	Phosphorylation	IEESRLLYEIQNRDE HHHHHHHHHHHCCCC	37.76	21945579
474	Phosphorylation	EQAFPALSSSSVNQS CCHHHHCCCCCCCCC	27.73	26074081
475	Phosphorylation	QAFPALSSSSVNQSA CHHHHCCCCCCCCCC	34.62	21945579
476	Phosphorylation	AFPALSSSSVNQSAS HHHHCCCCCCCCCCC	27.34	26074081
477	Phosphorylation	FPALSSSSVNQSASQ HHHCCCCCCCCCCCC	9.03	21945579
480	Phosphorylation	LSSSSVNQSASQSSN CCCCCCCCCCCCCCC	25.37	27251275
481	Phosphorylation	SSSSVNQSASQSSNP CCCCCCCCCCCCCCC	11.22	24719451
483	Phosphorylation	SSVNQSASQSSNPCV CCCCCCCCCCCCCCC	51.07	26074081
485	Phosphorylation	VNQSASQSSNPCVQR CCCCCCCCCCCCCHH	36.83	21945579
486	Phosphorylation	NQSASQSSNPCVQRK CCCCCCCCCCCCHHC	38.96	21945579
492	Phosphorylation	SSNPCVQRKSSHVGD CCCCCCHHCCCCCCC	38.94	27251275
494	Phosphorylation	NPCVQRKSSHVGDRK CCCCHHCCCCCCCCC	25.81	23882029
495	Phosphorylation	PCVQRKSSHVGDRKG CCCHHCCCCCCCCCC	34.37	26074081
503	Phosphorylation	HVGDRKGSRRRMDTE CCCCCCCCCCCCCHH	38.60	23882029
517	Phosphorylation	EERKDKDSIHGHSQL HHHCCCCCCCCCCCC	6.91	28555341
531	Phosphorylation	LDKRPEPSTLENITD CCCCCCCCCCCCCCC	49.13	20873877
532	Phosphorylation	DKRPEPSTLENITDD CCCCCCCCCCCCCCC	5.79	20873877
537	Phosphorylation	PSTLENITDDKYATV CCCCCCCCCCCCCCC	46.75	20873877
541	Phosphorylation	ENITDDKYATVSSPS CCCCCCCCCCCCCCC	13.78	23927012
543	Phosphorylation	ITDDKYATVSSPSKS CCCCCCCCCCCCCCC	3.98	30266825
544	Phosphorylation	TDDKYATVSSPSKSK CCCCCCCCCCCCCCC	31.98	21406692
545	Phosphorylation	DDKYATVSSPSKSKK CCCCCCCCCCCCCCC	28.93	23401153
546	Phosphorylation	DKYATVSSPSKSKKL CCCCCCCCCCCCCCC	37.97	22167270
547	Phosphorylation	KYATVSSPSKSKKLE CCCCCCCCCCCCCCC	52.05	21406692
548	Phosphorylation	YATVSSPSKSKKLEC CCCCCCCCCCCCCCC	70.45	30266825
550	Phosphorylation	TVSSPSKSKKLECPS CCCCCCCCCCCCCCC	66.18	26074081
557	Phosphorylation	SKKLECPSPAEQKPA CCCCCCCCCCCCCCC	25.59	25849741
568	Phosphorylation	QKPAEHVSLSNPAPL CCCCCCCCCCCCCCE	5.80	26074081
578	Phosphorylation	NPAPLLVSPEVHLTP CCCCEEECCCCCCCC	39.90	26074081
607	O-linked_Glycosylation	EPTTFGPTGVPAPIP CCCCCCCCCCCCCCC	26.92	23301498
617	O-linked_Glycosylation	PAPIPVLSVTQTLTT CCCCCEEEEEEEEEC	3.93	23301498
619	O-linked_Glycosylation	PIPVLSVTQTLTTGP CCCEEEEEEEEECCC	32.15	23301498
621	O-linked_Glycosylation	PVLSVTQTLTTGPDS CEEEEEEEEECCCCC	2.65	23301498
629	Ubiquitination	LTTGPDSAVSQAHLT EECCCCCCCCCCCCC	5.16	29967540
657	O-linked_Glycosylation	PLMPLPQTLSLYQDP CCCCCCCCEECCCCC	2.53	23301498
710	Phosphorylation	FNLGVKAYSCPMWAP HHCCCCCCCCCCCCC	19.32	-
720	Phosphorylation	PMWAPHSYLYPLHQA CCCCCCCHHHHHHHH	3.88	-
827	Phosphorylation	GQLLHADYEESLSGK CCEEECCHHHHCCCC	41.48	19651622
828	Phosphorylation	QLLHADYEESLSGKN CEEECCHHHHCCCCC	51.23	32142685
835	Phosphorylation	EESLSGKNMFPQPSF HHHCCCCCCCCCCCC	6.21	27251275
840	Phosphorylation	GKNMFPQPSFGPNPF CCCCCCCCCCCCCCC	37.27	27251275
857	Phosphorylation	PVPIAPPFFPHVWYG CCCCCCCCCCCEECC	5.15	27251275
878	Phosphorylation	IENPVMRQNIVLPSD CCCCCCCCCEEECCC	18.90	27251275
892	Phosphorylation	DEKGELDLSLENLDL CCCCCCCEEEECCCC	33.05	21406692
893	Phosphorylation	EKGELDLSLENLDLS CCCCCCEEEECCCCC	7.04	19664994
900	Phosphorylation	SLENLDLSKDCGSVS EEECCCCCCCCCCCC	65.42	22617229
905	Phosphorylation	DLSKDCGSVSTVDEF CCCCCCCCCCCHHCC	3.18	30576142
907	Phosphorylation	SKDCGSVSTVDEFPE CCCCCCCCCHHCCHH	29.80	30576142
908	Phosphorylation	KDCGSVSTVDEFPEA CCCCCCCCHHCCHHH	5.31	-
917	Ubiquitination	DEFPEARGEHVHSLP HCCHHHCCCCCCCCC	36.86	24816145
922	Phosphorylation	ARGEHVHSLPEASVS HCCCCCCCCCCCCCC	2.41	30266825
924	Ubiquitination	GEHVHSLPEASVSSK CCCCCCCCCCCCCCC	59.89	24816145
927	Phosphorylation	VHSLPEASVSSKPDE CCCCCCCCCCCCCCC	10.90	30266825
929	Phosphorylation	SLPEASVSSKPDEGR CCCCCCCCCCCCCCC	46.16	30183078
930	Phosphorylation	LPEASVSSKPDEGRT CCCCCCCCCCCCCCC	49.32	30183078
937	Phosphorylation	SKPDEGRTEQSSQTR CCCCCCCCCCCCCCH	47.29	27251275
940	Phosphorylation	DEGRTEQSSQTRKAD CCCCCCCCCCCHHHC	34.95	19664995
941	Phosphorylation	EGRTEQSSQTRKADT CCCCCCCCCCHHHCH	51.04	16964243
943	Phosphorylation	RTEQSSQTRKADTAL CCCCCCCCHHHCHHH	25.24	27251275
946	Phosphorylation	QSSQTRKADTALASI CCCCCHHHCHHHHCC	35.23	27251275
952	Phosphorylation	KADTALASIPPVAEG HHCHHHHCCCCCCCC	3.58	28555341
958	Phosphorylation	ASIPPVAEGKAHPPT HCCCCCCCCCCCCCC	23.78	24719451
959	Phosphorylation	SIPPVAEGKAHPPTQ CCCCCCCCCCCCCCC	34.72	24719451
975	Ubiquitination	LNRERETVPVELEPK CCCCCCCCCCCCCCH	22.68	23000965
981	Phosphorylation	TVPVELEPKRTIQSL CCCCCCCCHHHHHHH	53.44	24719451
982	Ubiquitination	VPVELEPKRTIQSLK CCCCCCCHHHHHHHH	48.02	23000965
984	Phosphorylation	VELEPKRTIQSLKEK CCCCCHHHHHHHHHH	2.80	28555341
988	Ubiquitination	PKRTIQSLKEKTEKV CHHHHHHHHHHHHCC	63.51	24816145
989	Ubiquitination	KRTIQSLKEKTEKVK HHHHHHHHHHHHCCC	71.19	24816145
1000	O-linked_Glycosylation	EKVKDPKTAADVVSP HCCCCCCCHHHHCCC	14.06	23301498
1000	Phosphorylation	EKVKDPKTAADVVSP HCCCCCCCHHHHCCC	14.06	28985074
1005	Phosphorylation	PKTAADVVSPGANSV CCCHHHHCCCCCCCH	19.91	21406692
1006	Phosphorylation	KTAADVVSPGANSVD CCHHHHCCCCCCCHH	34.01	19664994
1011	Phosphorylation	VVSPGANSVDSRVQR HCCCCCCCHHHHCCC	8.53	23927012
1014	Phosphorylation	PGANSVDSRVQRPKE CCCCCHHHHCCCCCC	24.91	23927012
1020	Acetylation	DSRVQRPKEESSEDE HHHCCCCCCCCCCCH	66.83	7683203
1022	Phosphorylation	RVQRPKEESSEDENE HCCCCCCCCCCCHHH	39.87	21406692
1023	Phosphorylation	VQRPKEESSEDENEV CCCCCCCCCCCHHHH	52.96	19664994
1024	Phosphorylation	QRPKEESSEDENEVS CCCCCCCCCCHHHHH	77.84	19664994
1031	Phosphorylation	SEDENEVSNILRSGR CCCHHHHHHHHHHCC	42.35	22167270
1040	Methylation	ILRSGRSKQFYNQTY HHHHCCCHHHHHCCC	47.50	-
1040	Ubiquitination	ILRSGRSKQFYNQTY HHHHCCCHHHHHCCC	47.50	23000965
1046	Phosphorylation	SKQFYNQTYGSRKYK CHHHHHCCCCCCCCC	11.88	29978859
1046	Ubiquitination	SKQFYNQTYGSRKYK CHHHHHCCCCCCCCC	11.88	23000965
1047	Phosphorylation	KQFYNQTYGSRKYKS HHHHHCCCCCCCCCC	25.10	29978859
1047	Ubiquitination	KQFYNQTYGSRKYKS HHHHHCCCCCCCCCC	25.10	23000965
1049	Phosphorylation	FYNQTYGSRKYKSDW HHHCCCCCCCCCCCC	41.79	28348404
1050	Methylation	YNQTYGSRKYKSDWG HHCCCCCCCCCCCCC	59.74	80702183
1051	Methylation	NQTYGSRKYKSDWGY HCCCCCCCCCCCCCC	18.02	115974507
1053	Methylation	TYGSRKYKSDWGYSG CCCCCCCCCCCCCCC	35.19	115974515
1058	Phosphorylation	KYKSDWGYSGRGGYQ CCCCCCCCCCCCCCC	20.34	-
1059	Phosphorylation	YKSDWGYSGRGGYQH CCCCCCCCCCCCCCC	24.62	-
1061	Methylation	SDWGYSGRGGYQHVR CCCCCCCCCCCCCCC	42.56	30760013
1068	Methylation	RGGYQHVRSEESWKG CCCCCCCCCCCCCCC	44.63	115367967
1072	Phosphorylation	QHVRSEESWKGQPSR CCCCCCCCCCCCCCC	16.45	28857561
1080	Phosphorylation	WKGQPSRSRDEGYQY CCCCCCCCHHHCCCC	44.91	28348404
1085	Phosphorylation	SRSRDEGYQYHRNVR CCCHHHCCCCCCCCC	38.11	-
1087	Phosphorylation	SRDEGYQYHRNVRGR CHHHCCCCCCCCCCC	10.18	21552520
1089	Methylation	DEGYQYHRNVRGRPF HHCCCCCCCCCCCCC	17.96	81450765

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OTUD4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
63	K	ubiquitylation	29395066
Activates 'Lys-63'-specific deubiquitinase activity.
202	S	Phosphorylation	29395066
Phosphorylated on Ser-202 and Ser-204 likely by CSNK2A1-CSNK2A2 serine/threonine-protein kinase complex.
204	S	Phosphorylation	29395066
Phosphorylated on Ser-202 and Ser-204 likely by CSNK2A1-CSNK2A2 serine/threonine-protein kinase complex.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OTUD4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DSG1_HUMAN	DSG1	physical	19615732
FLNC_HUMAN	FLNC	physical	19615732
GALK1_HUMAN	GALK1	physical	19615732
AGAL_HUMAN	GLA	physical	19615732
DNJB1_HUMAN	DNAJB1	physical	19615732
K2C8_HUMAN	KRT8	physical	19615732
K1H1_HUMAN	KRT31	physical	19615732
KT33B_HUMAN	KRT33B	physical	19615732
KRT85_HUMAN	KRT85	physical	19615732
MOG_HUMAN	MOG	physical	19615732
OAT_HUMAN	OAT	physical	19615732
TBA1A_HUMAN	TUBA1A	physical	19615732
KRT36_HUMAN	KRT36	physical	19615732
FXR2_HUMAN	FXR2	physical	19615732
PSA_HUMAN	NPEPPS	physical	19615732
BAG5_HUMAN	BAG5	physical	19615732
GEPH_HUMAN	GPHN	physical	19615732
MYCBP_HUMAN	MYCBP	physical	19615732
NMD3_HUMAN	NMD3	physical	19615732
PAR11_HUMAN	PARP11	physical	19615732
RPTN_HUMAN	RPTN	physical	19615732
UBC_HUMAN	UBC	physical	23827681
ALKB3_HUMAN	ALKBH3	physical	25944111
UBC_HUMAN	UBC	physical	25944111
UBP7_HUMAN	USP7	physical	25944111
USP9X_HUMAN	USP9X	physical	25944111

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OTUD4_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-442; SER-556 AND SER-1005, AND MASSSPECTROMETRY.	19413330 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-442; SER-1005; SER-1022AND SER-1023, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-442; SER-556 AND SER-1005, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-442; SER-1005; SER-1022AND SER-1023, AND MASS SPECTROMETRY.	18669648 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-940, AND MASSSPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1022 AND SER-1023, ANDMASS SPECTROMETRY.	17081983 [Abstract]
"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks."; Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.; Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-438, AND MASSSPECTROMETRY.	17389395 [Abstract]
"Immunoaffinity profiling of tyrosine phosphorylation in cancercells."; Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H.,Zha X.-M., Polakiewicz R.D., Comb M.J.; Nat. Biotechnol. 23:94-101(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-438, AND MASSSPECTROMETRY.	15592455 [Abstract]

show

show

show