CEBPG_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CEBPG_HUMAN
• UniProt AC: P53567
• Protein Name: CCAAT/enhancer-binding protein gamma
• Gene Name: CEBPG
• Organism: Homo sapiens (Human).
• Sequence Length: 150
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. [PubMed: 7665092 Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter.]
• Protein Sequence: MSKISQQNSTPGVNGISVIHTQAHASGLQQVPQLVPAGPGGGGKAVAPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKELSVLKDLFLEHAHNLADNVQSISTENTTADGDNAGQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Sumoylation	-----MSKISQQNST -----CCCCCCCCCC	45.11	28112733
9	Phosphorylation	SKISQQNSTPGVNGI CCCCCCCCCCCCCCE	31.47	25627689
21	Phosphorylation	NGISVIHTQAHASGL CCEEEEECCCCCCCC	19.14	24247654
44	Acetylation	AGPGGGGKAVAPSKQ CCCCCCCCCCCCCCC	42.85	26051181
55	Phosphorylation	PSKQSKKSSPMDRNS CCCCCCCCCCCCCCH	43.33	25627689
56	Phosphorylation	SKQSKKSSPMDRNSD CCCCCCCCCCCCCHH	32.88	25627689
60	Methylation	KKSSPMDRNSDEYRQ CCCCCCCCCHHHHHH	38.00	-
62	Phosphorylation	SSPMDRNSDEYRQRR CCCCCCCHHHHHHHH	32.48	25159151
86	Ubiquitination	SRLKSKQKAQDTLQR HHHHHHHHHHHHHHH	52.32	29967540
98	Ubiquitination	LQRVNQLKEENERLE HHHHHHHHHHHHHHH	53.90	33845483
107	Ubiquitination	ENERLEAKIKLLTKE HHHHHHHHHHHHHHH	30.88	23000965
109	Ubiquitination	ERLEAKIKLLTKELS HHHHHHHHHHHHHHH	36.42	23000965
113	Ubiquitination	AKIKLLTKELSVLKD HHHHHHHHHHHHHHH	57.54	23000965
119	Ubiquitination	TKELSVLKDLFLEHA HHHHHHHHHHHHHHH	50.67	23000965
135	Phosphorylation	NLADNVQSISTENTT HHHHHHHHCCCCCCC	17.77	28450419
137	Phosphorylation	ADNVQSISTENTTAD HHHHHHCCCCCCCCC	34.61	28450419
138	Phosphorylation	DNVQSISTENTTADG HHHHHCCCCCCCCCC	31.42	28450419
141	Phosphorylation	QSISTENTTADGDNA HHCCCCCCCCCCCCC	19.68	28450419
142	Phosphorylation	SISTENTTADGDNAG HCCCCCCCCCCCCCC	34.04	28450419

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CEBPG_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CEBPG_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CEBPG_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AF17_HUMAN	MLLT6	physical	16189514
MYZAP_HUMAN	POLR2M	physical	16189514
GRL1A_HUMAN	POLR2M	physical	16189514
GL1AD_HUMAN	POLR2M	physical	16189514
DDIT3_HUMAN	DDIT3	physical	16189514
DDIT3_HUMAN	DDIT3	physical	12618752
CDK2_HUMAN	CDK2	physical	12757710
BATF3_HUMAN	BATF3	physical	23661758
BATF2_HUMAN	BATF2	physical	23661758
BATF_HUMAN	BATF	physical	23661758
ATF3_HUMAN	ATF3	physical	23661758
UROK_HUMAN	PLAU	physical	23661758
ATF4_HUMAN	ATF4	physical	23661758
FOSL1_HUMAN	FOSL1	physical	23661758
FOS_HUMAN	FOS	physical	23661758
JUN_HUMAN	JUN	physical	23661758
ATF2_HUMAN	ATF2	physical	23661758
CREB3_HUMAN	CREB3	physical	23661758
CEBPE_HUMAN	CEBPE	physical	23661758
CEBPA_HUMAN	CEBPA	physical	23661758
CEBPG_HUMAN	CEBPG	physical	23661758
DDIT3_HUMAN	DDIT3	physical	25416956
KLF5_HUMAN	KLF5	physical	16054042

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.