NKX23_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NKX23_HUMAN
• UniProt AC: Q8TAU0
• Protein Name: Homeobox protein Nkx-2.3
• Gene Name: NKX2-3
• Organism: Homo sapiens (Human).
• Sequence Length: 364
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor..
• Protein Sequence: MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAACAQGTLQGIRAW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MMLPSPVTSTPF ---CCCCCCCCCCCC	28.21	29759185
8	Phosphorylation	MMLPSPVTSTPFSVK CCCCCCCCCCCCCHH	30.21	24043423
9	Phosphorylation	MLPSPVTSTPFSVKD CCCCCCCCCCCCHHH	34.03	24043423
10	Phosphorylation	LPSPVTSTPFSVKDI CCCCCCCCCCCHHHH	20.98	24043423
13	Phosphorylation	PVTSTPFSVKDILNL CCCCCCCCHHHHCCH	29.48	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NKX23_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NKX23_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NKX23_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NKX23_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.