ZN212_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN212_HUMAN
• UniProt AC: Q9UDV6
• Protein Name: Zinc finger protein 212
• Gene Name: ZNF212
• Organism: Homo sapiens (Human).
• Sequence Length: 495
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAESAPARHRRKRRSTPLTSSTLPSQATEKSSYFQTTEISLWTVVAAIQAVEKKMESQAARLQSLEGRTGTAEKKLADCEKMAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKVSRSLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQELQYTQEGPADLPGEFSCIAEEQAFLSPEQTELWGGQGSSVLLETGPGDSTLEEPVGSRVPSSSRTVGCPKQKSHRQVQLDQECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHSGWGSCTPEEPEESLRPRPRLKPQTKKAKLHQCDVCLRSFSCKVSLVTHQRCHLQEGPSAGQHVQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLLQHQKIHQRERGGLALEPGRPNGLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	RHRRKRRSTPLTSST HHHCCCCCCCCCCCC	38.11	25159151
16	Phosphorylation	HRRKRRSTPLTSSTL HHCCCCCCCCCCCCC	22.10	25159151
19	Phosphorylation	KRRSTPLTSSTLPSQ CCCCCCCCCCCCCCC	23.10	23312004
20	Phosphorylation	RRSTPLTSSTLPSQA CCCCCCCCCCCCCCC	29.07	23312004
21	Phosphorylation	RSTPLTSSTLPSQAT CCCCCCCCCCCCCCC	28.82	23312004
22	Phosphorylation	STPLTSSTLPSQATE CCCCCCCCCCCCCCC	42.32	23312004
28	Phosphorylation	STLPSQATEKSSYFQ CCCCCCCCCCCCCCC	35.99	-
64	Phosphorylation	SQAARLQSLEGRTGT HHHHHHHHHHCCCCC	32.74	-
81	Ubiquitination	KKLADCEKMAVEFGN HHHHHHHHHHHHHHH	38.19	-
99	Phosphorylation	GKWAVLGTLLQEYGL HHHHHHHHHHHHHCH	21.82	-
104	Phosphorylation	LGTLLQEYGLLQRRL HHHHHHHHCHHHHHH	10.50	22817900
166	Phosphorylation	EDWQKELYRNVMESN HHHHHHHHHHHHHHC	10.96	23663014
172	Phosphorylation	LYRNVMESNYETLVS HHHHHHHHCHHHHHE	26.98	23663014
174	Phosphorylation	RNVMESNYETLVSLK HHHHHHCHHHHHEEE	21.41	23663014
176	Phosphorylation	VMESNYETLVSLKVL HHHHCHHHHHEEEEC	23.31	23663014
179	Phosphorylation	SNYETLVSLKVLGQT HCHHHHHEEEECCCC	26.11	23663014
307	Ubiquitination	QECGQGLKLKKDTSR CCCCCCCCCCCCCCC	66.15	-
328	Ubiquitination	CEITFRYKQQLATHL CEEEEEEHHHHHHHH	27.58	-
407	Phosphorylation	QHVQERFSPNSLVAL HHHHHHCCCCCEEEC	29.41	21857030
410	Phosphorylation	QERFSPNSLVALPGH HHHCCCCCEEECCCC	27.83	28348404
435	Phosphorylation	ICGYCGKSFSHPSDL ECCCCCCCCCCHHHH	19.77	-
462	Ubiquitination	YSCTECEKSFVQKQH CCCCHHHHHHHHHHH	61.93	-
467	Ubiquitination	CEKSFVQKQHLLQHQ HHHHHHHHHHHHHHH	34.09	-
475	Ubiquitination	QHLLQHQKIHQRERG HHHHHHHHHHHHHCC	39.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN212_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN212_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN212_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZZZ3_HUMAN	ZZZ3	physical	20211142
PRGC2_HUMAN	PPARGC1B	physical	20211142
ATF3_HUMAN	ATF3	physical	18255255
CR3L2_HUMAN	CREB3L2	physical	18255255
CSK_HUMAN	CSK	physical	18255255
REQU_HUMAN	DPF2	physical	18255255
DUS6_HUMAN	DUSP6	physical	18255255
FHL2_HUMAN	FHL2	physical	18255255
GNL1_HUMAN	GNL1	physical	18255255
HBP1_HUMAN	HBP1	physical	18255255
S30BP_HUMAN	SAP30BP	physical	18255255
IKBA_HUMAN	NFKBIA	physical	18255255
NKX23_HUMAN	NKX2-3	physical	18255255
TP4A1_HUMAN	PTP4A1	physical	18255255
RND1_HUMAN	RND1	physical	18255255
ZN212_HUMAN	ZNF212	physical	18255255
ZNF3_HUMAN	ZNF3	physical	18255255
ZN331_HUMAN	ZNF331	physical	18255255
ZN408_HUMAN	ZNF408	physical	18255255
SUV92_HUMAN	SUV39H2	physical	23455924
SF3A3_HUMAN	SF3A3	physical	25416956
F90A1_HUMAN	FAM90A1	physical	25416956
AEDO_HUMAN	ADO	physical	28514442
ZN398_HUMAN	ZNF398	physical	28514442
ZN282_HUMAN	ZNF282	physical	28514442
ZN746_HUMAN	ZNF746	physical	28514442
EPDR1_HUMAN	EPDR1	physical	28514442
ZN777_HUMAN	ZNF777	physical	28514442
RRP44_HUMAN	DIS3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.