dbPTM

ARF1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARF1_DROME
UniProt AC	P61209
Protein Name	ADP-ribosylation factor 1
Gene Name	Arf79F
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	182
Subcellular Localization	Golgi apparatus . Cytoplasm, cytosol . Localization to the Golgi is dependent on Asap.
Protein Description	GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. [PubMed: 21976699 Required for cleavage furrow ingression in embryonic cells]
Protein Sequence	MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
2	Myristoylation	------MGNVFANLF ------CCHHHHHHH	38.72	-
147	Phosphorylation	TDKLGLHSLRNRNWY HHHHCCHHCCCCCEE	33.78	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARF1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARF1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARF1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ROA1_DROME	Hrb98DE	physical	14605208
DX39B_DROME	Hel25E	physical	22036573
ACADM_DROME	CG12262	physical	22036573
TCPG_DROME	Cctgamma	physical	22036573
ERD2_DROME	KdelR	physical	22036573
CATL_DROME	Cp1	physical	22036573
ARF2_DROME	Arf102F	physical	22036573
QCR9_DROME	ox	physical	22036573
ARL8_DROME	Gie	physical	22036573
GALE_DROME	Gale	physical	22036573
OST48_DROME	Ost48	physical	22036573
RS15B_DROME	RpS15Ab	physical	22036573
RAB6_DROME	Rab6	physical	22036573
COPB_DROME	betaCOP	physical	22291037
OCAD1_DROME	asrij	physical	24707047
HEM_DROME	Hem	physical	22992458
CYFIP_DROME	Sra-1	physical	22992458
COPG_DROME	gammaCOP	physical	22291037
AP3D_DROME	g	physical	22291037
COPB2_DROME	betaCOP	physical	22291037

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARF1_DROME

Related Literatures of Post-Translational Modification