ZN398_HUMAN - dbPTM
ZN398_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN398_HUMAN
UniProt AC Q8TD17
Protein Name Zinc finger protein 398
Gene Name ZNF398
Organism Homo sapiens (Human).
Sequence Length 642
Subcellular Localization Nucleus .
Protein Description Function as a transcriptional activator..
Protein Sequence MAEAAPAPTSEWDSECLTSLQPLPLPTPPAANEAHLQTAAISLWTVVAAVQAIERKVEIHSRRLLHLEGRTGTAEKKLASCEKTVTELGNQLEGKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWILRLPPGIKGDIPKVPVAFDDVSIYFSTPEWEKLEEWQKELYKNIMKGNYESLISMDYAINQPDVLSQIQPEGEHNTEDQAGPEESEIPTDPSEEPGISTSDILSWIKQEEEPQVGAPPESKESDVYKSTYADEELVIKAEGLARSSLCPEVPVPFSSPPAAAKDAFSDVAFKSQQSTSMTPFGRPATDLPEASEGQVTFTQLGSYPLPPPVGEQVFSCHHCGKNLSQDMLLTHQCSHATEHPLPCAQCPKHFTPQADLSSTSQDHASETPPTCPHCARTFTHPSRLTYHLRVHNSTERPFPCPDCPKRFADQARLTSHRRAHASERPFRCAQCGRSFSLKISLLLHQRGHAQERPFSCPQCGIDFNGHSALIRHQMIHTGERPYPCTDCSKSFMRKEHLLNHRRLHTGERPFSCPHCGKSFIRKHHLMKHQRIHTGERPYPCSYCGRSFRYKQTLKDHLRSGHNGGCGGDSDPSGQPPNPPGPLITGLETSGLGVNTEGLETNQWYGEGSGGGVL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
80PhosphorylationTAEKKLASCEKTVTE
CHHHHHHHCCHHHHH		32.9929396449
83UbiquitinationKKLASCEKTVTELGN
HHHHHCCHHHHHHHH		53.26-
84PhosphorylationKLASCEKTVTELGNQ
HHHHCCHHHHHHHHH		15.4629396449
86PhosphorylationASCEKTVTELGNQLE
HHCCHHHHHHHHHHH		30.6229396449
101PhosphorylationGKWAVLGTLLQEYGL
HHHHHHHHHHHHHHH		21.82-
106PhosphorylationLGTLLQEYGLLQRRL
HHHHHHHHHHHHHHH		10.5017053785
165UbiquitinationEKLEEWQKELYKNIM
HHHHHHHHHHHHHHH		51.24-
265SumoylationADEELVIKAEGLARS
CCHHHHHEEEHHCCC		32.6728112733
265SumoylationADEELVIKAEGLARS
CCHHHHHEEEHHCCC		32.67-
283PhosphorylationPEVPVPFSSPPAAAK
CCCCCCCCCCCHHHH		35.5525159151
284PhosphorylationEVPVPFSSPPAAAKD
CCCCCCCCCCHHHHH		34.9725627689
422PhosphorylationYHLRVHNSTERPFPC
EEEEECCCCCCCCCC		19.4328555341
463PhosphorylationRCAQCGRSFSLKISL
CHHHCCCCEEHHHHH		12.4124719451
465PhosphorylationAQCGRSFSLKISLLL
HHCCCCEEHHHHHHH		29.9624719451
469PhosphorylationRSFSLKISLLLHQRG
CCEEHHHHHHHHHCC		16.0427251275
506PhosphorylationIRHQMIHTGERPYPC
HHEEEECCCCCCCCC		29.7929214152
562PhosphorylationMKHQRIHTGERPYPC
HHCCCCCCCCCCCCC		38.0628555341
567PhosphorylationIHTGERPYPCSYCGR
CCCCCCCCCCCCCCC		24.08-
571PhosphorylationERPYPCSYCGRSFRY
CCCCCCCCCCCCEEE		12.97-
578PhosphorylationYCGRSFRYKQTLKDH
CCCCCEEEHHHHHHH		12.87-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN398_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN398_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN398_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ESR1_HUMANESR1physical
11779858
PKHF2_HUMANPLEKHF2physical
25416956
CIB3_HUMANCIB3physical
25416956
ZN282_HUMANZNF282physical
28514442
ZN746_HUMANZNF746physical
28514442
ZN783_HUMANZNF783physical
28514442
LRP4_HUMANLRP4physical
28514442
ZN777_HUMANZNF777physical
28514442
H2A2B_HUMANHIST2H2ABphysical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN398_HUMAN

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Related Literatures of Post-Translational Modification

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