CAH10_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAH10_HUMAN
• UniProt AC: Q9NS85
• Protein Name: Carbonic anhydrase-related protein 10
• Gene Name: CA10
• Organism: Homo sapiens (Human).
• Sequence Length: 328
• Protein Description: Does not have a catalytic activity..
• Protein Sequence: MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
67	Phosphorylation	CSVGKRQSPVNIETS CCCCCCCCCCCEECC	34.54	-
95	Phosphorylation	NTGGRKVSGTMYNTG ECCCCEEECEEEECC	31.42	24505115
101	Phosphorylation	VSGTMYNTGRHVSLR EECEEEECCCCEEEE	20.36	-
106	Phosphorylation	YNTGRHVSLRLDKEH EECCCCEEEEECHHH	11.14	-
123	Phosphorylation	NISGGPMTYSHRLEE EECCCCCCCCCCCEE	25.63	29759185
124	Phosphorylation	ISGGPMTYSHRLEEI ECCCCCCCCCCCEEE	9.02	29759185
125	Phosphorylation	SGGPMTYSHRLEEIR CCCCCCCCCCCEEEE	7.93	29759185
210	Phosphorylation	DTITRITYKNDAYLL CCCEEEEECCHHHHC	12.86	18491316
299	Phosphorylation	LNNRCIRTNINFSLQ CCCEEEEEECCEEEC	22.12	17081983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CAH10_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAH10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAH10_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
C1TC_HUMAN	MTHFD1	physical	26186194
WDHD1_HUMAN	WDHD1	physical	26186194
T22D1_HUMAN	TSC22D1	physical	26186194
IMPCT_HUMAN	IMPACT	physical	26186194
ASSY_HUMAN	ASS1	physical	26186194
CACO1_HUMAN	CALCOCO1	physical	26186194
TOIP1_HUMAN	TOR1AIP1	physical	26186194
PHYIP_HUMAN	PHYHIP	physical	26186194
CO6A2_HUMAN	COL6A2	physical	26186194
ABT1_HUMAN	ABT1	physical	26186194
INO80_HUMAN	INO80	physical	26186194
ARP10_HUMAN	ACTR10	physical	26186194
MTEF4_HUMAN	MTERF4	physical	26186194
G6PD_HUMAN	G6PD	physical	26186194
LYRM7_HUMAN	LYRM7	physical	26186194
NRBP_HUMAN	NRBP1	physical	26186194
NSUN4_HUMAN	NSUN4	physical	26186194
PSMG1_HUMAN	PSMG1	physical	26186194
KCD15_HUMAN	KCTD15	physical	26186194
PIAS4_HUMAN	PIAS4	physical	26186194
PSMG2_HUMAN	PSMG2	physical	26186194
PSMG3_HUMAN	PSMG3	physical	26186194
PSMG4_HUMAN	PSMG4	physical	26186194
DCTN3_HUMAN	DCTN3	physical	26186194
PPRC1_HUMAN	PPRC1	physical	26186194
MTEF4_HUMAN	MTERF4	physical	28514442
PIAS4_HUMAN	PIAS4	physical	28514442
WDHD1_HUMAN	WDHD1	physical	28514442
PPRC1_HUMAN	PPRC1	physical	28514442
CACO1_HUMAN	CALCOCO1	physical	28514442
IMPCT_HUMAN	IMPACT	physical	28514442
NSUN4_HUMAN	NSUN4	physical	28514442
PHYIP_HUMAN	PHYHIP	physical	28514442
T22D1_HUMAN	TSC22D1	physical	28514442
ASSY_HUMAN	ASS1	physical	28514442
KCD15_HUMAN	KCTD15	physical	28514442
PSMG4_HUMAN	PSMG4	physical	28514442
PSMG2_HUMAN	PSMG2	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
G6PD_HUMAN	G6PD	physical	28514442
INO80_HUMAN	INO80	physical	28514442
PSMG1_HUMAN	PSMG1	physical	28514442
NRBP_HUMAN	NRBP1	physical	28514442
DCTN3_HUMAN	DCTN3	physical	28514442
CO6A2_HUMAN	COL6A2	physical	28514442
C1TC_HUMAN	MTHFD1	physical	28514442
ABT1_HUMAN	ABT1	physical	28514442
TOIP1_HUMAN	TOR1AIP1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• DB00909: Zonisamide

Related Literatures of Post-Translational Modification

Phosphorylation

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-299, AND MASSSPECTROMETRY.
PubMed: 17081983