ZN777_HUMAN - dbPTM
ZN777_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN777_HUMAN
UniProt AC Q9ULD5
Protein Name Zinc finger protein 777
Gene Name ZNF777
Organism Homo sapiens (Human).
Sequence Length 760
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MENQRSSPLSFPSVPQEETLRQAPAGLPRETLFQSRVLPPKEIPSLSPTIPRQGSLPQTSSAPKQETSGRMPHVLQKGPSLLCSAASEQETSLQGPLASQEGTQYPPPAAAEQEVSLLSHSPHHQEAPVHSPEAPEKDPLTLSPTVPETDMDPLLQSPVSQKDTPFQISSAVQKEQPLPTAEITRLAVWAAVQAVERKLEAQAMRLLTLEGRTGTNEKKIADCEKTAVEFANHLESKWVVLGTLLQEYGLLQRRLENMENLLKNRNFWILRLPPGSNGEVPKVPVTFDDVAVHFSEQEWGNLSEWQKELYKNVMRGNYESLVSMDYAISKPDLMSQMERGERPTMQEQEDSEEGETPTDPSAAHDGIVIKIEVQTNDEGSESLETPEPLMGQVEEHGFQDSELGDPCGEQPDLDMQEPENTLEESTEGSSEFSELKQMLVQQRNCTEGIVIKTEEQDEEEEEEEEDELPQHLQSLGQLSGRYEASMYQTPLPGEMSPEGEESPPPLQLGNPAVKRLAPSVHGERHLSENRGASSQQQRNRRGERPFTCMECGKSFRLKINLIIHQRNHIKEGPYECAECEISFRHKQQLTLHQRIHRVRGGCVSPERGPTFNPKHALKPRPKSPSSGSGGGGPKPYKCPECDSSFSHKSSLTKHQITHTGERPYTCPECKKSFRLHISLVIHQRVHAGKHEVSFICSLCGKSFSRPSHLLRHQRTHTGERPFKCPECEKSFSEKSKLTNHCRVHSRERPPPRWSSSFCSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
6Phosphorylation--MENQRSSPLSFPS
--CCCCCCCCCCCCC		26.9230266825
7Phosphorylation-MENQRSSPLSFPSV
-CCCCCCCCCCCCCC		31.8630266825
10PhosphorylationNQRSSPLSFPSVPQE
CCCCCCCCCCCCCHH		38.2030266825
13PhosphorylationSSPLSFPSVPQEETL
CCCCCCCCCCHHHHH		44.4030266825
19PhosphorylationPSVPQEETLRQAPAG
CCCCHHHHHHHCCCC		26.8723186163
31PhosphorylationPAGLPRETLFQSRVL
CCCCCHHHHCCCCCC		33.8727251275
35PhosphorylationPRETLFQSRVLPPKE
CHHHHCCCCCCCCHH		19.6127251275
45PhosphorylationLPPKEIPSLSPTIPR
CCCHHCCCCCCCCCC		47.3323403867
47PhosphorylationPKEIPSLSPTIPRQG
CHHCCCCCCCCCCCC		25.0829255136
49PhosphorylationEIPSLSPTIPRQGSL
HCCCCCCCCCCCCCC		39.9929255136
55PhosphorylationPTIPRQGSLPQTSSA
CCCCCCCCCCCCCCC		28.6527251275
61PhosphorylationGSLPQTSSAPKQETS
CCCCCCCCCCCCCCC		52.5622210691
67PhosphorylationSSAPKQETSGRMPHV
CCCCCCCCCCCCCCH		33.7122210691
121PhosphorylationEVSLLSHSPHHQEAP
HHHHHHCCCCCCCCC		23.6627362937
131PhosphorylationHQEAPVHSPEAPEKD
CCCCCCCCCCCCCCC		25.3527362937
141PhosphorylationAPEKDPLTLSPTVPE
CCCCCCCCCCCCCCC		30.4928102081
143PhosphorylationEKDPLTLSPTVPETD
CCCCCCCCCCCCCCC		17.1828102081
145PhosphorylationDPLTLSPTVPETDMD
CCCCCCCCCCCCCCC		45.3728102081
149PhosphorylationLSPTVPETDMDPLLQ
CCCCCCCCCCCHHHC		30.4728102081
157PhosphorylationDMDPLLQSPVSQKDT
CCCHHHCCCCCCCCC		27.5226074081
160PhosphorylationPLLQSPVSQKDTPFQ
HHHCCCCCCCCCCCC		34.5926074081
169PhosphorylationKDTPFQISSAVQKEQ
CCCCCCCCHHHHCCC		11.0628555341
170PhosphorylationDTPFQISSAVQKEQP
CCCCCCCHHHHCCCC		33.8028555341
174 (in isoform 3)Ubiquitination-52.2821906983
174UbiquitinationQISSAVQKEQPLPTA
CCCHHHHCCCCCCCH		52.2822817900
174 (in isoform 1)Ubiquitination-52.2821906983
174 (in isoform 2)Ubiquitination-52.2821906983
218UbiquitinationGRTGTNEKKIADCEK
CCCCCCHHHHCHHHH		52.1022817900
248PhosphorylationLGTLLQEYGLLQRRL
HHHHHHHHHHHHHHH		10.50-
263UbiquitinationENMENLLKNRNFWIL
HHHHHHHHCCCEEEE		57.96-
263 (in isoform 3)Ubiquitination-57.96-
323PhosphorylationGNYESLVSMDYAISK
CCHHHHHCCEEECCC		15.9522210691
329PhosphorylationVSMDYAISKPDLMSQ
HCCEEECCCHHHHHH		29.9322210691
330SumoylationSMDYAISKPDLMSQM
CCEEECCCHHHHHHH		36.1228112733
330UbiquitinationSMDYAISKPDLMSQM
CCEEECCCHHHHHHH		36.1229967540
344PhosphorylationMERGERPTMQEQEDS
HHCCCCCCCCCHHCC		37.3929978859
351PhosphorylationTMQEQEDSEEGETPT
CCCCHHCCCCCCCCC		36.4727362937
356PhosphorylationEDSEEGETPTDPSAA
HCCCCCCCCCCCCHH		42.2030108239
358PhosphorylationSEEGETPTDPSAAHD
CCCCCCCCCCCHHCC		68.8830576142
361PhosphorylationGETPTDPSAAHDGIV
CCCCCCCCHHCCCEE		40.6829978859
452SumoylationCTEGIVIKTEEQDEE
CCCCEEEECCCCCHH		38.7028112733
496PhosphorylationTPLPGEMSPEGEESP
CCCCCCCCCCCCCCC		18.5925921289
502PhosphorylationMSPEGEESPPPLQLG
CCCCCCCCCCCCCCC		38.1025921289
519PhosphorylationAVKRLAPSVHGERHL
HHHHHCCCCCCHHHH		22.5728555341
554PhosphorylationTCMECGKSFRLKINL
CHHCCCCEEEEEEEE		10.8218187866
604PhosphorylationRVRGGCVSPERGPTF
HHCCCCCCCCCCCCC		25.7223401153
610PhosphorylationVSPERGPTFNPKHAL
CCCCCCCCCCHHHCC		38.5826552605
623PhosphorylationALKPRPKSPSSGSGG
CCCCCCCCCCCCCCC		32.4723401153
625PhosphorylationKPRPKSPSSGSGGGG
CCCCCCCCCCCCCCC		55.1925849741
626PhosphorylationPRPKSPSSGSGGGGP
CCCCCCCCCCCCCCC		40.1223927012
628PhosphorylationPKSPSSGSGGGGPKP
CCCCCCCCCCCCCCC		35.8923927012
636PhosphorylationGGGGPKPYKCPECDS
CCCCCCCCCCCCCCC		31.2027732954
704PhosphorylationSLCGKSFSRPSHLLR
HHCCCCCCCHHHHHH		50.8217081983
715PhosphorylationHLLRHQRTHTGERPF
HHHHCCCCCCCCCCC		19.7428555341
717PhosphorylationLRHQRTHTGERPFKC
HHCCCCCCCCCCCCC		39.8725159151
790 (in isoform 2)Ubiquitination--
790Ubiquitination-------------------------------------
-------------------------------------		-
791 (in isoform 3)Ubiquitination--
801 (in isoform 2)Phosphorylation--
801Phosphorylation------------------------------------------------
------------------------------------------------		-
802 (in isoform 3)Phosphorylation--
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN777_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN777_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN777_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN777_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN777_HUMAN

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-496 AND SER-502, ANDMASS SPECTROMETRY.
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-554, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory