TLX3_MOUSE - dbPTM
TLX3_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TLX3_MOUSE
UniProt AC O55144
Protein Name T-cell leukemia homeobox protein 3
Gene Name Tlx3
Organism Mus musculus (Mouse).
Sequence Length 291
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
140PhosphorylationRFVKDRFTAAAALTP
HHHHHHHHHHHHCCC
19.1121454597
149PhosphorylationAAALTPFTVTRRIGH
HHHCCCHHEEECCCC
23.3621454597
162PhosphorylationGHPYQNRTPPKRKKP
CCCCCCCCCCCCCCC
52.04-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TLX3_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TLX3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TLX3_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HNF4G_MOUSEHnf4gphysical
20211142
SMCE1_MOUSESmarce1physical
20211142
TBX21_MOUSETbx21physical
20211142
SIR2_MOUSESirt2physical
20211142
MED31_MOUSEMed31physical
20211142
T2EB_MOUSEGtf2e2physical
20211142
HSBP1_MOUSEHsbp1physical
20211142
CNOT8_MOUSECnot8physical
20211142
TBX18_MOUSETbx18physical
20211142
T22D4_MOUSETsc22d4physical
20211142
ABTB1_MOUSEAbtb1physical
20211142
DEK_MOUSEDekphysical
20211142
TLE6_MOUSETle6physical
20211142
ANKR6_MOUSEAnkrd6physical
20211142
FANCJ_MOUSEBrip1physical
20211142

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TLX3_MOUSE

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Related Literatures of Post-Translational Modification

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