| UniProt ID | OST48_DROME | |
|---|---|---|
| UniProt AC | Q24319 | |
| Protein Name | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit | |
| Gene Name | Ost48 | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 449 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass type I membrane protein. |
|
| Protein Description | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.. | |
| Protein Sequence | MMWKALLIAVLAIAHCQAVLETDANTLVLLDNLAIRETHSIFFKSLQDRGFKLTYKLADDSSLLLSKYGEYLYKNVIIFAPSVEEFGGDVSVERLAQFVDDGGNVLVAGSEKSGDALREFASECGFELDEENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVLKLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQSGVFHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELVQGEWRAFKASDIQLEFVRIDPFVRTYLKQTNTGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYSTTQVSVRPLEHTQYERFIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDEPVGRAAKEDKKSQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 189 | Ubiquitination | GTGLIADKENPLVLK CCCEECCCCCCHHHE | 50.82 | 31113955 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of OST48_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of OST48_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of OST48_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KRH2_DROME | Kr-h2 | physical | 22036573 | |
| SURF4_DROME | Surf4 | physical | 22036573 | |
| JAGN_DROME | jagn | physical | 22036573 | |
| ATP5J_DROME | ATPsyn-Cf6 | physical | 22036573 | |
| OSTC_DROME | CG9662 | physical | 22036573 | |
| DHRS7_DROME | CG7601 | physical | 22036573 | |
| VATA2_DROME | Vha68-2 | physical | 22036573 | |
| ACADM_DROME | CG12262 | physical | 22036573 | |
| 2AAA_DROME | Pp2A-29B | physical | 22036573 | |
| ATPO_DROME | Oscp | physical | 22036573 | |
| ATPK_DROME | CG4692 | physical | 22036573 | |
| IDH3A_DROME | l(1)G0156 | physical | 22036573 | |
| CCD1P_DROME | Cyp12d1-p | physical | 22036573 | |
| ATPG_DROME | ATPsyn-gamma | physical | 22036573 | |
| RS10B_DROME | RpS10b | physical | 22036573 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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