ROA1_DROME - dbPTM
ROA1_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ROA1_DROME
UniProt AC P07909
Protein Name Heterogeneous nuclear ribonucleoprotein A1
Gene Name Hrb98DE
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 365
Subcellular Localization Nucleus.
Protein Description This protein is a component of ribonucleosomes..
Protein Sequence MVNSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQNDQQGGGGGRGGPGGRAGGNRGNMGGGNYGNQNGGGNWNNGGNNWGNNRGGNDNWGNNSFGGGGGGGGGYGGGNNSWGNNNPWDNGNGGGNFGGGGNNWNNGGNDFGGYQQNYGGGPQRGGGNFNNNRMQPYQGGGGFKAGGGNQGNYGGNNQGFNNGGNNRRY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MVNSNQNQNGN
----CCCCCCCCCCC
28.51-
4 (in isoform 4)Phosphorylation-28.5119429919
12 (in isoform 4)Phosphorylation-45.6619429919
19 (in isoform 4)Phosphorylation-8.2319429919
21 (in isoform 4)Phosphorylation-58.0122668510
23PhosphorylationDDDFPQDSITEPEHM
CCCCCCCCCCCHHHH
26.6022668510
83PhosphorylationFITYSHSSMIDEAQK
EEEECCHHHCCHHHH
17.8422668510
114PhosphorylationVPRQDIDSPNAGATV
CCCCCCCCCCCCHHH
22.0119429919
190AcetylationKQHQLNGKMVDVKKA
EEHHHCCEECCHHHH
34.3821791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ROA1_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ROA1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ROA1_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RB87F_DROMEHrb87Fphysical
22036573
PGPLB_DROMEPGRP-LBphysical
22036573
PARG_DROMEParggenetic
22453833
CADE_DROMEshggenetic
22453833
PELO_DROMEpelophysical
27402862
CADE_DROMEshgphysical
27402862
PUM_DROMEpumphysical
27402862
NANOS_DROMEnosphysical
27402862
HOW_DROMEhowphysical
27402862
FKBP6_DROMEshuphysical
27402862

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ROA1_DROME

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Related Literatures of Post-Translational Modification

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