HNF4G_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HNF4G_MOUSE
• UniProt AC: Q9WUU6
• Protein Name: Hepatocyte nuclear factor 4-gamma
• Gene Name: Hnf4g
• Organism: Mus musculus (Mouse).
• Sequence Length: 408
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor. Has a lower transcription activation potential than HNF4-alpha (By similarity)..
• Protein Sequence: MNTTDSGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTYEGSNIPSINTLAQAEVRSCQISVPSPSSSTDINIKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCEVEVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAANDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHTDQIATPETPLPSPPQGSGQEPYKITANQASVISHQSLSKQKQL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
94	Phosphorylation	DRISTRRSTYEGSNI HHHHHCHHHCCCCCC	31.86	-
186	Ubiquitination	HLLLGATKRSMMYKD HHHHCCCHHHHHHHH	41.77	-
370	Phosphorylation	VHTDQIATPETPLPS EECCCCCCCCCCCCC	24.24	-
373	Phosphorylation	DQIATPETPLPSPPQ CCCCCCCCCCCCCCC	31.18	-
377	Phosphorylation	TPETPLPSPPQGSGQ CCCCCCCCCCCCCCC	57.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HNF4G_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HNF4G_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HNF4G_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of HNF4G_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.