ZN165_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN165_HUMAN
• UniProt AC: P49910
• Protein Name: Zinc finger protein 165
• Gene Name: ZNF165
• Organism: Homo sapiens (Human).
• Sequence Length: 485
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MATEPKKAAAQNSPEDEGLLIVKIEEEEFIHGQDTCLQRSELLKQELCRQLFRQFCYQDSPGPREALSRLRELCCQWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPESGEEAVTILEDLERGTDEAVLQVQAHEHGQEIFQKKVSPPGPALNVKLQPVETKAHFDSSEPQLLWDCDNESENSRSMPKLEIFEKIESQRIISGRISGYISEASGESQDICKSAGRVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNSNEFTHQKSCKHGTCDQSFKWNSDFINHQIIYAGEKNHQYGKSFKSPKLAKHAAVFSGDKTHQCNECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGRAFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEKPYECSECGRAFSQSSNLSQHQRIHMRENLLM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	KKAAAQNSPEDEGLL HHHHHCCCCCCCCEE	20.00	21815630
23	Sumoylation	DEGLLIVKIEEEEFI CCCEEEEEECHHHCC	37.09	28112733
35	Phosphorylation	EFIHGQDTCLQRSEL HCCCCCCCHHHHHHH	13.76	27251275
40	Phosphorylation	QDTCLQRSELLKQEL CCCHHHHHHHHHHHH	21.45	27251275
68	Phosphorylation	PGPREALSRLRELCC CCHHHHHHHHHHHHH	36.00	-
153	Phosphorylation	EIFQKKVSPPGPALN HHHHCCCCCCCCCCE	33.97	25849741
162	Sumoylation	PGPALNVKLQPVETK CCCCCEEEEEECEEE	40.09	28112733
195	Sumoylation	ENSRSMPKLEIFEKI CCCCCCCHHHHHHHH	50.54	28112733
209	Phosphorylation	IESQRIISGRISGYI HHHCCEEECCHHHEE	21.46	22210691
241	Phosphorylation	KRQWEKESGESQRLS HHHHHHHCCCCCCHH	59.95	-
244	Phosphorylation	WEKESGESQRLSSAQ HHHHCCCCCCHHCHH	24.91	-
248	Phosphorylation	SGESQRLSSAQDEGF CCCCCCHHCHHCCCC	26.30	-
324	Ubiquitination	EKNHQYGKSFKSPKL CCCCCCCCCCCCHHH	48.03	-
327	Ubiquitination	HQYGKSFKSPKLAKH CCCCCCCCCHHHHHH	73.30	-
328	Phosphorylation	QYGKSFKSPKLAKHA CCCCCCCCHHHHHHE	25.84	24719451
330	Ubiquitination	GKSFKSPKLAKHAAV CCCCCCHHHHHHEEE	69.07	-
385	Phosphorylation	GKSFAESSDLTRHRR CCCHHHCCCCCCCCC	28.30	23532336
413	Phosphorylation	GRAFNLNSHLIRHQR CCCCCCCHHHHHCCC	23.88	24719451
451	Phosphorylation	IRHFRIHTGEKPYEC HHCEEEECCCCCEEC	44.67	28111955
456	Phosphorylation	IHTGEKPYECSECGR EECCCCCEECCHHHC	40.41	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN165_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN165_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN165_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELOA2_HUMAN	TCEB3B	physical	16189514
CC85B_HUMAN	CCDC85B	physical	16189514
KAT7_HUMAN	KAT7	physical	16189514
CC130_HUMAN	CCDC130	physical	16189514
ZN446_HUMAN	ZNF446	physical	16189514
KR412_HUMAN	KRTAP4-12	physical	16189514
F124A_HUMAN	FAM124A	physical	16189514
SCND1_HUMAN	SCAND1	physical	16189514
PDLI7_HUMAN	PDLIM7	physical	16189514
ZN250_HUMAN	ZNF250	physical	16189514
ZNF24_HUMAN	ZNF24	physical	10567577
ZKSC8_HUMAN	ZKSCAN8	physical	10567577
SUV91_HUMAN	SUV39H1	physical	23455924
SAHH2_HUMAN	AHCYL1	physical	25416956
TRIM1_HUMAN	MID2	physical	25416956
ZN446_HUMAN	ZNF446	physical	25416956
GPT2L_HUMAN	GPATCH2L	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
F124A_HUMAN	FAM124A	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.