MZT2_MOUSE - dbPTM
MZT2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MZT2_MOUSE
UniProt AC Q9CQ25
Protein Name Mitotic-spindle organizing protein 2
Gene Name Mzt2
Organism Mus musculus (Mouse).
Sequence Length 159
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle .
Protein Description
Protein Sequence MAAAAAAAGGAALAVSTGLETATLQKLALRRKKVLGAEEMELYELAQAAGAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRLASDPQDSVPISLSTSTSETRGRNRGGPILGNVTISAERGSRERPIQRMPRQPSATRLPKVGGSGKSNSRSSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
100PhosphorylationDSVPISLSTSTSETR
CCCCEEEECCCCCCC
17.3325338131
101PhosphorylationSVPISLSTSTSETRG
CCCEEEECCCCCCCC
41.1225338131
102PhosphorylationVPISLSTSTSETRGR
CCEEEECCCCCCCCC
26.9322067460
111MethylationSETRGRNRGGPILGN
CCCCCCCCCCCCCCE
50.5124129315
120PhosphorylationGPILGNVTISAERGS
CCCCCEEEEECCCCC
17.1426060331
122PhosphorylationILGNVTISAERGSRE
CCCEEEEECCCCCCC
18.0826060331
127PhosphorylationTISAERGSRERPIQR
EEECCCCCCCCCCCC
36.8726824392
140PhosphorylationQRMPRQPSATRLPKV
CCCCCCCCCCCCCCC
33.6526824392
142PhosphorylationMPRQPSATRLPKVGG
CCCCCCCCCCCCCCC
36.7625266776
153PhosphorylationKVGGSGKSNSRSSP-
CCCCCCCCCCCCCC-
43.4921454597
155PhosphorylationGGSGKSNSRSSP---
CCCCCCCCCCCC---
40.40-
157PhosphorylationSGKSNSRSSP-----
CCCCCCCCCC-----
46.9421454597
158PhosphorylationGKSNSRSSP------
CCCCCCCCC------
33.2521454597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MZT2_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MZT2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MZT2_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRIC3_HUMANPRICKLE3physical
20360068
GCP5_HUMANTUBGCP5physical
20360068
MZT2B_HUMANMZT2Bphysical
20360068
NEDD1_HUMANNEDD1physical
20360068
GCP4_HUMANTUBGCP4physical
20360068
GCP6_HUMANTUBGCP6physical
20360068
LG3BP_HUMANLGALS3BPphysical
20360068
GCP3_HUMANTUBGCP3physical
20360068
MZT1_HUMANMZT1physical
20360068
MZT2A_HUMANMZT2Aphysical
20360068
TBG1_HUMANTUBG1physical
20360068
TBG2_HUMANTUBG2physical
20360068
GCP2_HUMANTUBGCP2physical
20360068
SP110_HUMANSP110physical
26496610
LG3BP_HUMANLGALS3BPphysical
26496610
TBG1_HUMANTUBG1physical
26496610
GCP3_HUMANTUBGCP3physical
26496610
GCP2_HUMANTUBGCP2physical
26496610
GCP4_HUMANTUBGCP4physical
26496610
NDK7_HUMANNME7physical
26496610
DCAF8_HUMANDCAF8physical
26496610
CHSTC_HUMANCHST12physical
26496610
MZT2B_HUMANMZT2Bphysical
26496610
GCP6_HUMANTUBGCP6physical
26496610
GCP5_HUMANTUBGCP5physical
26496610
NEDD1_HUMANNEDD1physical
26496610
MZT1_HUMANMZT1physical
26496610

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MZT2_MOUSE

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Related Literatures of Post-Translational Modification

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