T22D4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T22D4_MOUSE
• UniProt AC: Q9EQN3
• Protein Name: TSC22 domain family protein 4
• Gene Name: Tsc22d4
• Organism: Mus musculus (Mouse).
• Sequence Length: 387
• Subcellular Localization: Nucleus .
• Protein Description: Transcriptional repressor..
• Protein Sequence: MSGGKKKSSFQITSVTTDYEGPGSPGASDSPVPPALAGPPPRLPNGDPNPDPGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFGRLLEGIRGASGGTGGRSLDSRLELASLGISTPIPQPGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLAGPGKAKVETPPLSASPPQQRPPGPGTGDSAQTLPSLRVEVESGGSAAATPPLSRRRDGAVRLRMELVAPAETGKVPPTDSRPNSPALYFDASLVHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGLPRLGPSAPNGPSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSGGKKKSSFQITSV CCCCCCCCCEEEEEE	45.31	27087446
24	Phosphorylation	TDYEGPGSPGASDSP ECCCCCCCCCCCCCC	24.24	27087446
30	Phosphorylation	GSPGASDSPVPPALA CCCCCCCCCCCHHHC	25.87	25338131
57	Phosphorylation	PDPGGRGTPRNGSPP CCCCCCCCCCCCCCC	20.08	26824392
62	Phosphorylation	RGTPRNGSPPPGAPA CCCCCCCCCCCCCCH	37.47	27087446
116	Phosphorylation	LEGIRGASGGTGGRS HHHHCCCCCCCCCCC	40.35	27600695
119	Phosphorylation	IRGASGGTGGRSLDS HCCCCCCCCCCCHHH	39.73	30635358
123	Phosphorylation	SGGTGGRSLDSRLEL CCCCCCCCHHHHHHH	39.54	30635358
126	Phosphorylation	TGGRSLDSRLELASL CCCCCHHHHHHHHHC	44.02	19854140
132	Phosphorylation	DSRLELASLGISTPI HHHHHHHHCCCCCCC	39.49	26643407
136	Phosphorylation	ELASLGISTPIPQPG HHHHCCCCCCCCCCC	26.74	26643407
137	Phosphorylation	LASLGISTPIPQPGL HHHCCCCCCCCCCCC	24.26	26643407
145	Phosphorylation	PIPQPGLSQGPTSWL CCCCCCCCCCCCCCC	38.72	26239621
149	Phosphorylation	PGLSQGPTSWLRPPP CCCCCCCCCCCCCCC	39.08	26239621
150	Phosphorylation	GLSQGPTSWLRPPPT CCCCCCCCCCCCCCC	27.52	26239621
157	Phosphorylation	SWLRPPPTSPGPQAR CCCCCCCCCCCCCCC	54.01	25266776
158	Phosphorylation	WLRPPPTSPGPQARS CCCCCCCCCCCCCCC	33.36	25266776
165	Phosphorylation	SPGPQARSFTGGLGQ CCCCCCCCCCCCCCC	30.12	25521595
167	Phosphorylation	GPQARSFTGGLGQLA CCCCCCCCCCCCCCC	31.42	25521595
183	Phosphorylation	PGKAKVETPPLSASP CCCCCCCCCCCCCCC	32.94	26824392
187	Phosphorylation	KVETPPLSASPPQQR CCCCCCCCCCCCCCC	32.26	27742792
189	Phosphorylation	ETPPLSASPPQQRPP CCCCCCCCCCCCCCC	33.46	27087446
200	Phosphorylation	QRPPGPGTGDSAQTL CCCCCCCCCCCCCCC	40.73	25619855
203	Phosphorylation	PGPGTGDSAQTLPSL CCCCCCCCCCCCCCC	24.50	25619855
206	Phosphorylation	GTGDSAQTLPSLRVE CCCCCCCCCCCCEEE	40.11	25619855
209	Phosphorylation	DSAQTLPSLRVEVES CCCCCCCCCEEEEEC	31.74	25619855
216	Phosphorylation	SLRVEVESGGSAAAT CCEEEEECCCCCCCC	54.34	25619855
219	Phosphorylation	VEVESGGSAAATPPL EEEECCCCCCCCCCC	20.47	21082442
223	Phosphorylation	SGGSAAATPPLSRRR CCCCCCCCCCCCCCC	22.25	27087446
227	Phosphorylation	AAATPPLSRRRDGAV CCCCCCCCCCCCCCE	29.52	25619855
252	Phosphorylation	ETGKVPPTDSRPNSP HCCCCCCCCCCCCCC	40.30	26160508
254	Phosphorylation	GKVPPTDSRPNSPAL CCCCCCCCCCCCCCE	52.71	27087446
258	Phosphorylation	PTDSRPNSPALYFDA CCCCCCCCCCEEEEH	17.77	27087446
262	Phosphorylation	RPNSPALYFDASLVH CCCCCCEEEEHHHCC	11.08	27087446
266	Phosphorylation	PALYFDASLVHKSPD CCEEEEHHHCCCCCC	32.54	20531401
271	Phosphorylation	DASLVHKSPDPFGAA EHHHCCCCCCHHHHH	21.47	26824392
282	Phosphorylation	FGAAAAQSLSLARSM HHHHHHHHHHHHHHH	18.39	26643407
284	Phosphorylation	AAAAQSLSLARSMLA HHHHHHHHHHHHHHH	25.82	18846507
288	Phosphorylation	QSLSLARSMLAISGH HHHHHHHHHHHHHCC	16.73	25619855
293	Phosphorylation	ARSMLAISGHLDSDD HHHHHHHHCCCCCCC	17.98	23984901
298	Phosphorylation	AISGHLDSDDDSGSG HHHCCCCCCCCCCCC	49.66	25619855
302	Phosphorylation	HLDSDDDSGSGSLVG CCCCCCCCCCCCEEE	41.68	25619855
304	Phosphorylation	DSDDDSGSGSLVGID CCCCCCCCCCEEEEC	29.21	25619855
306	Phosphorylation	DDDSGSGSLVGIDNK CCCCCCCCEEEECHH	22.91	25619855
337	Ubiquitination	REEVEVLKEQIRDLA HHHHHHHHHHHHHHH	53.39	-
362	Phosphorylation	GLLRALASPEQLAQL HHHHHHCCHHHHHCC	29.80	26745281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T22D4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T22D4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T22D4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of T22D4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.